PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_027886
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family ARF
Protein Properties Length: 878aa    MW: 96687.7 Da    PI: 6.4147
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_027886genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.61.1e-23127228199
                  EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefe 91 
                  f+k+lt sd++++g +++p++ ae+        ++++++  +l+ +d++ ++W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++++ +
  DCAR_027886 127 FCKTLTASDTSTHGGFSVPRRAAEKVfppldftQQPPAQ--ELIARDLHENEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVTGDSVLFI--WNEKNQ 220
                  99*****************************86555544..8************************************************..888999 PP

                  .EEEEE-S CS
           B3  92 lvvkvfrk 99 
                  l+++++r+
  DCAR_027886 221 LFLGIRRA 228
                  9***9986 PP
2Auxin_resp118.74.6e-39253336183
   Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                  aahaa+tks F+++YnPra++seFv++++k++ka++ ++vsvGmRf+m fete+ss rr++Gt++g+sdld+vrW+nS+Wrs+k
  DCAR_027886 253 AAHAATTKSRFTIFYNPRACPSEFVIPLAKYVKAVYhTRVSVGMRFRMLFETEESSVRRYMGTITGISDLDSVRWQNSHWRSVK 336
                  79*********************************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019364.19E-48112256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.7E-40120241IPR015300DNA-binding pseudobarrel domain
CDDcd100172.98E-21126222No hitNo description
PROSITE profilePS5086312.012127229IPR003340B3 DNA binding domain
SMARTSM010196.9E-24127229IPR003340B3 DNA binding domain
PfamPF023625.0E-22127228IPR003340B3 DNA binding domain
PfamPF065077.3E-34253336IPR010525Auxin response factor
PfamPF023091.8E-6739829IPR033389AUX/IAA domain
SuperFamilySSF542772.35E-6741820No hitNo description
PROSITE profilePS5174523.655744828IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 878 aa     Download sequence    Send to blast
MRLSTASFSQ QSPEGEKSCS NSELWHACAG PLVSLPAIGS RVVYFPQGHS EQVVASTNKE  60
VDAHIPNYPS LPPQLICQLH NITMHADAET DEVYAQMTLQ PLSPDEQKEA FLPVDLGAPS  120
KQPTNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDFTQ QPPAQELIAR DLHENEWKFR  180
HIFRGQPKRH LLTTGWSVFV SAKRLVTGDS VLFIWNEKNQ LFLGIRRAIR PQTVMPSSVL  240
SCDSMHLGLL AAAAHAATTK SRFTIFYNPR ACPSEFVIPL AKYVKAVYHT RVSVGMRFRM  300
LFETEESSVR RYMGTITGIS DLDSVRWQNS HWRSVKVGWD ESTAGERQPR VSLWEIEPLT  360
TFPMYPSPFP FRLKRPWPAG LPSFNGNHVS GLHNYNCHLY SVPCAGMKES VLGMNSPHMW  420
LQGDNGDRGF QSLNFQGIGV TPWMQPRVDA SVLGMQTADI YQTMAAAALQ EMRAVDTSKN  480
PIPSVLQFQQ SQSVPHRSSS GLLHTQMLQQ SQPEASFLYC GGETQSQAQS FGPLLSHSAS  540
QAQTPSLQTM NTMQHQSFSD SNGKPVTSSV VSPLNNLAGS YSNDENTQLF NCSRSSGLLT  600
SEGWPPKRVA VDPVSSFGAS HSVLPQIDQL GSLHTNITQH AFSLPPYPGR DCSINQDGDN  660
DPQNCLRFGV NIDSTPLFMQ NGISGLRGVG SDGDSTTIPF TSSNYMSTAG ADFSLNPSVT  720
ASSCIDEPNF LQSPENLGQE STPATFVKVY KSGSFGRSLD IAKFSSYIEL RSELAHMFGL  780
EGDLEDPLRS GWQLVFVDRE NDVLLLGDDP WPEFVNSVWC IKILSLQEMQ QMGKLGLELL  840
NSVPVHRLSS NNCENYPSQQ GSKNLSNGIA SMGAHDY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1581635747388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017235549.10.0PREDICTED: auxin response factor 6-like
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A175YPE10.0A0A175YPE1_DAUCS; Auxin response factor
STRINGcassava4.1_001357m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA23682452
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]