PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Do002201.1
Organism
Dichanthelium oligosanthes
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Dichantheliinae; Dichanthelium
Family E2F/DP
Protein Properties Length: 438aa    MW: 47366.4 Da    PI: 4.4294
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Do002201.1genomeDichanView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.31.9e-26130195171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL+llt+kfl+ll+ ++ giv+ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  Do002201.1 130 RYDSSLGLLTKKFLNLLKGAPGGIVDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNNIRWKG 195
                 6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.2E-28128196IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.77E-16130193IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.6E-35130195IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.6E-23132195IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146605.72E-38206294No hitNo description
SuperFamilySSF1440744.18E-27207291No hitNo description
PfamPF164215.3E-25211294IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 438 aa     Download sequence    Send to blast
MAAAAGGAAG EARARAMLQR HQPFAPPPGE YHNFGAPAVA GEDMVEAVVL RTPLKRKHNR  60
EGNEAAESND WMMSPGYANA GSSPVPTPPS GKGLKTSAKP KASKGQKPCP QTPLNFGSPV  120
NPSTPVGGCR YDSSLGLLTK KFLNLLKGAP GGIVDLNNAA ETLEVQKRRI YDITNVLEGI  180
GLIEKKLKNN IRWKGIDESR PGEVSDDMSI LQSDIEALTL QEQNLDERIS EMRDGLRELT  240
EDENNQKWLY VTEDDIKSLP CFQNQTLIAI KAPHGTTLEV PDPDEDVHLQ LNMKPNIAVL  300
IDCSQFEEMS GMETPPRPAP TISMDSLENP KTPLAAECSK AAGIEPNSIQ GLTLPPDAPS  360
SSQDIGGMMK IVPSELDTDA DYWLLSDTGV SITDMWKTAP AVEWDGIEKF NAEDFLEVST  420
PKQQDKPADV MDGPSCIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-23122196274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapDo002201.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0343490.0BT034349.1 Zea mays full-length cDNA clone ZM_BFc0009D23 mRNA, complete cds.
GenBankBT0644350.0BT064435.1 Zea mays full-length cDNA clone ZM_BFc0168K16 mRNA, complete cds.
GenBankEU9655380.0EU965538.1 Zea mays clone 286746 transcription factor E2F2 mRNA, complete cds.
GenBankEU9739800.0EU973980.1 Zea mays clone 425487 transcription factor E2F2 mRNA, complete cds.
GenBankJX4699700.0JX469970.1 Zea mays subsp. mays clone UT3233 E2F-DP-type transcription factor mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025804811.10.0transcription factor E2FA-like isoform X1
SwissprotQ9FNY01e-100E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A3L6R6R80.0A0A3L6R6R8_PANMI; Transcription factor E2FA-like isoform X1
STRINGPavir.J28624.1.p0.0(Panicum virgatum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.13e-93E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]