PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KZV28824.1
Organism
Dorcoceras hygrometricum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras
Family C2H2
Protein Properties Length: 387aa    MW: 44453.7 Da    PI: 6.5701
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KZV28824.1genomeCNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.10.00058145167123
                 EEETTTTEEESSHHHHHHHHHHT CS
     zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                 y C+ C    +rk++L+rH+r++
  KZV28824.1 145 YFCEFCLNFMKRKEQLQRHMRKC 167
                 78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5172675.062111382IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557295.6E-111112383IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.30.60.603.1E-25116168No hitNo description
Gene3DG3DSA:3.40.630.304.6E-73170313IPR016181Acyl-CoA N-acyltransferase
PfamPF018532.2E-84172349IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.0058223281No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016747Molecular Functiontransferase activity, transferring acyl groups other than amino-acyl groups
Sequence ? help Back to Top
Protein Sequence    Length: 387 aa     Download sequence    Send to blast
MVSVTLNAPI SGGASASRNG SAASSEKGPD IEEGGAVRPP HATADYSAAQ PGIDSYRKRK  60
MTMVLHRILD EWVTREHLDL DSVETDVDEK VEDKGHEELD AASLREHEEF TKVKNIATIE  120
LGRYEIETWY FSPFPPEYND CNKLYFCEFC LNFMKRKEQL QRHMRKCDLK HPPGDEIYRD  180
TTLSMFEVDG KKNRVYGQNL CYLAKLFLDH KTLYYDVDLF LFYVLCECDD RGCHMVGYFS  240
KEKHSEESYN LACILTLPPY QRKGYGKFLI AFSYELSKKE NKVGTPERPL SDLGLLSYRG  300
YWTRVLLDIL KKHKGNISIK ELSDMTAIKA EDILSTLQTL ELIQYRKGQH VICADPKVLD  360
RHLKAAGRGG LDVDVCKLIW TPYKEQT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1191073861282Histone acetyltransferase KAT8
4dnc_B1e-1191073861282Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKZV28824.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011074888.10.0histone acetyltransferase of the MYST family 2 isoform X1
RefseqXP_022851241.10.0histone acetyltransferase of the MYST family 1-like isoform X2
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A2Z7BAK00.0A0A2Z7BAK0_9LAMI; Histone acetyltransferase
STRINGMigut.N03322.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA439133
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]