PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cucsa.098190.2 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 382aa MW: 42682.7 Da PI: 9.0688 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 73.1 | 3e-23 | 23 | 88 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+++ + l+++a++L v +rRRiYDi+NVLe+++++++k+kn+++w+g Cucsa.098190.2 23 RKQKSLGLLCSNFLSLYNHDGVHSIGLDDAASRL---GV--ERRRIYDIVNVLESVGVLSRKAKNQYSWNG 88 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 77.3 | 1.5e-24 | 155 | 235 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ + +++k+RR+YDi+NVL+++nliek ++k+++rw g Cucsa.098190.2 155 RREKSLALLTQNFVKLFICSHVNMISLDEAAKLLLGDghnssIMRTKVRRLYDIANVLSSMNLIEKthttdTRKPAFRWLG 235 689**************************************999**************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 5.4E-26 | 19 | 89 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 5.14E-16 | 22 | 86 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.4E-28 | 23 | 88 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 5.1E-20 | 24 | 88 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 1.6E-23 | 152 | 236 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 9.7E-32 | 155 | 235 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.3E-19 | 157 | 235 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.98E-13 | 157 | 236 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 382 aa Download sequence Send to blast |
MAALPSSSAL PDSSSSRHHT YSRKQKSLGL LCSNFLSLYN HDGVHSIGLD DAASRLGVER 60 RRIYDIVNVL ESVGVLSRKA KNQYSWNGFG AIPKALQDLK EEGLRENCSA SDGNDYAKVS 120 DDEDEDERFS NPTGSQTSTA AVPKSSSSSL KADNRREKSL ALLTQNFVKL FICSHVNMIS 180 LDEAAKLLLG DGHNSSIMRT KVRRLYDIAN VLSSMNLIEK THTTDTRKPA FRWLGVRGKV 240 KNEPTLLPES RKRAFGTDVT NVSYKKTKAE NSAYQGFNHC LNMQKLVQCD NSSQEDSQNS 300 QDQECERTSK SYQFGPFAPV SVAKVGVLDN NNVKRTHDWE NLSSTFRPQY HNQALKELFS 360 HYVEAWKSWY SEAVKKPIQI S* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 4e-42 | 22 | 227 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | LN681932 | 0.0 | LN681932.1 Cucumis melo genomic scaffold, anchoredscaffold00001. | |||
GenBank | LN713266 | 0.0 | LN713266.1 Cucumis melo genomic chromosome, chr_12. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011651402.1 | 0.0 | PREDICTED: E2F transcription factor-like E2FE isoform X2 | ||||
Swissprot | Q8LSZ4 | 1e-130 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A1S3AW13 | 0.0 | A0A1S3AW13_CUCME; E2F transcription factor-like E2FE isoform X2 | ||||
STRING | XP_004157798.1 | 0.0 | (Cucumis sativus) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-128 | DP-E2F-like 1 |
Link Out ? help Back to Top | |
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Phytozome | Cucsa.098190.2 |
Publications ? help Back to Top | |||
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