PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Thhalv10018987m

Common Name

EUTSA_v10018987mg

Organism

Eutrema salsugineum

Taxonomic ID

72664

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema

Family

MYB

Protein Properties

Length: 278aa MW: 31268.2 Da PI: 4.7164

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Thhalv10018987m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	51.2	2.8e-16	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEd lv +++++G g+W++ +++ g+ R++k+c++rw++yl Thhalv10018987m 14 KGEWTAEEDRMLVAYINEYGLGDWRSLPSRAGLQRCGKSCRLRWLNYL 61 799*******************************************97 PP
2	Myb_DNA-binding	54.1	3.6e-17	67	111	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 rg++T++E+e +++ + + G++ W++Ia+ m+ +Rt++++k++w++ Thhalv10018987m 67 RGKFTPQEEEDIIKFHSLVGNR-WAAIAKQMP-NRTDNDIKNHWNSC 111 89******************.*****.*********975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	13.449	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	7.19E-30	11	108	IPR009057	Homeodomain-like
SMART	SM00717	6.4E-14	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	1.3E-14	14	61	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	2.9E-23	15	68	IPR009057	Homeodomain-like
CDD	cd00167	5.19E-11	16	61	No hit	No description
PROSITE profile	PS51294	25.601	62	116	IPR017930	Myb domain
SMART	SM00717	1.6E-15	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	5.3E-16	67	111	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	3.8E-25	69	116	IPR009057	Homeodomain-like
CDD	cd00167	3.65E-10	69	109	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 278 aa Download sequence Send to blast
MGRTTWFDVD GMKKGEWTAE EDRMLVAYIN EYGLGDWRSL PSRAGLQRCG KSCRLRWLNY 60 LRPGIKRGKF TPQEEEDIIK FHSLVGNRWA AIAKQMPNRT DNDIKNHWNS CLKKRLARNG 120 IDPMTHEPIV TVEASSSTTT TSSPTVLTPS SSCSSSSVSS TGSARLLNKL AAGISSRKHG 180 LDMIKTVILS EPRQAVEEKT MMMISKDEEE EEVIGCFMEI DENMISTTSF NELPCDDSTT 240 TTGFVAAFDD YSSVEPYDLY QSDFYYETDE QLDLFLL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	4e-27	14	116	7	108	B-MYB
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Functional Description ? help Back to Top
Source	Description
UniProt	Functions as a repressor of epidermal cell outgrowth and negatively regulate trichome branch formation (PubMed:18805951, PubMed:21070410). Acts as both a positive and negative regulator of cellular outgrowth. Promotes both trichome expansion and branch formation (PubMed:21070410). Coordinately with WIN1/SHN1, participates in the regulation of cuticle biosynthesis and wax accumulation in reproductive organs and trichomes. Functions in cuticle nanoridge formation in petals and stamens, and in morphogenesis of petal conical cells and trichomes (PubMed:23709630). May play a role in the regulation of cuticle formation in vegetative organs (PubMed:24169067). {ECO:0000269\|PubMed:18805951, ECO:0000269\|PubMed:21070410, ECO:0000269\|PubMed:23709630, ECO:0000269\|PubMed:24169067}.
UniProt	Transcription factor involved in tryptophan gene activation and in indole-3-acetic acid (IAA) and indolic glucosinolates (IG) biosynthesis. Acts as a direct transcriptional activator of both Trp synthesis genes and Trp secondary metabolism genes. {ECO:0000269\|PubMed:15579661, ECO:0000269\|PubMed:23580754, ECO:0000269\|PubMed:23943862, ECO:0000269\|PubMed:9576939}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Thhalv10018987m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by herbivory. {ECO:0000269\|PubMed:23943862}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006390428.1	0.0	transcription factor MYB106
Swissprot	O64399	3e-60	MYB34_ARATH; Transcription factor MYB34
Swissprot	Q9LE63	1e-59	MY106_ARATH; Transcription factor MYB106
TrEMBL	V4K9J5	0.0	V4K9J5_EUTSA; Uncharacterized protein
STRING	XP_006390428.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4	28	2646

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G74430.1	1e-130	myb domain protein 95

Link Out ? help Back to Top
Phytozome	Thhalv10018987m
Entrez Gene	18008093

Publications ? help Back to Top
Grubb CD,Abel S Glucosinolate metabolism and its control. Trends Plant Sci., 2006. 11(2): p. 89-100 [PMID:16406306] De Schutter K, et al. Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint. Plant Cell, 2007. 19(1): p. 211-25 [PMID:17209125] Kim K,Jiang K,Teng SL,Feldman LJ,Huang H Using biologically interrelated experiments to identify pathway genes in Arabidopsis. Bioinformatics, 2012. 28(6): p. 815-22 [PMID:22271267] Guo R, et al. Jasmonic acid and glucose synergistically modulate the accumulation of glucosinolates in Arabidopsis thaliana. J. Exp. Bot., 2013. 64(18): p. 5707-19 [PMID:24151308] Benstein RM, et al. Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis. Plant Cell, 2013. 25(12): p. 5011-29 [PMID:24368794] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Frerigmann H,Gigolashvili T MYB34, MYB51, and MYB122 distinctly regulate indolic glucosinolate biosynthesis in Arabidopsis thaliana. Mol Plant, 2014. 7(5): p. 814-28 [PMID:24431192] Frerigmann H,Gigolashvili T Update on the role of R2R3-MYBs in the regulation of glucosinolates upon sulfur deficiency. Front Plant Sci, 2014. 5: p. 626 [PMID:25426131] Frerigmann H,Glawischnig E,Gigolashvili T The role of MYB34, MYB51 and MYB122 in the regulation of camalexin biosynthesis in Arabidopsis thaliana. Front Plant Sci, 2015. 6: p. 654 [PMID:26379682] Frerigmann H, et al. Regulation of Pathogen-Triggered Tryptophan Metabolism in Arabidopsis thaliana by MYB Transcription Factors and Indole Glucosinolate Conversion Products. Mol Plant, 2016. 9(5): p. 682-695 [PMID:26802248] Stahl E, et al. Regulatory and Functional Aspects of Indolic Metabolism in Plant Systemic Acquired Resistance. Mol Plant, 2016. 9(5): p. 662-681 [PMID:26802249] Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors. Plant Physiol. Biochem., 2016. 102: p. 70-9 [PMID:26913794] Miao H, et al. Glucose enhances indolic glucosinolate biosynthesis without reducing primary sulfur assimilation. Sci Rep, 2016. 6: p. 31854 [PMID:27549907]