PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_023260
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family HD-ZIP
Protein Properties Length: 700aa    MW: 77869.9 Da    PI: 6.7749
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_023260genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox611.8e-192477356
                 --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
     Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                 + ++++++q+++Le +F+++++p++++r eL+++lgL+ rq+k+WFqNrR++ k
  DCAR_023260 24 HYQRHNAQQIQRLEGAFNECPHPDEKMRMELSRELGLSPRQIKFWFQNRRTQLK 77
                 678899********************************************9877 PP
2START140.81.3e-442244445206
                  HHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS....SCEEEEEEEECCSCHHH.HHHHHHCCCGGCT-TT-S....EEEEEEEECTT.. CS
        START   5 eaaqelvkkalaeepgWvkss....esengdevlqkfeeskv...dsgealrasgvvdmvla.llveellddkeqWdetla....kaetlevissg.. 88 
                   a++el+k+ + ++p+W +ss    e +n + + ++f++ +     ++e +r+ gvv+m     lv  ++d + +W e ++    +a+t+evis+g  
  DCAR_023260 224 NAMNELIKLLENNSPFWIRSSadgtEVLNLEAYESIFPRVGRspyVRIESSRDLGVVIMSGClGLVDMFMDAN-KWMEIFPnivsRASTVEVISTGlm 320
                  689******************9999999999999999887779999*************97746777788888.************************ PP

                  ....EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCE.EEEEEEE-EE--SSXX.HH CS
        START  89 ....galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksngh.skvtwvehvdlkgrlp.hw 179
                      g +qlm+ elq+lsplvp R+++f+R+++q  + +w+ivdvS d +q+   s s  Ra++lpSg+ i+++ +g+  ++tw+ehv+ ++  p h+
  DCAR_023260 321 gsrnGQIQLMYEELQVLSPLVPtREYYFLRFCQQIDQTTWAIVDVSYDFPQELH-SNSQYRARRLPSGCFIQDMLDGRlKQITWMEHVEIEDIRPiHS 417
                  ****************************************************99.9**********************999***********9999** PP

                  HHHHHHHHHHHHHHHHHHHHTXXXXXX CS
        START 180 llrslvksglaegaktwvatlqrqcek 206
                  l+r  + sgla+g+ +++++lqr ce+
  DCAR_023260 418 LFREYICSGLAFGVTRKLSALQRACER 444
                  *************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.1E-21481IPR009057Homeodomain-like
SuperFamilySSF466891.71E-191079IPR009057Homeodomain-like
PROSITE profilePS5007117.0061979IPR001356Homeobox domain
SMARTSM003897.5E-192183IPR001356Homeobox domain
CDDcd000864.22E-182280No hitNo description
PfamPF000464.7E-172477IPR001356Homeobox domain
PROSITE patternPS0002705477IPR017970Homeobox, conserved site
PROSITE profilePS5084842.025211447IPR002913START domain
SuperFamilySSF559616.46E-28212445No hitNo description
CDDcd088751.37E-99215443No hitNo description
SMARTSM002341.3E-34220444IPR002913START domain
PfamPF018521.0E-36224444IPR002913START domain
Gene3DG3DSA:3.30.530.204.9E-5291408IPR023393START-like domain
SuperFamilySSF559611.1E-15467662No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 700 aa     Download sequence    Send to blast
MADNGDNGGG SGGEGSQSRR RKSHYQRHNA QQIQRLEGAF NECPHPDEKM RMELSRELGL  60
SPRQIKFWFQ NRRTQLKAQH EKADNFVLRS ENDKIRCENI AITEALKNAV CPACVRPDQS  120
DEDVYLKEKK LREENAMLRE ELKRVKTIAA QYMGRPISPL HLGQPLHLSP MDLSRASSGH  180
NGMTGLSLDP DLLSGSSSTF KTLPFQQIFI SDMDKSLMID VCRNAMNELI KLLENNSPFW  240
IRSSADGTEV LNLEAYESIF PRVGRSPYVR IESSRDLGVV IMSGCLGLVD MFMDANKWME  300
IFPNIVSRAS TVEVISTGLM GSRNGQIQLM YEELQVLSPL VPTREYYFLR FCQQIDQTTW  360
AIVDVSYDFP QELHSNSQYR ARRLPSGCFI QDMLDGRLKQ ITWMEHVEIE DIRPIHSLFR  420
EYICSGLAFG VTRKLSALQR ACERLTCLID AANSFSHLGG VITSHHGKKS LMQLSQRIVN  480
SFCSSINSVN GQQVMLSGMN DFEVRATLQK CTDPGHPNSM VLSAATSIWL PFSPQKVFDF  540
LRDERSRPQW DVLSNHNPVQ EVGHIACGSH PGNCISVLRA FNTSQNNMLI LQESCIDSSG  600
ALVVYCPVDL PAITIAMSSE DSSFIPVLSS GFAILPDAGK KLGAGEMAVG SIVTVVVQII  660
VSNLTSGKLS QESVNTVNNL VGNTIQHIKA ALNCSPCLD*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
11722SRRRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017257147.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A164UUG60.0A0A164UUG6_DAUCS; Uncharacterized protein
STRINGXP_004299483.10.0(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]