PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Dca57571.1

Organism

Dianthus caryophyllus

Taxonomic ID

3570

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Caryophyllaceae; Caryophylleae; Dianthus

Family

AP2

Protein Properties

Length: 594aa MW: 65063.9 Da PI: 6.9943

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Dca57571.1	genome	DCA	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	42.6	1.5e-13	294	344	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g Dca57571.1 294 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEVEAARAYDKAAIKCNG 344 89******.7**5553..2.26******99********99776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	4.3E-6	222	265	IPR001471	AP2/ERF domain
Pfam	PF00847	4.1E-9	294	344	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.73E-17	294	354	IPR016177	DNA-binding domain
CDD	cd00018	6.78E-25	294	354	No hit	No description
Gene3D	G3DSA:3.30.730.10	2.7E-16	295	352	IPR001471	AP2/ERF domain
SMART	SM00380	1.5E-32	295	358	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	15.672	295	352	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.3E-6	296	307	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.3E-6	334	354	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010073	Biological Process	meristem maintenance
GO:0010093	Biological Process	specification of floral organ identity
GO:0048316	Biological Process	seed development
GO:0048481	Biological Process	plant ovule development
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 594 aa Download sequence Send to blast
MWDLNGTPDE TKRYDDSEGG SSQRTASFDG DDKNSSSSAT AGVVAIEEDD ASPVENKKKR 60 SGFSKIFGFT FSNKNNKNSN DHDDGNNINN VADDEEEEEN NSSSYSGEIP VMHQFFPVEM 120 GLPGTVDTAG PSTTTTTVAY GGGGAGGSVF PRAHWAGVKF CQSTEPTPAV SDVGSVGFGV 180 NSSSSTRHTT TTVNTSIINN KNVEMAQPMK KSRRGPRSRS SQYRGVTYYR RTGRWESHIC 240 AYDRAAIKFR GVDADINFTL EDYQDDLKQM GNLTKEEFVH VLRRQSTGFP RGSSKYRGVT 300 LHKCGRWEAR MGQFLGKKYV YLGLFDTEVE AARAYDKAAI KCNGKDAVTN FDPSIYDEEL 360 KTAECSGSGG GGGGSGGGGG GSGGEHNLDL SLGGSSSNKN GSQLGDNAAV EQQYNNNSMR 420 LEMNWQNRGL RPKEAYRGEN EHGRPREVYG EAETMQLLSQ THLQSPQAML KPNDMHRYAP 480 QFRPPGDGQI PGFIPPHLNS SNYHHFPSSS NGGRVDLMLA SSNNTSQQQQ QQQQLQQQQR 540 QRQQQNQQQQ WQAGDATQRF ATAAASSGFA QQISRPSPHH WMPPNGFHPL MRPS

Sequence ? help Back to Top

Protein Sequence Length: 594 aa Download sequence Send to blast

MWDLNGTPDE TKRYDDSEGG SSQRTASFDG DDKNSSSSAT AGVVAIEEDD ASPVENKKKR  60
SGFSKIFGFT FSNKNNKNSN DHDDGNNINN VADDEEEEEN NSSSYSGEIP VMHQFFPVEM  120
GLPGTVDTAG PSTTTTTVAY GGGGAGGSVF PRAHWAGVKF CQSTEPTPAV SDVGSVGFGV  180
NSSSSTRHTT TTVNTSIINN KNVEMAQPMK KSRRGPRSRS SQYRGVTYYR RTGRWESHIC  240
AYDRAAIKFR GVDADINFTL EDYQDDLKQM GNLTKEEFVH VLRRQSTGFP RGSSKYRGVT  300
LHKCGRWEAR MGQFLGKKYV YLGLFDTEVE AARAYDKAAI KCNGKDAVTN FDPSIYDEEL  360
KTAECSGSGG GGGGSGGGGG GSGGEHNLDL SLGGSSSNKN GSQLGDNAAV EQQYNNNSMR  420
LEMNWQNRGL RPKEAYRGEN EHGRPREVYG EAETMQLLSQ THLQSPQAML KPNDMHRYAP  480
QFRPPGDGQI PGFIPPHLNS SNYHHFPSSS NGGRVDLMLA SSNNTSQQQQ QQQQLQQQQR  540
QRQQQNQQQQ WQAGDATQRF ATAAASSGFA QQISRPSPHH WMPPNGFHPL MRPS

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	367	381	SGGGGGGSGGGGGGS

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269\|PubMed:1675158, ECO:0000269\|PubMed:23034631, ECO:0000269\|PubMed:7919989}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:12893888, ECO:0000269\|PubMed:14555699}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021714342.1	1e-178	floral homeotic protein APETALA 2-like
Swissprot	P47927	1e-100	AP2_ARATH; Floral homeotic protein APETALA 2
TrEMBL	A0A0J8DVY8	1e-174	A0A0J8DVY8_BETVU; Uncharacterized protein
STRING	XP_010667967.1	1e-174	(Beta vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36920.2	1e-78	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Thamilarasan SK,Park JI,Jung HJ,Nou IS Genome-wide analysis of the distribution of AP2/ERF transcription factors reveals duplication and CBFs genes elucidate their potential function in Brassica oleracea. BMC Genomics, 2014. 15: p. 422 [PMID:24888752] Zhang GB,Yi HY,Gong JM The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation. Plant Cell, 2014. 26(10): p. 3984-98 [PMID:25326291] Ranocha P,Francoz E,Burlat V,Dunand C Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion. Plant Signal Behav, 2014. 9(11): p. e977734 [PMID:25531128] Djemal R,Khoudi H Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum). Protoplasma, 2015. 252(6): p. 1461-73 [PMID:25687296] Kazan K Diverse roles of jasmonates and ethylene in abiotic stress tolerance. Trends Plant Sci., 2015. 20(4): p. 219-29 [PMID:25731753] Prunet N, et al. SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signalling. J. Exp. Bot., 2015. 66(21): p. 6905-16 [PMID:26269626] Xie W, et al. Exploring potential new floral organ morphogenesis genes of Arabidopsis thaliana using systems biology approach. Front Plant Sci, 2015. 6: p. 829 [PMID:26528302] Zumajo-Cardona C,Pabón-Mora N Evolution of the APETALA2 Gene Lineage in Seed Plants. Mol. Biol. Evol., 2016. 33(7): p. 1818-32 [PMID:27030733] Zhao Y, et al. An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design. Sci Rep, 2016. 6: p. 23890 [PMID:27033976] Gao R,Liu P,Irwanto N,Loh R,Wong SM Upregulation of LINC-AP2 is negatively correlated with AP2 gene expression with Turnip crinkle virus infection in Arabidopsis thaliana. Plant Cell Rep., 2016. 35(11): p. 2257-2267 [PMID:27473526] Huang Z, et al. APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol., 2017. 215(3): p. 1197-1209 [PMID:27604611] Dory M, et al. Kinase-Associated Phosphoisoform Assay: a novel candidate-based method to detect specific kinase-substrate phosphorylation interactions in vivo. BMC Plant Biol., 2016. 16(1): p. 204 [PMID:27655033] Wang P, et al. Expansion and Functional Divergence of AP2 Group Genes in Spermatophytes Determined by Molecular Evolution and Arabidopsis Mutant Analysis. Front Plant Sci, 2016. 7: p. 1383 [PMID:27703459] Sharma P, et al. Promoter Trapping and Deletion Analysis Show Arabidopsis thaliana APETALA2 Gene Promoter Is Bidirectional and Functions as a Pollen- and Ovule-Specific Promoter in the Reverse Orientation. Appl. Biochem. Biotechnol., 2017. 182(4): p. 1591-1604 [PMID:28130768] Kihira M, et al. Arabidopsis thaliana FLO2 is Involved in Efficiency of Photoassimilate Translocation, Which is Associated with Leaf Growth and Aging, Yield of Seeds and Seed Quality. Plant Cell Physiol., 2017. 58(3): p. 440-450 [PMID:28158741] Balanzà V, et al. Genetic control of meristem arrest and life span in Arabidopsis by a FRUITFULL-APETALA2 pathway. Nat Commun, 2018. 9(1): p. 565 [PMID:29422669] Dotto M,Gómez MS,Soto MS,Casati P UV-B radiation delays flowering time through changes in the PRC2 complex activity and miR156 levels in Arabidopsis thaliana. Plant Cell Environ., 2018. 41(6): p. 1394-1406 [PMID:29447428] Song C,Lee J,Kim T,Hong JC,Lim CO VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis. Planta, 2018. 247(6): p. 1439-1448 [PMID:29536220]