PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10028949m
Common NameEUTSA_v10028949mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family MIKC_MADS
Protein Properties Length: 223aa    MW: 25487.9 Da    PI: 9.4678
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10028949mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF96.89.2e-31959151
                     S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
           SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                     krien + rqvtfskRrng+lKKA+ELSvLCdaeva+iifs++gklye+ss
  Thhalv10028949m  9 KRIENATSRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSPRGKLYEFSS 59
                     79***********************************************96 PP

2K-box74.72.5e-25831721099
            K-box  10 eeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkle 99 
                       + ++++ + e   L ++ie+L+ ++R+llGe+L+  s++eLqqLe+qL++sl+kiR+kK++ll+e+ie+l++ke++l  enk+L++k+e
  Thhalv10028949m  83 RDGNSQEGKGETYGLARKIEQLEISKRKLLGEGLDASSIEELQQLENQLDRSLTKIRAKKYQLLREEIEKLKEKERNLIAENKMLKEKYE 172
                      56678888999999*************************************************************************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004321.2E-41160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006632.071161IPR002100Transcription factor, MADS-box
PRINTSPR004044.7E-31323IPR002100Transcription factor, MADS-box
CDDcd002656.36E-40372No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
SuperFamilySSF554553.79E-32374IPR002100Transcription factor, MADS-box
PfamPF003195.3E-271057IPR002100Transcription factor, MADS-box
PRINTSPR004044.7E-312338IPR002100Transcription factor, MADS-box
PRINTSPR004044.7E-313859IPR002100Transcription factor, MADS-box
PfamPF014861.6E-2486171IPR002487Transcription factor, K-box
PROSITE profilePS5129715.28587177IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010076Biological Processmaintenance of floral meristem identity
GO:0010082Biological Processregulation of root meristem growth
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:2000012Biological Processregulation of auxin polar transport
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 223 aa     Download sequence    Send to blast
MVRGKTEMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVALIIFSP RGKLYEFSSS  60
SSITKTVERY QKRIQDLGSD HKRDGNSQEG KGETYGLARK IEQLEISKRK LLGEGLDASS  120
IEELQQLENQ LDRSLTKIRA KKYQLLREEI EKLKEKERNL IAENKMLKEK YEMERGGTVA  180
RTSPSSSTSE EVDIYDNEIE EVVTDLFIGP PETRHSKKFP PN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A1e-16160160MEF2C
5f28_B1e-16160160MEF2C
5f28_C1e-16160160MEF2C
5f28_D1e-16160160MEF2C
6byy_A2e-16160160MEF2 CHIMERA
6byy_B2e-16160160MEF2 CHIMERA
6byy_C2e-16160160MEF2 CHIMERA
6byy_D2e-16160160MEF2 CHIMERA
6bz1_A2e-16160160MEF2 CHIMERA
6bz1_B2e-16160160MEF2 CHIMERA
6bz1_C2e-16160160MEF2 CHIMERA
6bz1_D2e-16160160MEF2 CHIMERA
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that regulates root development by controlling meristem size and patterning of the root apical meristem. Regulates auxin transport and gradients in the root meristematic cells via direct regulation of the auxin efflux carrier PIN1 and PIN4 gene expression. Binds specifically to the CArG-box DNA sequences in the promoter regions of PIN1 and PIN4 genes (PubMed:24121311). Involved in the regulation of shoot apical meristem (SAM) cell identities and transitions. Promotes flowering transition and participates in flower meristem maintenance and determinacy. Positively regulates TFL1 and WUS expression. Binds directly to the TFL1 regulatory sequences (PubMed:25636918). {ECO:0000269|PubMed:24121311}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10028949m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. {ECO:0000269|PubMed:24121311}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2304640.0AK230464.1 Arabidopsis thaliana mRNA for MADS-box protein AGL14, complete cds, clone: RAFL26-03-G06.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006396837.11e-160agamous-like MADS-box protein AGL14
RefseqXP_024010047.11e-160agamous-like MADS-box protein AGL14
SwissprotQ388381e-120AGL14_ARATH; Agamous-like MADS-box protein AGL14
TrEMBLV4KK921e-158V4KK92_EUTSA; Uncharacterized protein
STRINGXP_006396837.11e-159(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM7828413
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G11880.11e-116AGAMOUS-like 14
Publications ? help Back to Top
  1. Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W
    GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox.
    Plant Physiol., 2004. 136(1): p. 2621-32
    [PMID:15375207]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]