PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Eucgr.I01881.1.p
Common NameEUGRSUZ_I01881, LOC104419312
Organism
Eucalyptus grandis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus
Family E2F/DP
Protein Properties Length: 402aa    MW: 45439 Da    PI: 8.593
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Eucgr.I01881.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP71.21.2e-223398171
           E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                      rk+ksL++l+++fl+l+++ + +++ l+++a +L    v  +rRRiYD++N+Le+++++++k+kn+++wkg
  Eucgr.I01881.1.p 33 RKDKSLGVLCSNFLRLYNRDDVEVIGLDDAALKL---GV--ERRRIYDVVNILESVGVVARKAKNQYSWKG 98
                      79*****************999************...**..****************************98 PP
2E2F_TDP73.13e-23171251171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                       r+eksL lltq+f+kl+ +s+ ++++l+++a +L+ +      +++k RR+YDi+NV++++nliek     ++k+++rw g
  Eucgr.I01881.1.p 171 RREKSLALLTQNFVKLFLCSNVDMISLDTAAVALLGDnnnttAMRTKIRRLYDIANVFSSMNLIEKtphpdTRKPAFRWLG 251
                       689***************************************9************************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.2E-253199IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467857.71E-153396IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.1E-273398IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.5E-203498IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.104.1E-21168251IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.0E-28171251IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.99E-12173252IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023194.2E-18173251IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 402 aa     Download sequence    Send to blast
MELARVDDPA CHREAAPLGS GELLDSRQHL YCRKDKSLGV LCSNFLRLYN RDDVEVIGLD  60
DAALKLGVER RRIYDVVNIL ESVGVVARKA KNQYSWKGFR AIPNALEKLK EEGLRENSNN  120
SNCGDPAKVF NDAENEGCLD LKFEMQDNSS ASSKSDNKKE RSPGPLSAEN RREKSLALLT  180
QNFVKLFLCS NVDMISLDTA AVALLGDNNN TTAMRTKIRR LYDIANVFSS MNLIEKTPHP  240
DTRKPAFRWL GWRGKSGDTD ANFSEQNQYR KRLFGTEITN QPLKRSKVDS SNNTKSRDPV  300
KKAFLVKQDP ENNYDRCEQE CHSDNGSRGY VYGPFAPVCL PRAVNSAPKS VKQDYDWETL  360
ASTHRPQYHN QALRDLFAHY MEAWKSWYTE VAGNTKIPQV S*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-33332374222Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapEucgr.I01881.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010029245.10.0PREDICTED: E2F transcription factor-like E2FF isoform X1
SwissprotQ8LSZ41e-115E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A059ARS80.0A0A059ARS8_EUCGR; Uncharacterized protein
STRINGXP_010029245.10.0(Eucalyptus grandis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63042743
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-116DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]