PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_024949
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family GRF
Protein Properties Length: 358aa    MW: 39722.2 Da    PI: 8.6643
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_024949genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC75.26.7e-2483127145
          WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 
                  d+epgrCrRtDGKkWRC +++++++k+CErH++rgr+rsrk++e+
  DCAR_024949  83 DPEPGRCRRTDGKKWRCAKDAYPDSKYCERHMNRGRNRSRKPVES 127
                  79****************************************986 PP
2QLQ62.11.5e-212256236
          QLQ  2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiq 36
                 +FTa Q+q+L++Q+l+yKyL+a++ vPpeL+++i+
  DCAR_024949 22 PFTAVQWQELEHQALIYKYLMAGLSVPPELVAPIR 56
                 9********************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009512.0E-122157IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088804.5E-162256IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166623.262257IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166724.44383127IPR014977WRC domain
PfamPF088792.0E-2084126IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 358 aa     Download sequence    Send to blast
MSGLSTAAAA SVTVAVDGFR PPFTAVQWQE LEHQALIYKY LMAGLSVPPE LVAPIRMSLE  60
ALPSRFFHHS ALGYCSYYGK KFDPEPGRCR RTDGKKWRCA KDAYPDSKYC ERHMNRGRNR  120
SRKPVESQST SQSLSTATSQ MLSGVSTTGG SFQGRGSGSS YNQPLYPIAN TENLSYGTSK  180
FQMEPSTYGY NNKEYRYLQG VTPNADEYNF LSEASNSAKG LGMDSNENTW RLMPPQVHSN  240
PLLKPRNDSY LQGDSTQLHL PQANELGAAM SKQQQQYCFF GNNVDSLGTL KQEPNSKRPF  300
FNDDDGCNKN SFSTTQLSIS IPMGSSEYLS PSVCTPDECR FSHFRASRGK EKVLHSN*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:24532604). Transcription activator that plays a regulatory role in grain development (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates grain size by promoting cell division and expansion, leading to increased grain length and width (PubMed:26187814, PubMed:27250747, PubMed:27250749, PubMed:26936408, PubMed:27107174). Positively regulates the expression of genes promoting cell proliferation (PubMed:26187814, PubMed:26936408). Activates the expression of expansin genes to promote cell expansion and grain size (PubMed:27250747). May promote grain size by activating brassinosteroid responses (PubMed:27250747). Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable). Component of the miRNA396c-GRF4-GIF1 regulatory module that plays an important role in grain size determination (Probable) (PubMed:27250747, PubMed:27250749, PubMed:27107174). {ECO:0000269|PubMed:24532604, ECO:0000269|PubMed:26187814, ECO:0000269|PubMed:26936408, ECO:0000269|PubMed:27107174, ECO:0000269|PubMed:27250747, ECO:0000269|PubMed:27250749, ECO:0000305|PubMed:26187814, ECO:0000305|PubMed:27107174, ECO:0000305|PubMed:27250747, ECO:0000305|PubMed:27250749}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: The microRNA396c negatively regulates GRF4 at the transcriptional level. {ECO:0000269|PubMed:26187814, ECO:0000269|PubMed:26936408, ECO:0000269|PubMed:27107174, ECO:0000269|PubMed:27250747}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY3031702e-53AY303170.1 Solanum bulbocastanum chromosome 8 clone UW3A14, complete sequence.
GenBankAY3031712e-53AY303171.1 Solanum bulbocastanum chromosome 8 clone UW177O13, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017219169.10.0PREDICTED: growth-regulating factor 4-like
SwissprotQ6ZIK56e-73GRF4_ORYSJ; Growth-regulating factor 4
TrEMBLA0A164TR160.0A0A164TR16_DAUCS; Uncharacterized protein
STRINGSolyc08g075950.1.11e-150(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA7432384
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G13960.15e-47growth-regulating factor 5
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Kuijt SJ, et al.
    Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.
    Plant Physiol., 2014. 164(4): p. 1952-66
    [PMID:24532604]
  3. Hu J, et al.
    A Rare Allele of GS2 Enhances Grain Size and Grain Yield in Rice.
    Mol Plant, 2015. 8(10): p. 1455-65
    [PMID:26187814]
  4. Sun P, et al.
    OsGRF4 controls grain shape, panicle length and seed shattering in rice.
    J Integr Plant Biol, 2016. 58(10): p. 836-847
    [PMID:26936408]
  5. Li S, et al.
    The OsmiR396c-OsGRF4-OsGIF1 regulatory module determines grain size and yield in rice.
    Plant Biotechnol. J., 2016. 14(11): p. 2134-2146
    [PMID:27107174]
  6. Che R, et al.
    Control of grain size and rice yield by GL2-mediated brassinosteroid responses.
    Nat Plants, 2015. 2: p. 15195
    [PMID:27250747]
  7. Duan P, et al.
    Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice.
    Nat Plants, 2015. 2: p. 15203
    [PMID:27250749]