PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.386080.11
Common NameCsa_6G141360, LOC101215773
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HD-ZIP
Protein Properties Length: 842aa    MW: 91875.6 Da    PI: 6.1811
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.386080.11genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.71.9e-182583357
                     --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
         Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                     k  ++t+eq+e+Le++++++++ps  +r++L + +    +++ +q+kvWFqNrR +ek+
  Cucsa.386080.11 25 KYVRYTSEQVEALERVYAECPKPSSLRRQQLVRDCpilsNIEPKQIKVWFQNRRCREKQ 83
                     56789****************************************************97 PP
2START156.22.6e-491653732205
                      HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEE CS
            START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galql 93 
                      +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+++ g a+ra+g+v  ++    +e+l+d++ W +++++ e+      g  g+++l
  Cucsa.386080.11 165 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQSCGGVAARACGLVSLEPS-KIAEILKDRPSWFRDCRSLEVFTMFPAGngGTIEL 257
                      7899******************************************************.7777777777***********999999999***** PP

                      EEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHH CS
            START  94 mvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrs 183
                       +++ +a+++l+p Rdf+++Ry+ +l+ g++v++++S++     p+    +++vRae+lpSg+li+p+++g+s +++v+h +l++++++++lr+
  Cucsa.386080.11 258 VYTQVYAPTTLAPaRDFWTLRYTITLENGSLVVCERSLSGSGAGPSeaaAAQFVRAEMLPSGYLIRPCEGGGSIIHIVDHLNLEAWHVPEVLRP 351
                      ***************************************88777777999******************************************** PP

                      HHHHHHHHHHHHHHHHTXXXXX CS
            START 184 lvksglaegaktwvatlqrqce 205
                      l++s+ + ++k++ a+l++ ++
  Cucsa.386080.11 352 LYESSKVVAQKMTIAALRYVRQ 373
                      *****************98765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.4672084IPR001356Homeobox domain
SMARTSM003896.9E-162288IPR001356Homeobox domain
SuperFamilySSF466891.37E-162287IPR009057Homeodomain-like
CDDcd000868.29E-162585No hitNo description
PfamPF000464.1E-162683IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.605.2E-182783IPR009057Homeodomain-like
CDDcd146868.15E-677116No hitNo description
PROSITE profilePS5084826.784155383IPR002913START domain
CDDcd088754.54E-71159375No hitNo description
SuperFamilySSF559613.57E-34164376No hitNo description
SMARTSM002341.0E-40164374IPR002913START domain
Gene3DG3DSA:3.30.530.202.2E-19164366IPR023393START-like domain
PfamPF018525.4E-47165373IPR002913START domain
PfamPF086702.1E-48697840IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 842 aa     Download sequence    Send to blast
MAMAIAHHRE SSTGSITRHL DSSGKYVRYT SEQVEALERV YAECPKPSSL RRQQLVRDCP  60
ILSNIEPKQI KVWFQNRRCR EKQRKEASRL QTVNRKLNAM NKLLMEENDR LQKQVSQLVC  120
ENGFMRQQLH TVPAAATADA SCDSVVTTPQ PSRRDANNPA GLLSIAEETL AEFLSKATGT  180
AVDWVQMPGM KPGPDSVGIF AISQSCGGVA ARACGLVSLE PSKIAEILKD RPSWFRDCRS  240
LEVFTMFPAG NGGTIELVYT QVYAPTTLAP ARDFWTLRYT ITLENGSLVV CERSLSGSGA  300
GPSEAAAAQF VRAEMLPSGY LIRPCEGGGS IIHIVDHLNL EAWHVPEVLR PLYESSKVVA  360
QKMTIAALRY VRQIAQETSG EVVYGLGRQP AVLRTFSQRL SRGFNDAVNG FNDNGWSLIN  420
CEGAEDVVLT VNSTKNFGTT SNPANSLTYP GGVLCAKASM LLQNVPPAVL VRFLREHRSE  480
WADFNIDAYS AATLKANSYT YPGMRPTRFT GSQIIMPLGH TIEHEELLEV IRLEGHPMVQ  540
EDAFVSRDIH LLQICSGIDE NAVGACSELI FAPIDEMFPD DAPLLPSGFR IIPLDSRTSD  600
AKGSQRTLDL TSSLEVGSGT SNTAGDASSS QSARSVLTIA FQFPFESSMQ DNVANMAHQY  660
VRSVISSVQR VAMAISPSGG GPALGPKLSP GSPEALTLAH WICKSYSLQL GTELIKSDSL  720
EGDSLLKNLW NHQDAILCCS LKSLPVFLFA NQAGLDMLET TLVALQDITL DKIFDESGRK  780
ALCADFPKLM QQGFAYLPGG ICASTMGRHV SYEQAVAWKV LEADETTVHC LAFSFINWSF  840
V*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011656997.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA isoform X2
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A0A0KDB20.0A0A0A0KDB2_CUCSA; Uncharacterized protein
STRINGXP_004168121.10.0(Cucumis sativus)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  5. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  6. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  7. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  8. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  9. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]