PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.311420.1

Common Name

Csa_3G889150, LOC101207893

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

MYB

Protein Properties

Length: 961aa MW: 105807 Da PI: 5.3012

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.311420.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	55.9	9.6e-18	39	85	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEde+l +av + g++Wk+Ia ++ Rt+ qc +rwqk+l Cucsa.311420.1 39 KGQWTPEEDEILRQAVDHFKGKNWKKIAGYFK-DRTDVQCLHRWQKVL 85 799**************************9.**********986 PP
2	Myb_DNA-binding	65.5	9.8e-21	91	137	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+W++eEde+++d+v+++G++ W+tIa +++ gR +kqc++rw+++l Cucsa.311420.1 91 KGPWSKEEDEIIIDLVNKYGPKKWSTIATHLP-GRIGKQCRERWHNHL 137 79****************************.***********97 PP
3	Myb_DNA-binding	48.7	1.7e-15	143	185	1	45
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + +WT+eE++ l++a++ +G++ W+ + ++ gRt++ +k++w+ Cucsa.311420.1 143 KEAWTQEEELALIRAHQIYGNR-WAELTKFLP-GRTDNAIKNHWN 185 579*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	19.964	34	85	IPR017930	Myb domain
SuperFamily	SSF46689	2.51E-15	35	91	IPR009057	Homeodomain-like
SMART	SM00717	1.9E-14	38	87	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-15	39	85	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	8.8E-25	41	97	IPR009057	Homeodomain-like
CDD	cd00167	6.34E-13	42	85	No hit	No description
PROSITE profile	PS51294	33.361	86	141	IPR017930	Myb domain
SuperFamily	SSF46689	2.55E-31	88	184	IPR009057	Homeodomain-like
SMART	SM00717	2.4E-19	90	139	IPR001005	SANT/Myb domain
Pfam	PF00249	9.5E-19	91	137	IPR001005	SANT/Myb domain
CDD	cd00167	5.94E-17	93	137	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.7E-28	98	141	IPR009057	Homeodomain-like
PROSITE profile	PS51294	19.563	142	192	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	2.3E-21	142	192	IPR009057	Homeodomain-like
SMART	SM00717	2.2E-15	142	190	IPR001005	SANT/Myb domain
Pfam	PF00249	1.6E-13	143	186	IPR001005	SANT/Myb domain
CDD	cd00167	4.28E-12	145	185	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 961 aa Download sequence Send to blast
MEGDKTISTP SDNPEEAVRD QRIRALHGRT SGPTRRSTKG QWTPEEDEIL RQAVDHFKGK 60 NWKKIAGYFK DRTDVQCLHR WQKVLNPELV KGPWSKEEDE IIIDLVNKYG PKKWSTIATH 120 LPGRIGKQCR ERWHNHLNPN INKEAWTQEE ELALIRAHQI YGNRWAELTK FLPGRTDNAI 180 KNHWNSSVKK KLDSYFASGL LSQFQDPVPA GQPNKLPVSS SKVLGSGNDS GLKGMDTEEI 240 SECSQDATVS DSLMIDSACA TLNIRKEFQL TEDLGLGKEQ SASPISNSEP YYRPSMEVST 300 CPIAEFAQEM GHSSHSQQNL SNDCRTTSNR EHQCDLNQFP NISSLQVAKE ASQFQSMGHG 360 MGESHGVGDS AQTSSMIKEA VASAQAECMF ISDDECCRVL FSDTKSDRGH LTSNLKGPCV 420 SEMCDYVVPV HSLGTPKVEN NHTLTPQIYN HPSGTDVQEK NSFGQSGMLI PSMVSVNGDV 480 ILLGGTGSNL FVGAVEHGCV TSQQNRFVYK DGTSKPSYFD VADNPEMQEQ PGGSEDLPKA 540 ICEDTFATAA AEADGTGTCT RLDETAKQND KHLDSRALCY EPPRFPSLDV PFFSCDLIQS 600 GSEMQEYSPL GIRQLMMSSL NSVTPFRLWD SPSRDTSPDA VLKSAAKTFT STPSILKKRH 660 RDLMSPLSER RTDKKLETDV TSSLTENFSR LDVVFNDGSD KASILSPSNL KKSIEDSADN 720 KENMYCTFED SNESQDIMIS ENGFPKRCSQ DYTKQGTADT EMISVRSTSE IVPPGVLAEH 780 DANDLLLHSV DQKALNSSTR IKKRHCLSKS EDASNADNVK QIDSTRPQTT ATGIASLPGA 840 GETPFKRSIE SPSAWMSPWF FNSFLPGPRI DTEISIEDIG YFSSPKERSL DAIGLMKQVS 900 ERTAAACANA HEVLGNETPD TLLKGTRMKH LHCDEAVLAE CRVLDFSECG SPGKVGTMGA 960 *

Sequence ? help Back to Top

Protein Sequence Length: 961 aa Download sequence Send to blast

MEGDKTISTP SDNPEEAVRD QRIRALHGRT SGPTRRSTKG QWTPEEDEIL RQAVDHFKGK  60
NWKKIAGYFK DRTDVQCLHR WQKVLNPELV KGPWSKEEDE IIIDLVNKYG PKKWSTIATH  120
LPGRIGKQCR ERWHNHLNPN INKEAWTQEE ELALIRAHQI YGNRWAELTK FLPGRTDNAI  180
KNHWNSSVKK KLDSYFASGL LSQFQDPVPA GQPNKLPVSS SKVLGSGNDS GLKGMDTEEI  240
SECSQDATVS DSLMIDSACA TLNIRKEFQL TEDLGLGKEQ SASPISNSEP YYRPSMEVST  300
CPIAEFAQEM GHSSHSQQNL SNDCRTTSNR EHQCDLNQFP NISSLQVAKE ASQFQSMGHG  360
MGESHGVGDS AQTSSMIKEA VASAQAECMF ISDDECCRVL FSDTKSDRGH LTSNLKGPCV  420
SEMCDYVVPV HSLGTPKVEN NHTLTPQIYN HPSGTDVQEK NSFGQSGMLI PSMVSVNGDV  480
ILLGGTGSNL FVGAVEHGCV TSQQNRFVYK DGTSKPSYFD VADNPEMQEQ PGGSEDLPKA  540
ICEDTFATAA AEADGTGTCT RLDETAKQND KHLDSRALCY EPPRFPSLDV PFFSCDLIQS  600
GSEMQEYSPL GIRQLMMSSL NSVTPFRLWD SPSRDTSPDA VLKSAAKTFT STPSILKKRH  660
RDLMSPLSER RTDKKLETDV TSSLTENFSR LDVVFNDGSD KASILSPSNL KKSIEDSADN  720
KENMYCTFED SNESQDIMIS ENGFPKRCSQ DYTKQGTADT EMISVRSTSE IVPPGVLAEH  780
DANDLLLHSV DQKALNSSTR IKKRHCLSKS EDASNADNVK QIDSTRPQTT ATGIASLPGA  840
GETPFKRSIE SPSAWMSPWF FNSFLPGPRI DTEISIEDIG YFSSPKERSL DAIGLMKQVS  900
ERTAAACANA HEVLGNETPD TLLKGTRMKH LHCDEAVLAE CRVLDFSECG SPGKVGTMGA  960
*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	1e-70	39	192	6	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	1e-70	39	192	6	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Transcription activator involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269\|PubMed:17287251, ECO:0000269\|PubMed:21862669, ECO:0000269\|PubMed:26069325}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Constant levels during cell cycle. Activated by CYCB1. {ECO:0000269\|PubMed:17287251}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681824	0.0	LN681824.1 Cucumis melo genomic scaffold, anchoredscaffold01596.
GenBank	LN713258	0.0	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011652549.1	0.0	PREDICTED: myb-related protein 3R-1
Swissprot	Q9S7G7	0.0	MB3R1_ARATH; Transcription factor MYB3R-1
TrEMBL	A0A0A0LHI7	0.0	A0A0A0LHI7_CUCSA; Uncharacterized protein
STRING	XP_004136432.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF3727	33	62

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G32730.2	0.0	Homeodomain-like protein

Link Out ? help Back to Top
Phytozome	Cucsa.311420.1
Entrez Gene	101207893

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]