PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Do018050.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Dichantheliinae; Dichanthelium
Family bHLH
Protein Properties Length: 568aa    MW: 61942.9 Da    PI: 4.7411
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Do018050.1genomeDichanView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH42.41.3e-13377424355
                 HHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
         HLH   3 rahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                 ++h + Er+RR+++N+ f  L++l+P+        K++Ka+iL +++ Y+k+Lq
  Do018050.1 377 KNHVMSERKRREKLNEMFLALKSLVPSiH------KVDKASILAETIAYVKELQ 424
                 5899***********************66......******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.4E-4821199IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088815.707374423IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.31E-18377438IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000835.23E-16377428No hitNo description
Gene3DG3DSA:4.10.280.109.9E-18378435IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.4E-11378424IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.7E-17380429IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010026Biological Processtrichome differentiation
GO:0010214Biological Processseed coat development
GO:2000029Biological Processregulation of proanthocyanidin biosynthetic process
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 568 aa     Download sequence    Send to blast
MAVALAASPV QEELLQPERQ LRSQLAAAAR TINWSYAIFW SISSTQPGIL TWTDGFYNGE  60
VKTRKIANSA ELTADQLVMQ RSEQLRELYE ALLSGECDRR AARPVASLSP EDLGDTEWYY  120
VVCMTYAFRP GQGLPGRSFA SNEHVWLCNA HLADSKAFPR ALLAKTIVCI PLISGVLELG  180
TTDPVVEDPD LVSQATASFW ELPFPACSEE PGSSPSANET GKASDIIVFE DLDHNAMETM  240
IAGAQELGEA ESLSNASLEH VTKEINEFYS LCEEIDVQPL EDSWIMDGSF EVPSSPQPAP  300
VAAAANDAAT ASTPVGRSRA TSFTAWTRSE SDSDEAAVPV IEEPQKLLKK VVAGGAWAGN  360
NGGGGTARTS QESGIIKNHV MSERKRREKL NEMFLALKSL VPSIHKVDKA SILAETIAYV  420
KELQRRVQEL ESSREPIISR PSGETTRLTR RHDDEVIKVS AGSKRKGSEL GGDVERQRPW  480
TLSKDGASNV TVTVSDKDVL LEVQCRWEEL LLTRVFDAIK SLHLDVLSVQ ASAPEGFMGL  540
KIQAQFASSA AVVPWMISEA LRKAIGKR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A2e-19111995192Transcription factor MYC3
4rqw_B2e-19111995192Transcription factor MYC3
4rs9_A2e-19111995192Transcription factor MYC3
4yz6_A2e-19111995192Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1382387ERKRRE
2383388RKRREK
Functional Description ? help Back to Top
Source Description
UniProtPutative transcriptional activator. Control tissue-specific synthesis of anthocyanin pigments in various parts of the maize plant.
Cis-element ? help Back to Top
SourceLink
PlantRegMapDo018050.1
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025823475.10.0anthocyanin regulatory R-S protein-like isoform X2
SwissprotP135260.0ARLC_MAIZE; Anthocyanin regulatory Lc protein
TrEMBLA0A1E5VA450.0A0A1E5VA45_9POAL; Anthocyanin regulatory Lc protein
STRINGSi000845m0.0(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP93233109
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G09820.15e-79bHLH family protein
Publications ? help Back to Top
  1. Pattanaik S,Xie CH,Yuan L
    The interaction domains of the plant Myc-like bHLH transcription factors can regulate the transactivation strength.
    Planta, 2008. 227(3): p. 707-15
    [PMID:18075757]
  2. Huang ZA, et al.
    The upregulation of NtAN2 expression at low temperature is required for anthocyanin accumulation in juvenile leaves of Lc-transgenic tobacco (Nicotiana tabacum L.).
    J Genet Genomics, 2012. 39(3): p. 149-56
    [PMID:22464474]
  3. Ludwig SR,Habera LF,Dellaporta SL,Wessler SR
    Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region.
    Proc. Natl. Acad. Sci. U.S.A., 1989. 86(18): p. 7092-6
    [PMID:2674946]
  4. Li P, et al.
    Combined bulked segregant sequencing and traditional linkage analysis for identification of candidate gene for purple leaf sheath in maize.
    PLoS ONE, 2018. 13(1): p. e0190670
    [PMID:29304111]