PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Thhalv10002578m | ||||||||
Common Name | EUTSA_v10002558mg | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
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Family | bHLH | ||||||||
Protein Properties | Length: 374aa MW: 42162.4 Da PI: 5.1132 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 38.2 | 2.5e-12 | 165 | 216 | 1 | 55 |
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +r++h ++Er+RR+++N+ + Lr+l+P + + ++ + a+i A+e++++L+ Thhalv10002578m 165 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 216 79****************************...9*****************9995 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:4.10.280.10 | 1.2E-13 | 163 | 219 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 4.00E-12 | 163 | 220 | No hit | No description |
SuperFamily | SSF47459 | 2.49E-16 | 164 | 229 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
PROSITE profile | PS50888 | 15.428 | 164 | 215 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 1.1E-9 | 165 | 216 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 3.4E-9 | 170 | 221 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd04873 | 0.00249 | 299 | 363 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0010377 | Biological Process | guard cell fate commitment | ||||
GO:0045597 | Biological Process | positive regulation of cell differentiation | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 374 aa Download sequence Send to blast |
MIDYMFNRNL QQQKQSMPQQ QQLSPSGFGA TPTFDKMSFA DVMQFADFGP KLALNQTRNQ 60 DDQETGMDPV YFLKFPVLND KIEDHNQTHH LMSQEGGECE GNIGNVFLEE KENQDDENDN 120 NSVQLRFIGE QEDEDRENKN VTTKEVKSKR KRARTSKTSE EVESQRMTHI AVERNRRKQM 180 NEHLRVLRSL MPGSYVQRGD QASIIGGAIE FVRELEQLLQ CLESQKRRRI LGETGSRQIG 240 DMNTTTTSSS PITSVANPLI ITGSVTELEG GGGGLREETA EKKSCLADVE VKLLGFDAMI 300 KILSRRRPGQ LIKTIAALED LQLSILHTNI TTMEQTVLYS FNVKITSETK FTAEDIASSI 360 QEIFSFIHAN TTM* |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 165 | 176 | RMTHIAVERNRR |
2 | 225 | 229 | KRRRI |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Thhalv10002578m |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AK221324 | 0.0 | AK221324.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor, complete cds, clone: RAFL25-14-O10. | |||
GenBank | BT028961 | 0.0 | BT028961.1 Arabidopsis thaliana At3g24140 mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006418807.1 | 0.0 | transcription factor FAMA | ||||
Swissprot | Q56YJ8 | 0.0 | FAMA_ARATH; Transcription factor FAMA | ||||
TrEMBL | V4L0U0 | 0.0 | V4L0U0_EUTSA; Uncharacterized protein | ||||
TrEMBL | V4LBV1 | 0.0 | V4LBV1_EUTSA; Uncharacterized protein | ||||
STRING | XP_006418807.1 | 0.0 | (Eutrema salsugineum) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G24140.1 | 1e-173 | bHLH family protein |
Link Out ? help Back to Top | |
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Phytozome | Thhalv10002578m |
Entrez Gene | 18013705 |