PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.321980.1
Common NameCsa_3G008920, LOC101207437
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HSF
Protein Properties Length: 519aa    MW: 56999.4 Da    PI: 4.8364
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.321980.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind114.47.5e-36361272102
                     HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXX CS
    HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellek 96 
                     Fl+k+y++++d++++ ++sws ++nsfvv+++ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++         weF+++ F +g+k+ll++
  Cucsa.321980.1  36 FLSKTYDMVDDPATDAVVSWSPTNNSFVVWNPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKHLLKS 121
                     9********************999*****************************************999.........****************** PP

                     XXXXXX CS
    HSF_DNA-bind  97 ikrkks 102
                     i r+k 
  Cucsa.321980.1 122 ITRRKP 127
                     ***985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.5E-4029120IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.5E-6432125IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467853.81E-3632125IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004472.0E-3236125IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.4E-203659IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.4E-207486IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043407599IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.4E-208799IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 519 aa     Download sequence    Send to blast
MDGTANGCDS GLASGSGNSH PTVPAPITNS SAPPPFLSKT YDMVDDPATD AVVSWSPTNN  60
SFVVWNPPEF ARDLLPKYFK HNNFSSFVRQ LNTYGFRKVD PDRWEFANEG FLRGQKHLLK  120
SITRRKPVHG QSQQQPQQSH GQSSSVGACV EVGKFGLEEE VERLKRDKNV LMQELVRLRQ  180
QQQTTDNQLQ TMVQRLQGME QRQQQMMSFL AKAVQSPGFL AQFVQQQNES TRRISEANKK  240
RRLKQDGIAE SDHSPVPDGQ IVKYQPLMNE AAKTMLRQIM KVDTSHLEPS NHNTDNFLIR  300
DGLQSQCAAM DNGNSSSSVS GVTLQEVPPT SSFNSVASGV PHGPSTTKSE IQSSPQATNS  360
DNISASPFAL NAVRGPGARE ASSLSVSETD VIMPELSHLS EMVSENILDV PEVDYRVPEA  420
GNGAFISPNF LDANGTIPID IDNMSPDADI DALLDNSNFW DDLLVQSPCQ DDEVDFLVGG  480
GLPKTNDMQL AENAWDKSKH VDKLTEQMGL LTSEIKRV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B3e-28131252129Heat shock factor protein 1
5d5v_B3e-28131252129Heat shock factor protein 1
5d5v_D3e-28131252129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1237244NKKRRLKQ
2238243KKRRLK
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818600.0LN681860.1 Cucumis melo genomic scaffold, anchoredscaffold00021.
GenBankLN7132600.0LN713260.1 Cucumis melo genomic chromosome, chr_6.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004148748.10.0PREDICTED: heat stress transcription factor A-1d-like
SwissprotQ9LQM71e-172HFA1D_ARATH; Heat stress transcription factor A-1d
TrEMBLA0A0A0L1790.0A0A0A0L179_CUCSA; Uncharacterized protein
STRINGXP_004165050.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18433169
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32330.11e-135heat shock transcription factor A1D
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Higashi Y, et al.
    HsfA1d, a protein identified via FOX hunting using Thellungiella salsuginea cDNAs improves heat tolerance by regulating heat-stress-responsive gene expression.
    Mol Plant, 2013. 6(2): p. 411-22
    [PMID:23393165]
  5. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  6. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  7. Ohama N, et al.
    The Transcriptional Cascade in the Heat Stress Response of Arabidopsis Is Strictly Regulated at the Level of Transcription Factor Expression.
    Plant Cell, 2016. 28(1): p. 181-201
    [PMID:26715648]