PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Eucgr.C03424.1.p

Common Name

EUGRSUZ_C03424

Organism

Eucalyptus grandis

Taxonomic ID

71139

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus

Family

HSF

Protein Properties

Length: 364aa MW: 41406.8 Da PI: 6.033

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Eucgr.C03424.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	111.7	5.2e-35	12	102	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkell 94 Fl+k+ye+++d+ + ++sw + +sfvv+d++ef+k+vLp+yFkhsnf+SF+RQLn+YgF+k++ e+ weF+ + F++gkk+ll Eucgr.C03424.1.p 12 FLRKTYEMVSDPGSDPVVSWGSGRDSFVVWDQHEFSKQVLPRYFKHSNFSSFIRQLNTYGFRKIDMER---------WEFASEGFQAGKKHLL 95 9**************************************************************999.........************ PP XXXXXXX CS HSF_DNA-bind 95 ekikrkk 101 ++ikr+ Eucgr.C03424.1.p 96 KNIKRRG 102 ***95 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	3.2E-54	8	101	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	1.63E-33	8	101	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	3.9E-37	8	101	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	2.4E-17	12	35	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	1.2E-31	12	101	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-17	50	62	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	51	75	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-17	63	75	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 364 aa Download sequence Send to blast
MEGLGEVGPT PFLRKTYEMV SDPGSDPVVS WGSGRDSFVV WDQHEFSKQV LPRYFKHSNF 60 SSFIRQLNTY GFRKIDMERW EFASEGFQAG KKHLLKNIKR RGKFSKHRKT SSSSFTSGYP 120 KAGKEPVLET LKKDQEALKA EILKLREERE NSQHEFDQVA EQVRCAECRH QQMFLFLYKA 180 AKSPNFVQQL IQKRRHKREL DTRESSKKSK LLDPDGATQC LLEAMDPKIQ SPKVDCLTIS 240 DESAQMESQP NSVVLEDFET IQMHNPWPSP LGGRDFRVVQ GQTPDQMAGA SPSHLSSVFH 300 EMSERLLEDN MVVGDNVADV EEVEELVVND SRIYLELEGL IEKPCGWSEY PSGPMEQAAG 360 VMP*

Sequence ? help Back to Top

Protein Sequence Length: 364 aa Download sequence Send to blast

MEGLGEVGPT PFLRKTYEMV SDPGSDPVVS WGSGRDSFVV WDQHEFSKQV LPRYFKHSNF  60
SSFIRQLNTY GFRKIDMERW EFASEGFQAG KKHLLKNIKR RGKFSKHRKT SSSSFTSGYP  120
KAGKEPVLET LKKDQEALKA EILKLREERE NSQHEFDQVA EQVRCAECRH QQMFLFLYKA  180
AKSPNFVQQL IQKRRHKREL DTRESSKKSK LLDPDGATQC LLEAMDPKIQ SPKVDCLTIS  240
DESAQMESQP NSVVLEDFET IQMHNPWPSP LGGRDFRVVQ GQTPDQMAGA SPSHLSSVFH  300
EMSERLLEDN MVVGDNVADV EEVEELVVND SRIYLELEGL IEKPCGWSEY PSGPMEQAAG  360
VMP*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	3e-23	3	101	17	129	Heat shock factor protein 1
5d5v_B	3e-23	3	101	17	129	Heat shock factor protein 1
5d5v_D	3e-23	3	101	17	129	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	94	100	LKNIKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Eucgr.C03424.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat stress, high light and hydrogen peroxide (H(2)O(2)). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010049462.2	0.0	PREDICTED: heat shock factor protein HSF30
Swissprot	O80982	1e-69	HSFA2_ARATH; Heat stress transcription factor A-2
TrEMBL	A0A059CUB3	0.0	A0A059CUB3_EUCGR; Uncharacterized protein
STRING	XP_010049462.1	0.0	(Eucalyptus grandis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7498	19	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G26150.1	5e-72	heat shock transcription factor A2

Link Out ? help Back to Top
Phytozome	Eucgr.C03424.1.p

Publications ? help Back to Top
Liu HC,Charng YY Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development. Plant Physiol., 2013. 163(1): p. 276-90 [PMID:23832625] Jung HS, et al. Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9 [PMID:23918368] Chauhan H,Khurana N,Agarwal P,Khurana JP,Khurana P A seed preferential heat shock transcription factor from wheat provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment. PLoS ONE, 2013. 8(11): p. e79577 [PMID:24265778] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Weng M, et al. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ., 2014. 37(9): p. 2128-38 [PMID:24548003] Jang YH, et al. A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana. Plant J., 2014. 78(4): p. 591-603 [PMID:24580679] Stief A, et al. Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors. Plant Cell, 2014. 26(4): p. 1792-1807 [PMID:24769482] Dobrá J, et al. The impact of heat stress targeting on the hormonal and transcriptomic response in Arabidopsis. Plant Sci., 2015. 231: p. 52-61 [PMID:25575991] Yamauchi Y,Kunishima M,Mizutani M,Sugimoto Y Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression. Sci Rep, 2015. 5: p. 8030 [PMID:25619826] Shi H, et al. Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis. J. Pineal Res., 2015. 58(3): p. 335-42 [PMID:25711624] Mueller SP,Krause DM,Mueller MJ,Fekete A Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation. J. Exp. Bot., 2015. 66(15): p. 4517-26 [PMID:25977236] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Hu Z, et al. Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis. Plant J., 2015. 84(6): p. 1178-91 [PMID:26576681] Lämke J,Brzezinka K,Bäurle I HSFA2 orchestrates transcriptional dynamics after heat stress in Arabidopsis thaliana. Transcription, 2016. 7(4): p. 111-4 [PMID:27383578] Wang X,Huang W,Liu J,Yang Z,Huang B Molecular regulation and physiological functions of a novel FaHsfA2c cloned from tall fescue conferring plant tolerance to heat stress. Plant Biotechnol. J., 2017. 15(2): p. 237-248 [PMID:27500592] Chen ST,He NY,Chen JH,Guo FQ Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis. Plant J., 2017. 89(6): p. 1106-1118 [PMID:27943531] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Wang X,Zhuang L,Shi Y,Huang B Up-Regulation of HSFA2c and HSPs by ABA Contributing to Improved Heat Tolerance in Tall Fescue and Arabidopsis. Int J Mol Sci, 2018. [PMID:28914758] Llamas E,Pulido P,Rodriguez-Concepcion M Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. PLoS Genet., 2017. 13(9): p. e1007022 [PMID:28937985] Li X, et al. Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance. Plant Physiol., 2018. 176(4): p. 3027-3045 [PMID:29444814]