PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.104200.1
Common NameCsa_6G499720, LOC101205742
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HD-ZIP
Protein Properties Length: 325aa    MW: 36886.6 Da    PI: 4.6051
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.104200.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.65.2e-1957110356
                     --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                     k+++++ +q+++Le+ Fe ++++  e++ +LA++lgL+ rqV vWFqNrRa++k
  Cucsa.104200.1  57 KKRRLSVDQVKALEKTFEIENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWK 110
                     456899***********************************************9 PP
2HD-ZIP_I/II126.98.8e-4156148193
     HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 
                     ekkrrls +qvk+LE++Fe e+kLeperKv+la+eLglqprqvavWFqnrRAR+ktkqlE+dy  Lk++y++lk++ ++L++++++L +e+ke
  Cucsa.104200.1  56 EKKRRLSVDQVKALEKTFEIENKLEPERKVKLAQELGLQPRQVAVWFQNRRARWKTKQLERDYGLLKANYESLKRSFDTLQQDNDALLKEIKE 148
                     69*************************************************************************************999987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.3E-1940114IPR009057Homeodomain-like
SMARTSM003895.4E-1955116IPR001356Homeobox domain
PROSITE profilePS5007116.98956112IPR001356Homeobox domain
PfamPF000463.3E-1657110IPR001356Homeobox domain
CDDcd000862.13E-1757113No hitNo description
Gene3DG3DSA:1.10.10.603.1E-2059119IPR009057Homeodomain-like
PRINTSPR000319.3E-68392IPR000047Helix-turn-helix motif
PROSITE patternPS00027087110IPR017970Homeobox, conserved site
PRINTSPR000319.3E-692108IPR000047Helix-turn-helix motif
PfamPF021833.5E-16112153IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 325 aa     Download sequence    Send to blast
MKRHGSSDSL GALMSVCPTS EEQSPRNSHV YGREFQSMLD GLDEEGSIEE HCHVGEKKRR  60
LSVDQVKALE KTFEIENKLE PERKVKLAQE LGLQPRQVAV WFQNRRARWK TKQLERDYGL  120
LKANYESLKR SFDTLQQDND ALLKEIKELK SKLEEEKTES NLSVKEEIFV SESDNLLIEQ  180
TTNHLPVDHI SLPVASDHSD DFNYESFRTV GADDGDDQRV EVSLFTDFKD GSSDSDSSAI  240
LNEDNSPNAV VSSATAGMLQ SHHQILSSPA TSLNCYPFQK AAYNNAQQFV KIEEHNFFSG  300
EETCNLFSDE QAPSMHWYCP DQWN*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1104112RRARWKTKQ
2125130ESLKRS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'-CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00271DAPTransfer from AT2G22430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. Self expression regulation. {ECO:0000269|PubMed:10527431, ECO:0000269|PubMed:12065416, ECO:0000269|PubMed:16055682}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818750.0LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007.
GenBankLN7132620.0LN713262.1 Cucumis melo genomic chromosome, chr_8.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004143453.10.0PREDICTED: homeobox-leucine zipper protein ATHB-6
SwissprotP466682e-80ATHB6_ARATH; Homeobox-leucine zipper protein ATHB-6
TrEMBLA0A0A0KGQ30.0A0A0A0KGQ3_CUCSA; Uncharacterized protein
STRINGXP_004143453.10.0(Cucumis sativus)
STRINGXP_004173863.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF18683489
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22430.12e-74homeobox protein 6
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Song L, et al.
    A transcription factor hierarchy defines an environmental stress response network.
    Science, 2017.
    [PMID:27811239]