PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID DCAR_014006
Organism
Daucus carota
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus
Family HD-ZIP
Protein Properties Length: 714aa    MW: 79169 Da    PI: 6.7585
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
DCAR_014006genomeARS-USDAView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.98.3e-192580156
                 TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
     Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                 +++ +++t++q++ Le  F++ ++p++++r +L+++lgL+ rq+k+WFqNrR+++k
  DCAR_014006 25 KKRYHRHTANQIQKLEGIFKEFPHPDEKMRMQLSRELGLSPRQIKFWFQNRRTQMK 80
                 678899***********************************************998 PP
2START171.26.8e-542234472206
                  HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEE CS
        START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetlevi 85 
                  +a  a++el+++ + +ep+W+ks+    e +n + + ++f++ ++        +ea+r+sgvv+m+   lv+ +ld++ +W e l+    +a+t++vi
  DCAR_014006 223 IARNAMEELIRLLQGNEPFWMKSAtdgkEVLNLESYERIFPRVNShlknpnVYVEASRDSGVVIMNGLALVNLFLDSN-KWVELLPtivsRAATIAVI 319
                  56789*******************99988899999999999988899999999*************************.*****999999******** PP

                  CTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSX CS
        START  86 ssg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrl 176
                  s+g      g lqlm++elq+lsplvp R f+++R+++q ++g+w+ivdvS d +q+     s  Ra++ pSg+li++++ng+skvtw+eh++++++ 
  DCAR_014006 320 SPGtigsqsGSLQLMYQELQVLSPLVPtRQFYSLRFCQQIEEGSWAIVDVSYDLPQDSL-FTSQCRARRMPSGCLIQDMPNGYSKVTWMEHMEVEDKG 416
                  *********************************************************87.79999********************************* PP

                  X.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
        START 177 p.hwllrslvksglaegaktwvatlqrqcek 206
                  p h l++  + sgla+ga +w +tlqr+ce+
  DCAR_014006 417 PvHRLYKDHIYSGLAFGAERWISTLQRSCER 447
                  *****************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466892.17E-19882IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.603.6E-211076IPR009057Homeodomain-like
PROSITE profilePS5007117.4752282IPR001356Homeobox domain
SMARTSM003891.9E-182386IPR001356Homeobox domain
CDDcd000862.50E-182483No hitNo description
PfamPF000462.4E-162580IPR001356Homeobox domain
PROSITE patternPS0002705780IPR017970Homeobox, conserved site
SuperFamilySSF559613.19E-34213448No hitNo description
PROSITE profilePS5084848.225213450IPR002913START domain
CDDcd088757.59E-110217446No hitNo description
SMARTSM002342.8E-45222447IPR002913START domain
PfamPF018526.8E-46223447IPR002913START domain
Gene3DG3DSA:3.30.530.201.8E-4325413IPR023393START-like domain
SuperFamilySSF559611.51E-19468650No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 714 aa     Download sequence    Send to blast
MEFGSGAGGG SGDDNHDVLD PHRRKKRYHR HTANQIQKLE GIFKEFPHPD EKMRMQLSRE  60
LGLSPRQIKF WFQNRRTQMK AQHERADNCA LRAENDKIRC ENIAIREALK NVICPSCGGP  120
PIGEDPYFDE QKLHMENLHL KEELDRVSSV AAKYIGRPIS QLPPIQPIHI SSLDLSMGSY  180
GIQGMSGPSL DLDLLPGSSL NVPNIPYQST SITDMDKTLM TDIARNAMEE LIRLLQGNEP  240
FWMKSATDGK EVLNLESYER IFPRVNSHLK NPNVYVEASR DSGVVIMNGL ALVNLFLDSN  300
KWVELLPTIV SRAATIAVIS PGTIGSQSGS LQLMYQELQV LSPLVPTRQF YSLRFCQQIE  360
EGSWAIVDVS YDLPQDSLFT SQCRARRMPS GCLIQDMPNG YSKVTWMEHM EVEDKGPVHR  420
LYKDHIYSGL AFGAERWIST LQRSCERVAC SMVTGTTTRD VGGVITSPYG KRSMMKLAQR  480
MVNNFCSIIN LPNSQQWTAL SGTPNEFEVR ANLHRFANLG QPHGMVLSAA ATIWLPLPPQ  540
IVFNFFRDER TRPQWDVLSD HNPVQEVAHI ANGSHSGNCI SVLRAFNTSQ SNMLVLQESC  600
IDSSGSLVVY SPVDLPAINI AMSGEDTSYI PLLPSGFTIS PDGRTSTLQT VHEGASSSSS  660
TTTTGSLLTI VIQIMVSHMA STTTKMSQES VNTVNNLIGN TVQQIKVALN SST*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017245021.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A162AB210.0A0A162AB21_DAUCS; Uncharacterized protein
STRINGXP_008375041.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]