PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KZV35581.1
Organism
Dorcoceras hygrometricum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras
Family MYB_related
Protein Properties Length: 540aa    MW: 61261.9 Da    PI: 6.4677
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KZV35581.1genomeCNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding408.8e-13106148346
                      SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                       W ++E+ ll+++++++G+ +W+ +a+++g ++t + c++++ +
       KZV35581.1 106 EWNADEEMLLLEGIEMYGMCNWAEVAEHVG-TKTKEACIEHYKN 148
                      6*****************************.***********87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0250242.8E-13535540IPR016827Transcriptional adaptor 2
PROSITE profilePS5013510.8244390IPR000433Zinc finger, ZZ-type
SMARTSM002916.2E-104388IPR000433Zinc finger, ZZ-type
PfamPF005698.2E-104688IPR000433Zinc finger, ZZ-type
CDDcd023351.13E-234795No hitNo description
SuperFamilySSF578502.0E-1347110No hitNo description
PROSITE patternPS0135704976IPR000433Zinc finger, ZZ-type
SuperFamilySSF466892.5E-1299153IPR009057Homeodomain-like
PROSITE profilePS5129321.135102154IPR017884SANT domain
SMARTSM007177.7E-12103152IPR001005SANT/Myb domain
CDDcd001672.21E-12106148No hitNo description
PfamPF002493.8E-12106148IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.9E-8106149IPR009057Homeodomain-like
SuperFamilySSF466892.33E-14446539IPR009057Homeodomain-like
PROSITE profilePS509348.512454540IPR007526SWIRM domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006357Biological Processregulation of transcription from RNA polymerase II promoter
GO:0009631Biological Processcold acclimation
GO:0009733Biological Processresponse to auxin
GO:0009735Biological Processresponse to cytokinin
GO:0016573Biological Processhistone acetylation
GO:0042127Biological Processregulation of cell proliferation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003713Molecular Functiontranscription coactivator activity
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 540 aa     Download sequence    Send to blast
MGRSRGNFHS EEDPSQRSRR KKNASSGENI ESLAAGQVAG EGKRALYHCN YCNKDITGRI  60
RIKCGVCSDF DLCIECFSVG AEVHPHKSGH RYRVMDILSF PLICPEWNAD EEMLLLEGIE  120
MYGMCNWAEV AEHVGTKTKE ACIEHYKNAY LNSPHFPIPD MTHVVGKNRN ELLAMAKGHL  180
DDKKGELQLK EESTFSPSRV KVEESYKSGP SGRLPSTSLA ENFTGAKVKA SNMAHIKDQG  240
DLLKMEDHMS GRSFGGNKPK SAKIEAPSLL DSGGYNAKRQ EFDPEYDNDA EQLLADMEFK  300
ETDTEEEREL KLRVLRIYSK RLDERKRRKD FILDRNILHP SPFLRELSQE EKELCRRYDV  360
FMRFHSKEEH EELIKTVVSE YRIQKRIQEL KEARAAGCRS SAEADRYLEQ KRREAEDGAC  420
LKESYQAGPS SQESLSVPVS SDSFGTYSNT PSAGPANSTH TDMDVVSFSA TNCLSESEKQ  480
LCREIRLAPH DFLKLQAEMT IQFMIGNLSN KSDAYSFFQV DRTKIDGVYD LLLKKGLVQQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6cw2_C9e-38471625120Transcriptional adapter 2
6cw3_E9e-38471625120Transcriptional adapter 2
6cw3_G9e-38471625120Transcriptional adapter 2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1324329RKRRKD
Functional Description ? help Back to Top
Source Description
UniProtRequired for the function of some acidic activation domains, which activate transcription from a distant site. The exact mechanism of action is not yet known (By similarity). ADA2 stimulates the acetyltransferase activity of GCN5 on free histones or nucleosomes, probably by opening up the promoter region. Mediates auxin and cytokinin signals in the control of cell proliferation and might be involved in repression of a freezing tolerance pathway at warm temperature (PubMed:12615937, PubMed:12747832). Involved in the positive regulation of salt-induced gene expression by maintaining locus-specific acetylation of histones H4 and H3 (PubMed:21193996). {ECO:0000250, ECO:0000269|PubMed:12615937, ECO:0000269|PubMed:12747832, ECO:0000269|PubMed:21193996}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKZV35581.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011086259.10.0transcriptional adapter ADA2b isoform X2
SwissprotQ9ATB40.0TAD2B_ARATH; Transcriptional adapter ADA2b
TrEMBLA0A2Z7BM040.0A0A2Z7BM04_9LAMI; Transcriptional adapter
STRINGMigut.H01622.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24471215
Publications ? help Back to Top
  1. Vlachonasios KE,Thomashow MF,Triezenberg SJ
    Disruption mutations of ADA2b and GCN5 transcriptional adaptor genes dramatically affect Arabidopsis growth, development, and gene expression.
    Plant Cell, 2003. 15(3): p. 626-38
    [PMID:12615937]
  2. Sieberer T,Hauser MT,Seifert GJ,Luschnig C
    PROPORZ1, a putative Arabidopsis transcriptional adaptor protein, mediates auxin and cytokinin signals in the control of cell proliferation.
    Curr. Biol., 2003. 13(10): p. 837-42
    [PMID:12747832]
  3. Kerschen A,Napoli CA,Jorgensen RA,Müller AE
    Effectiveness of RNA interference in transgenic plants.
    FEBS Lett., 2004. 566(1-3): p. 223-8
    [PMID:15147899]
  4. Hark AT, et al.
    Two Arabidopsis orthologs of the transcriptional coactivator ADA2 have distinct biological functions.
    Biochim. Biophys. Acta, 2009. 1789(2): p. 117-24
    [PMID:18929690]
  5. Anzola JM, et al.
    Putative Arabidopsis transcriptional adaptor protein (PROPORZ1) is required to modulate histone acetylation in response to auxin.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(22): p. 10308-13
    [PMID:20479223]
  6. Kaldis A,Tsementzi D,Tanriverdi O,Vlachonasios KE
    Arabidopsis thaliana transcriptional co-activators ADA2b and SGF29a are implicated in salt stress responses.
    Planta, 2011. 233(4): p. 749-62
    [PMID:21193996]
  7. Vlachonasios KE,Kaldis A,Nikoloudi A,Tsementzi D
    The role of transcriptional coactivator ADA2b in Arabidopsis abiotic stress responses.
    Plant Signal Behav, 2011. 6(10): p. 1475-8
    [PMID:21897124]
  8. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  9. Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y
    Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology.
    Plant Signal Behav, 2014. 9(3): p. e28211
    [PMID:24614501]
  10. Kim JY,Oh JE,Noh YS,Noh B
    Epigenetic control of juvenile-to-adult phase transition by the Arabidopsis SAGA-like complex.
    Plant J., 2015. 83(3): p. 537-45
    [PMID:26095998]
  11. Kazama D, et al.
    Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis.
    Plants (Basel), 2013. 2(4): p. 769-85
    [PMID:27137403]
  12. Simon MK,Skinner DJ,Gallagher TL,Gasser CS
    Integument Development in Arabidopsis Depends on Interaction of YABBY Protein INNER NO OUTER with Coactivators and Corepressors.
    Genetics, 2017. 207(4): p. 1489-1500
    [PMID:28971961]
  13. Lai J, et al.
    The Transcriptional Coactivator ADA2b Recruits a Structural Maintenance Protein to Double-Strand Breaks during DNA Repair in Plants.
    Plant Physiol., 2018. 176(4): p. 2613-2622
    [PMID:29463775]
  14. Kotak J, et al.
    The histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect leaf development and trichome morphogenesis in Arabidopsis.
    Planta, 2018. 248(3): p. 613-628
    [PMID:29846775]