PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cucsa.232300.1

Common Name

Csa_2G361490, LOC101217471

Organism

Cucumis sativus

Taxonomic ID

3659

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

C2H2

Protein Properties

Length: 459aa MW: 47180.1 Da PI: 8.7635

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.232300.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.4	1.3e-05	62	84	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Cucsa.232300.1 62 FVCEICNKGFQRDQNLQLHRRGH 84 89*******************88 PP
2	zf-C2H2	15.9	3.7e-05	138	160	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC+ C+k + +s+ k H++t+ Cucsa.232300.1 138 WKCERCSKKYAVQSDWKAHMKTC 160 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.5E-5	61	84	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	8.92E-7	61	84	No hit	No description
PROSITE profile	PS50157	10.949	62	84	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	62	84	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	7.2E-5	62	84	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE pattern	PS00028	0	64	84	IPR007087	Zinc finger, C2H2
SMART	SM00355	96	103	133	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	8.92E-7	133	159	No hit	No description
SMART	SM00355	77	138	158	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 459 aa Download sequence Send to blast
MVSAENNSPT ATVAASSPSA VEIETIDTVT PAKKKRNLPG MPDPTAEVIA LSPKSLLATN 60 RFVCEICNKG FQRDQNLQLH RRGHNLPWKL RQRTSNEIRK RVYVCPEPSC VHHNPARALG 120 DLTGIKKHFS RKHCEKKWKC ERCSKKYAVQ SDWKAHMKTC GTREYKCDCG TLFSRRDSFI 180 THRAFCDALA FASSDSNVIA AAAAVTAAVA SSPLATMPVS PGLSIQSSEP PDIPMGPPPL 240 TPAATSLTSA VASTVNKTCQ TNGGGASVFA GVFSSSPPTV TSAPPNPPHQ LTTGVNRPDG 300 GNDPSTTAIE PTSLSLSTSL FLSCRASASS GSTSASSIFQ DHTPHYSLSP QPAAMSATAL 360 LQKAAQMGVT SSTASSLLRA SGLSLSQSPG PAISMTAGLG LGFGNEPTTR DLLGLGMGGG 420 GGGGGGVSGS GISALFSSFD GCDVEAASPY GGGGSNGL*

Sequence ? help Back to Top

Protein Sequence Length: 459 aa Download sequence Send to blast

MVSAENNSPT ATVAASSPSA VEIETIDTVT PAKKKRNLPG MPDPTAEVIA LSPKSLLATN  60
RFVCEICNKG FQRDQNLQLH RRGHNLPWKL RQRTSNEIRK RVYVCPEPSC VHHNPARALG  120
DLTGIKKHFS RKHCEKKWKC ERCSKKYAVQ SDWKAHMKTC GTREYKCDCG TLFSRRDSFI  180
THRAFCDALA FASSDSNVIA AAAAVTAAVA SSPLATMPVS PGLSIQSSEP PDIPMGPPPL  240
TPAATSLTSA VASTVNKTCQ TNGGGASVFA GVFSSSPPTV TSAPPNPPHQ LTTGVNRPDG  300
GNDPSTTAIE PTSLSLSTSL FLSCRASASS GSTSASSIFQ DHTPHYSLSP QPAAMSATAL  360
LQKAAQMGVT SSTASSLLRA SGLSLSQSPG PAISMTAGLG LGFGNEPTTR DLLGLGMGGG  420
GGGGGGVSGS GISALFSSFD GCDVEAASPY GGGGSNGL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	7e-32	135	189	4	58	Zinc finger protein JACKDAW
5b3h_F	7e-32	135	189	4	58	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681823	0.0	LN681823.1 Cucumis melo genomic scaffold, anchoredscaffold00014.
GenBank	LN713257	0.0	LN713257.1 Cucumis melo genomic chromosome, chr_3.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004152782.1	0.0	PREDICTED: protein indeterminate-domain 2
Swissprot	Q9SCQ6	1e-119	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A0A0LLE5	0.0	A0A0A0LLE5_CUCSA; Uncharacterized protein
STRING	XP_004152782.1	0.0	(Cucumis sativus)
STRING	XP_004160056.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2218	32	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-105	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	Cucsa.232300.1
Entrez Gene	101217471

Publications ? help Back to Top
Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]