PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10016136m
Common NameEUTSA_v10016136mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family C3H
Protein Properties Length: 1565aa    MW: 173758 Da    PI: 4.5938
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10016136mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH25.42.4e-0815401563225
                       -S---SGGGGTS--TTTTT-SS-S CS
          zf-CCCH    2 ktelCrffartGtCkyGdrCkFaH 25  
                       +++ C+f++++G+C+ G++C++ H
  Thhalv10016136m 1540 GQRVCKFYQENGHCRKGASCNYLH 1563
                       6899******************** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF579031.9E-8400474IPR011011Zinc finger, FYVE/PHD-type
Gene3DG3DSA:3.30.40.108.9E-10421481IPR013083Zinc finger, RING/FYVE/PHD-type
PROSITE profilePS500168.609425491IPR019787Zinc finger, PHD-finger
CDDcd155682.11E-21427472No hitNo description
SMARTSM002491.7E-7427473IPR001965Zinc finger, PHD-type
PROSITE patternPS013590428488IPR019786Zinc finger, PHD-type, conserved site
Gene3DG3DSA:1.10.245.103.5E-24623716IPR003121SWIB/MDM2 domain
SuperFamilySSF475922.62E-21627713IPR003121SWIB/MDM2 domain
PfamPF022015.9E-13650708IPR003121SWIB/MDM2 domain
PROSITE profilePS5136028.926769901IPR004343Plus-3 domain
SuperFamilySSF1590423.14E-33769898IPR004343Plus-3 domain
SMARTSM007191.4E-50769878IPR004343Plus-3 domain
PfamPF031263.0E-23774876IPR004343Plus-3 domain
SuperFamilySSF552776.02E-1911041169IPR003169GYF domain
CDDcd000722.61E-1911161173No hitNo description
PROSITE profilePS5082916.6211161170IPR003169GYF domain
SMARTSM004448.7E-2411171172IPR003169GYF domain
Gene3DG3DSA:3.30.1490.401.2E-1711171170IPR003169GYF domain
PfamPF022133.3E-1411181158IPR003169GYF domain
PROSITE profilePS5010314.94315381564IPR000571Zinc finger, CCCH-type
PfamPF006426.7E-615401563IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.102.2E-515421564IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010964Biological Processregulation of chromatin silencing by small RNA
GO:0032776Biological ProcessDNA methylation on cytosine
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008270Molecular Functionzinc ion binding
GO:0042393Molecular Functionhistone binding
Sequence ? help Back to Top
Protein Sequence    Length: 1565 aa     Download sequence    Send to blast
MDEKPPSHDI SASEVNGVDS LKVEEKREEE NTQAVEIKLG QNLESEKEKL DVMEEETTAQ  60
AASLEDIVSV DQKIPNEKEV ARVAGFPEIP SQDEKPLEEL QMVQGAKDIS DEFAKEDVGL  120
IVDAMGNQVL KETEEEEEKP GVVTVLEIQA KLQEVDDVVN EVSEKNEASV SESSAGKETV  180
MDDVIEDVEN DPEAGNSVDI HVPEATEEVE TDVKCAACIE EEGDGIDGVR DIGQTIDLEE  240
TREVSEELAK ADETKIAEVS KETETMIEEE NEEKNDDMTD LAEDVETHKD SSSTLIEEGR  300
DDHEEMGKKE MIETQEEAVV GKVDGAKVAE MSEETETRME DEDEEKDEDI NDVETHGGSS  360
ATDIEEGSEN NDEVEMTDTQ EKSVMGETGD EEPEEVEEEN KSAKGKRKRV RNTKTVKGTG  420
KKKEEDVCFM CFDGGDLVLC DRRGCPKAYH PSCVDRDEAF FRSKGKWNCG WHLCSKCEKT  480
ATYLCYTCMF SLCKGCAKDA VFFCIRGNKG LCETCMETVK LIEKKEQEKE PAQLDFDDKT  540
SWEYLFKDYW LDLKSQLSLS PEELDQAKSP QKGNESHSGK QGITRETDYV TDGGSNSDSS  600
PKKRKTRSRS KSSSAEKILS PANKSSSGET MEWASKELLD VVAHMRRGDR SFLPHSEVHA  660
LLLDYIKRYN LRDPRRKSQV ICDSRLQNLF GKSHVGHFEM LNLLDTHFLD KEQQQVDDIQ  720
GSIDDTEPDY VDVDENFDHP VKSGKEKKRK TRKKSVRKGC QSNLDDFAAI DMHNINLIYL  780
RRSLVEDLLG DSTTFEEKVA SAFVRLKIPG VQKQDLYRLV QVIGTPKAPE PYKVGKKTTD  840
FELEILNLDK KEVISIDVIS NQDFTEDECM RLKQSIKCGL INRLTVGDIQ EKAIALQEVR  900
VKNLLEAEIL RFSHLRDRAS DMGRRKELRE CIEKLQKLKS PEERQRRLEE IPGIHVDPKM  960
DPDCESEDED EKEEKEKEKN MRPRSSSFNR RGRDPISPRR GGFRSNESWT STSNFSNNRE  1020
LSRSYSGRGS TGRGDYLGSF EENVSENMWT SGREREREMP QSLGSEKPRS VSTPEPAPRS  1080
SRAIVQPELS PRIVPEILTA PPVVVPQPAP MSNESEKMWH YKDPSGKVQG PFSMAQLRKW  1140
NNTGYFPAKL EIWKATESPL DSILLTDALA GLFQKQTLPV DNSYVKSQVT AYSGQPSQTA  1200
PSILDIPRNS QDTWSSSGSL PSPTPNQITT PTAKRQNFES RWSPTKPSAQ SAVESINMSL  1260
AQSGPSQASR TDIPVVVNSA GALQPSTHLI HGTDITNPSS VNHYGSAPTL PSPTPAGGKQ  1320
SWSNISTDKF DSHGCGGSEG PSSSASYVTA TPSILPSQSQ QGYPQSDLWR IRIPSQPNTQ  1380
SQAPTNNGSW GMNNSQNAGQ PQAPPANQNT GWGQGTANPN MGWTGPVQAG MNVNWAAPSI  1440
PPTGQGMPNP GWGGPVQGQP QPQAYSNTGW GQAQVQAPGR ATGSGWMQTG QGMQSGNSNQ  1500
NWGTQNQTAI PSWGSQHNQN RDSAGYGWNK QSSGQNNFKG QRVCKFYQEN GHCRKGASCN  1560
YLHN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4gnd_A5e-19412501288Histone-lysine N-methyltransferase NSD3
4gnd_C5e-19412501288Histone-lysine N-methyltransferase NSD3
4gne_A5e-19412501288Histone-lysine N-methyltransferase NSD3
4gnf_A5e-19412501288Histone-lysine N-methyltransferase NSD3
4gng_A5e-19412501288Histone-lysine N-methyltransferase NSD3
4gng_D5e-19412501288Histone-lysine N-methyltransferase NSD3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtPlays a central role in integrating RNA silencing and chromatin signals in 21 nt siRNA-dependent DNA methylation on cytosine pathway leading to transcriptional gene silencing of specific sequences. Involved in a chromatin-based RNA silencing pathway that encompasses both post-transcriptional gene silencing (PTGS) (e.g. RDR1, RDR6 and AGO2) and transcriptional gene silencing (TGS) (e.g. siRNA-dependent DNA methylation and histone H3) components. Mediates siRNA accumulation at specific chromatin loci. Binds H3K4me0 through its PHD to enforce low levels of H3K4 methylation and gene silencing at a subset of genomic loci. {ECO:0000269|PubMed:22940247}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10016136m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0070470.0AC007047.7 Arabidopsis thaliana chromosome 2 clone F16F14 map mi398, complete sequence.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006409811.10.0zinc finger CCCH domain-containing protein 19 isoform X1
RefseqXP_024003838.10.0zinc finger CCCH domain-containing protein 19 isoform X1
SwissprotQ9SIV50.0C3H19_ARATH; Zinc finger CCCH domain-containing protein 19
TrEMBLV4M4V30.0V4M4V3_EUTSA; Uncharacterized protein
STRINGXP_006409811.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM54221620
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16485.10.0nucleic acid binding;zinc ion binding;DNA binding