PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

EcC048317.10

Organism

Eucalyptus camaldulensis

Taxonomic ID

34316

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus

Family

E2F/DP

Protein Properties

Length: 476aa MW: 51984.9 Da PI: 4.6158

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EcC048317.10	genome	ECGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.5	8.5e-27	153	218	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg EcC048317.10 153 RYDSSLSLLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKIKNRIRWKG 218 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.0E-28	150	220	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	9.7E-34	153	218	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	4.76E-17	153	216	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	5.0E-24	155	218	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	1.7E-33	232	335	No hit	No description
CDD	cd14660	5.66E-50	232	335	No hit	No description
Pfam	PF16421	3.8E-33	234	333	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 476 aa Download sequence Send to blast
MAGGSGTPNR PAPPQAPAAA TGQIFQPPKR HLAFATTKPP FVPPDDYHRF SSSSPADARR 60 SAGADHEADA IVVRSPLLKR KSGTAENEVA SSMWINSPGH VNVINSPFQT PVSAKGGKAY 120 NRSKGSKANK SGPQTPLSND GSPAALTPAG NCRYDSSLSL LTKKFINLIK HAEDGILDLN 180 KAAETLEVQK RRIYDITNVL EGIGLIEKKI KNRIRWKGLD SSRPEDADVD FSRLQAEVEK 240 LSLEERRLDD QIREMQEKLR GLGEDENNQK WLFVTEEDIK GLPCFQNETL IAIKAPHGTT 300 LEVPDPDEAV DYPQRRYRII LRSTMGPIDV YLVSQFEEKF EEMNGMEPPP SLPLASSSGS 360 NENAVSEAVN VDSNRNESDP DGLAYQISLD ANASQEIVGG MMKIVPSDVD NDADYWLLSD 420 ADVSITDMWK TDTGVEWSEV DMLHPDFGIP DASMPRPQTP PSGTTDVPNP VDSANG

Sequence ? help Back to Top

Protein Sequence Length: 476 aa Download sequence Send to blast

MAGGSGTPNR PAPPQAPAAA TGQIFQPPKR HLAFATTKPP FVPPDDYHRF SSSSPADARR  60
SAGADHEADA IVVRSPLLKR KSGTAENEVA SSMWINSPGH VNVINSPFQT PVSAKGGKAY  120
NRSKGSKANK SGPQTPLSND GSPAALTPAG NCRYDSSLSL LTKKFINLIK HAEDGILDLN  180
KAAETLEVQK RRIYDITNVL EGIGLIEKKI KNRIRWKGLD SSRPEDADVD FSRLQAEVEK  240
LSLEERRLDD QIREMQEKLR GLGEDENNQK WLFVTEEDIK GLPCFQNETL IAIKAPHGTT  300
LEVPDPDEAV DYPQRRYRII LRSTMGPIDV YLVSQFEEKF EEMNGMEPPP SLPLASSSGS  360
NENAVSEAVN VDSNRNESDP DGLAYQISLD ANASQEIVGG MMKIVPSDVD NDADYWLLSD  420
ADVSITDMWK TDTGVEWSEV DMLHPDFGIP DASMPRPQTP PSGTTDVPNP VDSANG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-23	148	219	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010059189.1	0.0	PREDICTED: transcription factor E2FA
Swissprot	Q9FNY0	1e-172	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A059DJA8	0.0	A0A059DJA8_EUCGR; Uncharacterized protein
STRING	XP_010059189.1	0.0	(Eucalyptus grandis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM808	28	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-165	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]