PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010938021.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Arecales; Arecaceae; Arecoideae; Cocoseae; Elaeidinae; Elaeis
Family E2F/DP
Protein Properties Length: 253aa    MW: 27564.2 Da    PI: 9.7578
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010938021.1genomeOGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP88.16.5e-28145210171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++ll+++++gi++ln+va++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  XP_010938021.1 145 RYDSSLGLLTKKFINLLKHAQDGILDLNKVAETL---EV--QKRRIYDITNVLEGIGLIEKKIKNRIRWKG 210
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.5E-29143211IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.7E-34145210IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.7E-18145208IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.2E-25147210IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 253 aa     Download sequence    Send to blast
MSGGRPAGNR SVQQRAGQIF PPLKRHPLFP LAKPPFVAPD EYHRFSAADG RRITPDDVSD  60
ALVIKTPLKR KPDQEDNEAA ESSEWTTSPG YAEAVTSPLL TPVSGKGGRT YGRSKGKNSK  120
SGPQTPMSNA CSPSSNSLTP VGTCRYDSSL GLLTKKFINL LKHAQDGILD LNKVAETLEV  180
QKRRIYDITN VLEGIGLIEK KIKNRIRWKG VDGLTPGVLD DDASNLQAEV QNLTLQEHSL  240
DDHIRTGSLK STL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-25140211174PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010938021.10.0transcription factor E2FB
SwissprotQ9FV712e-71E2FB_ARATH; Transcription factor E2FB
TrEMBLF5A6651e-155F5A665_COCNU; E2F protein
STRINGXP_008784098.11e-148(Phoenix dactylifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.35e-74E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]