PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_025655
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family ARF
Protein Properties Length: 754aa    MW: 83226.3 Da    PI: 7.5265
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_025655genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B3733.6e-23176277199
                  EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefe 91 
                  f+k+lt sd++++g +++ +++a+e+        +++  +++l+ +d++g++W++++i+r++++r++l++GW+ Fv++++L +gD ++F   + +++ 
  DCAR_025655 176 FCKTLTASDTSTHGGFSVLRRHADEClppldmtRQPP--TQELVAKDLHGNEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGENGD 269
                  99****************************9754333..459************************************************..348888 PP

                  .EEEEE-S CS
           B3  92 lvvkvfrk 99 
                  l+v+v+r+
  DCAR_025655 270 LRVGVRRA 277
                  9****985 PP
2Auxin_resp83.74e-283123761983
   Auxin_resp  19 astseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                  +s+seF+v+++++++++k+++s+GmRfkm+fe+e+++e+r++Gt+vg++++dp +Wp+S Wr Lk
  DCAR_025655 312 TSPSEFIVPYDQYMESVKSNYSIGMRFKMRFEGEEAPEQRFTGTIVGTEEADPKSWPGSMWRFLK 376
                  689***********************************************************996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.101.7E-41169291IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019361.57E-40172305IPR015300DNA-binding pseudobarrel domain
CDDcd100171.91E-21174276No hitNo description
SMARTSM010196.0E-22176278IPR003340B3 DNA binding domain
PROSITE profilePS5086311.73176278IPR003340B3 DNA binding domain
PfamPF023624.1E-21176277IPR003340B3 DNA binding domain
PfamPF065072.9E-25312376IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 754 aa     Download sequence    Send to blast
MTSTEVLSKG ANNPRGASLY NDRNDVGAAP ANSGGGKGKF RLFSGDGDRD LVAYMFVRVF  60
VGVVDADTAL YTELWKACAG PLVTVPRQHE LVYYFPQGHI EQVEASTNQV AEQQMPMYNL  120
PSKILCRVVN VNLKAEPDTD EVFAQVTLMP EPNQDENTAR KDPVPPPQPH FNVHSFCKTL  180
TASDTSTHGG FSVLRRHADE CLPPLDMTRQ PPTQELVAKD LHGNEWRFRH IFRGQPRRHL  240
LQSGWSVFVS SKRLVAGDAF IFLRGENGDL RVGVRRALRQ QTNVPSSVIS SHSMHLGVLA  300
TAWHAIQTGT MTSPSEFIVP YDQYMESVKS NYSIGMRFKM RFEGEEAPEQ RFTGTIVGTE  360
EADPKSWPGS MWRFLKVRWD ETSSIPRPDT VSPWKIEPAL SPPALNPLPV PRQKRPRSNL  420
LPYSPDSSVL TREGSSKVAT DPLPSIGFSR VLQVQEISTL GGNFAESIES DLSDKPVVWP  480
RSTDDEKTDV PTSQRYRSEK WSPLGRGESS FTDLLSGFGS QTNSSHDLVV PSSVQTTATA  540
NSKKLQLHEE EGNFNSVSSR WPMMSSNLSL NLGSGSNGHM QGSDAYQTRR DTRYGNYNNC  600
LVQPGHMGDQ NQGLMPPPHS YYHSMPVHSR EAMPRSSPTG QEANKPKDRN CKLFGIPLVS  660
STVTTETVAA QRNTMIEAAG DMHLGLQPHR SPIFESDKWS EHLKGSKVAI NSIAHDEQEK  720
SLPSCQPTVK DGQSKVPGGS TRSCTKVIAC VNT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1686939818354Auxin response factor 1
4ldw_A1e-1686939818354Auxin response factor 1
4ldw_B1e-1686939818354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor (PubMed:26959229, PubMed:26716451, PubMed:27645097, PubMed:28167023). Involved in the control of fruit ripening process (PubMed:26959229, PubMed:26716451, PubMed:28167023). Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26959229, PubMed:26716451). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). Regulates vegetative growth, lateral root formation and flower organ senescence, possibly partially by regulating gene expression of auxin and ethylene response factor (ERF) genes (PubMed:28167023). Plays a negative role in axillary shoot meristem formation (PubMed:27645097). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression in tomato fruits is up-regulated by exogenous application of ethylene and down-regulated by inhibition of ethylene receptors with 1-methylcyclopropene (1-MCP) (PubMed:26959229, PubMed:26716451). Up-regulated by plant hormone abscisic acid (ABA) in tomato fruits (PubMed:26959229). Expression is not up-regulated by plant hormone auxin in tomato fruits (PubMed:26716451). Up-regulated by auxin and gibberellic acid (GA), and down-regulated by ethylene in seedlings (PubMed:28167023). Down-regulated during decapitation-induced axillary shoot development and by excision of immature leaves. Down-regulation is inhibited by the application of auxin on the cut surface (PubMed:27645097). {ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017218451.10.0PREDICTED: auxin response factor 2-like
SwissprotQ2LAJ30.0ARF2A_SOLLC; Auxin response factor 2A
TrEMBLA0A161ZQ580.0A0A161ZQ58_DAUCS; Auxin response factor
STRINGXP_009769542.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA26182444
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]
  3. Xu T, et al.
    SlARF2a plays a negative role in mediating axillary shoot formation.
    Sci Rep, 2016. 6: p. 33728
    [PMID:27645097]
  4. Ren Z,Liu R,Gu W,Dong X
    The Solanum lycopersicum auxin response factor SlARF2 participates in regulating lateral root formation and flower organ senescence.
    Plant Sci., 2017. 256: p. 103-111
    [PMID:28167023]