PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

DCAR_031571

Organism

Daucus carota

Taxonomic ID

4039

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus

Family

AP2

Protein Properties

Length: 552aa MW: 60896.5 Da PI: 5.9658

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
DCAR_031571	genome	ARS-USDA	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	34.9	3.7e-11	171	227	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + ++ k + g ++ +e+Aa+a++ a++k++g DCAR_031571 171 SIYRGVTRHRWTGRYEAHLWDnSCR-RegQSrKGRQ-GGYDKEEKAARAYDMAALKYWG 227 57*****************5444.2455536655.779999************98 PP
2	AP2	47.1	6e-15	272	321	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GV+++++ grW A+I + +k +lg+f t+eeAa+a++ a+ k++g DCAR_031571 272 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTEEEAAEAYDIAAIKFRG 321 9*************988532...5**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	1.37E-14	171	236	IPR016177	DNA-binding domain
CDD	cd00018	1.85E-19	171	237	No hit	No description
Pfam	PF00847	2.6E-8	171	227	IPR001471	AP2/ERF domain
SMART	SM00380	1.2E-22	172	241	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.5E-12	172	235	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.451	172	235	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.7E-6	173	184	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.47E-18	270	330	IPR016177	DNA-binding domain
CDD	cd00018	1.26E-24	270	329	No hit	No description
SMART	SM00380	1.6E-32	271	335	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.375	271	329	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.1E-18	271	329	IPR001471	AP2/ERF domain
Pfam	PF00847	1.5E-9	272	321	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.7E-6	311	331	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000723	Biological Process	telomere maintenance
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0007389	Biological Process	pattern specification process
GO:0010073	Biological Process	meristem maintenance
GO:0010449	Biological Process	root meristem growth
GO:0019827	Biological Process	stem cell population maintenance
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 552 aa Download sequence Send to blast
MNSNNWLSFP FSPSNPSLQT HLSSSTDQSQ QFSLGLVSEN DDSPFQHQEW NMMSGQVSSE 60 VPKVADFLGV SKSENQSSDL AVYNNEFHAN ESDYLFTNHN LLQLPNPLAV APPDHSYDIP 120 ENASNLQSLT LSMGSGNKQC ETIGENSEST AIVPVDATPR RTLDTFGQRT SIYRGVTRHR 180 WTGRYEAHLW DNSCRREGQS RKGRQGGYDK EEKAARAYDM AALKYWGTST TTNFPITNYE 240 KELDDMKNMT RQEFVASIRR KSSGFSRGAS MYRGVTRHHQ HGRWQARIGR VAGNKDLYLG 300 TFSTEEEAAE AYDIAAIKFR GLNAVTNFDM NRYDVKSILE SNSLPIGGGA AKRLKEAQAI 360 ESSRKREEMI ALGSAFQYGS SSSGTVLPLQ AYHSLMQQPY HDPNPQPLLT LQNPEISQYS 420 TQEHQFNQSY IQTQLQLHQQ SAVDSYNNSQ LYNSYLQNNP SYLHGFMNMG SSSSVLDNNG 480 SSSNGSYSTG GYLGHSTAGN GSGGVGGSST EELGMVKVDY DMPSGSYNTA GWSGDSSVQG 540 SNPGVFSMWN D*

Sequence ? help Back to Top

Protein Sequence Length: 552 aa Download sequence Send to blast

MNSNNWLSFP FSPSNPSLQT HLSSSTDQSQ QFSLGLVSEN DDSPFQHQEW NMMSGQVSSE  60
VPKVADFLGV SKSENQSSDL AVYNNEFHAN ESDYLFTNHN LLQLPNPLAV APPDHSYDIP  120
ENASNLQSLT LSMGSGNKQC ETIGENSEST AIVPVDATPR RTLDTFGQRT SIYRGVTRHR  180
WTGRYEAHLW DNSCRREGQS RKGRQGGYDK EEKAARAYDM AALKYWGTST TTNFPITNYE  240
KELDDMKNMT RQEFVASIRR KSSGFSRGAS MYRGVTRHHQ HGRWQARIGR VAGNKDLYLG  300
TFSTEEEAAE AYDIAAIKFR GLNAVTNFDM NRYDVKSILE SNSLPIGGGA AKRLKEAQAI  360
ESSRKREEMI ALGSAFQYGS SSSGTVLPLQ AYHSLMQQPY HDPNPQPLLT LQNPEISQYS  420
TQEHQFNQSY IQTQLQLHQQ SAVDSYNNSQ LYNSYLQNNP SYLHGFMNMG SSSSVLDNNG  480
SSSNGSYSTG GYLGHSTAGN GSGGVGGSST EELGMVKVDY DMPSGSYNTA GWSGDSSVQG  540
SNPGVFSMWN D*

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269\|PubMed:15454085, ECO:0000269\|PubMed:15635403, ECO:0000269\|PubMed:16424342, ECO:0000269\|PubMed:20190735}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin accumulation. {ECO:0000269\|PubMed:15454085}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017227623.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor PLT2 isoform X2
Swissprot	Q5YGP7	0.0	PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2
TrEMBL	A0A175YCG3	0.0	A0A175YCG3_DAUCS; Uncharacterized protein
STRING	EOY32584	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2246	24	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G51190.1	0.0	AP2 family protein

Link Out ? help Back to Top
Phytozome	DCAR_031571

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Lee DK,Sieburth LE The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants. Plant Signal Behav, 2012. 7(6): p. 698-700 [PMID:22580686] Hong LW,Yan DW,Liu WC,Chen HG,Lu YT TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis. J. Exp. Bot., 2014. 65(1): p. 275-86 [PMID:24277277] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Zhao Q, et al. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche. J Integr Plant Biol, 2014. 56(12): p. 1151-63 [PMID:24831283] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Yang S, et al. The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance. Plant Cell, 2015. 27(6): p. 1670-80 [PMID:25991732] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Shinohara H,Mori A,Yasue N,Sumida K,Matsubayashi Y Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(14): p. 3897-902 [PMID:27001831] Ou Y, et al. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res., 2016. 26(6): p. 686-98 [PMID:27229312] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis . J Integr Plant Biol, 2017. 59(1): p. 30-43 [PMID:28074634] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]