PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10018139m
Common NameEUTSA_v10018139mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family ARF
Protein Properties Length: 802aa    MW: 89263.8 Da    PI: 6.4338
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10018139mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B3741.8e-23127227198
                      EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS CS
               B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgr 87 
                      f+k+lt sd++++g +++p++ ae+        ++++++  +l+ +d++ ++W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++
  Thhalv10018139m 127 FCKTLTASDTSTHGGFSVPRRAAEKVfppldytQQPPAQ--ELIARDLHDNEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVTGDSVIFI--RN 216
                      99*****************************96555555..8************************************************..45 PP

                      SEE..EEEEE- CS
               B3  88 sefelvvkvfr 98 
                      ++ +l+++++ 
  Thhalv10018139m 217 ERNQLLLGIRH 227
                      77777998876 PP
2Auxin_resp1102.4e-36253336183
       Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                      aahaa+t+s F+v+Y+Pr+s+seFv ++ k+ ka+  +++svGmRf+m fete+ss rr++Gt++g+ dld+vrWpnS+Wrs+k
  Thhalv10018139m 253 AAHAAATNSCFTVFYHPRSSSSEFVLPLPKYIKAVFhTRISVGMRFRMLFETEESSVRRYMGTITGIGDLDSVRWPNSHWRSVK 336
                      79*******************************986599******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019364.58E-48113256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.105.9E-41120242IPR015300DNA-binding pseudobarrel domain
CDDcd100173.14E-21126219No hitNo description
PfamPF023624.1E-21127227IPR003340B3 DNA binding domain
SMARTSM010197.1E-23127229IPR003340B3 DNA binding domain
PROSITE profilePS5086312.224127229IPR003340B3 DNA binding domain
PfamPF065074.8E-32253336IPR010525Auxin response factor
SuperFamilySSF542772.94E-7694769No hitNo description
PROSITE profilePS5174522.745694778IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0009908Biological Processflower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 802 aa     Download sequence    Send to blast
MNLSTSGFGH QSHEGEKKCL NSELWHACAG PLVSLPSSGS RVVYFPQGHS EQVAATTNKE  60
VEGHIPNYPS LPPQLICQLH NVTMHADVET DEVYAQMVLQ PLTQEEQKDT FVPIELGIPS  120
KQPSNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDYTQ QPPAQELIAR DLHDNEWKFR  180
HIFRGQPKRH LLTTGWSVFV SAKRLVTGDS VIFIRNERNQ LLLGIRHASR PQTIVPSSML  240
SSDSMHIGLL AAAAHAAATN SCFTVFYHPR SSSSEFVLPL PKYIKAVFHT RISVGMRFRM  300
LFETEESSVR RYMGTITGIG DLDSVRWPNS HWRSVKVGWD ESTAGERQAR ASLWEIEPLT  360
TFPMYPSLFP LRLKRPWHPG ASSMHDSRGD IASGLTWFRG GAGENGMLPL NYPSASLFPW  420
MQQSLLGTDQ NQQYQAMLAA GLQNIGGGDP LRQQFVQLQE PNHQYLQQSA SLHNSDLLLQ  480
QHHQASSQQQ LPRHLLQAQT QMTENLPQQN LRQEVSNQVT GQPQQPNRVW QHSDLLSPSF  540
MKSDFADLNN KFTSTANPVQ QQNSTLQGSG DGSNLLNFSI TGQSSVHSEQ IPTQVWSLKH  600
SHPETNEFSE PLSLRQAYGG TSPSLEPPNT QNLSLFGVDS DSGLFLPTTV PHFGTLSADA  660
DTSSMPLTDS GFQNSLYGSM QDTTELLHGA GQTKNFVKVY KSGSVGRSLD ISRFSSYHEL  720
REELGKMFDI KGLLEDAFRS GWQLVFVDKE DDVLLLGDDP WESFVNSVWY IKILSPEDVQ  780
KMGEHGEGGS NGSYPQNLTH F*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1541635747388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00033PBMTransfer from AT5G37020Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10018139m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3527600.0AK352760.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-03-M20.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006391521.10.0auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLE4MW630.0E4MW63_EUTHA; Auxin response factor
TrEMBLV4KG440.0V4KG44_EUTSA; Auxin response factor
STRINGXP_006391521.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM13442894
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]