PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KZV37188.1

Organism

Dorcoceras hygrometricum

Taxonomic ID

472368

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras

Family

WRKY

Protein Properties

Length: 520aa MW: 56399.6 Da PI: 8.4813

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KZV37188.1	genome	CNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.3	2.1e-30	281	339	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 Dg++WrKYGqK+ kg+++pr+YY+Ct a gCpv+k+v+r+a+d++++++tYeg+Hnh+ KZV37188.1 281 PDGCQWRKYGQKMAKGNPYPRAYYKCTIAlGCPVRKQVQRCASDQTILVTTYEGTHNHP 339 59********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	6.1E-32	265	339	IPR003657	WRKY domain
SuperFamily	SSF118290	7.32E-27	273	340	IPR003657	WRKY domain
PROSITE profile	PS50811	28.575	275	341	IPR003657	WRKY domain
SMART	SM00774	5.2E-36	280	340	IPR003657	WRKY domain
Pfam	PF03106	6.1E-26	282	339	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 520 aa Download sequence Send to blast
MGKGWGLTVE NPDHPAAFVG GVFGKNLSSD MKAGLIMFPV NSSCKEEQAT PSSDQRLALG 60 ELDFFPEKRS PLVRKLEDSY ADVNTGLQLV TGKTGSDQSS VDDGICRSDT GNHKRAKYEV 120 AQLQVELERM NAENHRLRGM LTQISNSYTG LKMHLAALMQ HQQNSTTPNS LQEHLHDIVD 180 RSSKEKKQEN IGGLSSPGGV NKLVSERYSN STSEEKSESG CPELLPRSKR IGRDASPELD 240 DGAPNKVPKL CFTKHDQSTE VATMRKVRVS VRARSEAPMI PDGCQWRKYG QKMAKGNPYP 300 RAYYKCTIAL GCPVRKQVQR CASDQTILVT TYEGTHNHPL LPPAMAMAST TSAAADMLLS 360 GSMPSSDVLM NPNFLAINMV PCSSNMATIS ASAPFPTVTL DLTQSSNSTQ FERPQAHFPA 420 PLHQNIATPP PIPQILSQVM HNQSKFSGLQ MSKDSQSLQH PQHRPLFEET LSATTAAIRA 480 DPNFTSALAA AISSIIGGAS HPNNSKGNAN TTATHTLHGK

Sequence ? help Back to Top

Protein Sequence Length: 520 aa Download sequence Send to blast

MGKGWGLTVE NPDHPAAFVG GVFGKNLSSD MKAGLIMFPV NSSCKEEQAT PSSDQRLALG  60
ELDFFPEKRS PLVRKLEDSY ADVNTGLQLV TGKTGSDQSS VDDGICRSDT GNHKRAKYEV  120
AQLQVELERM NAENHRLRGM LTQISNSYTG LKMHLAALMQ HQQNSTTPNS LQEHLHDIVD  180
RSSKEKKQEN IGGLSSPGGV NKLVSERYSN STSEEKSESG CPELLPRSKR IGRDASPELD  240
DGAPNKVPKL CFTKHDQSTE VATMRKVRVS VRARSEAPMI PDGCQWRKYG QKMAKGNPYP  300
RAYYKCTIAL GCPVRKQVQR CASDQTILVT TYEGTHNHPL LPPAMAMAST TSAAADMLLS  360
GSMPSSDVLM NPNFLAINMV PCSSNMATIS ASAPFPTVTL DLTQSSNSTQ FERPQAHFPA  420
PLHQNIATPP PIPQILSQVM HNQSKFSGLQ MSKDSQSLQH PQHRPLFEET LSATTAAIRA  480
DPNFTSALAA AISSIIGGAS HPNNSKGNAN TTATHTLHGK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	8e-22	271	340	8	76	Probable WRKY transcription factor 4
2lex_A	8e-22	271	340	8	76	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KZV37188.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011096037.1	0.0	WRKY transcription factor 6
Swissprot	Q9C519	1e-122	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A2Z7BU56	0.0	A0A2Z7BU56_9LAMI; Putative WRKY transcription factor 31
STRING	Migut.M01342.1.p	1e-169	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA945	24	92

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-114	WRKY family protein

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]