PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.069440.2
Common NameCsa_6G312560, LOC101210138
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family ARR-B
Protein Properties Length: 644aa    MW: 71189.7 Da    PI: 5.6906
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.069440.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like84.61e-26190243155
         G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                     kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQ Y+l
  Cucsa.069440.2 190 KPRVVWSVELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQVYKL 243
                     79*******************.*******************************87 PP

2Response_reg72.31.9e-24121201109
                     EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTT CS
    Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaG 93 
                     vl+vdD+p+ +++l+++l++  y  v+ +  +e al +l+e++  +D++l D+ mp+mdG++ll++   e  +lp+i+++a + ++ + + +  G
  Cucsa.069440.2  12 VLVVDDDPTCLKILEKMLQNCCY-AVTKCNRAEIALSMLRENKngFDIVLSDVHMPDMDGFKLLEQVGLEM-DLPVIMMSADDGKNVVMKGVIHG 104
                     89*********************.***************999999**********************6644.8********************** PP

                     ESEEEESS--HHHHHH CS
    Response_reg  94 akdflsKpfdpeelvk 109
                     a d+l Kp+ +e+l++
  Cucsa.069440.2 105 ACDYLIKPVRIEALRN 120
                     *************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363922.7E-1621633IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23007.2E-419153No hitNo description
SuperFamilySSF521722.85E-349134IPR011006CheY-like superfamily
SMARTSM004484.2E-2710122IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.31711126IPR001789Signal transduction response regulator, receiver domain
PfamPF000727.3E-2212120IPR001789Signal transduction response regulator, receiver domain
CDDcd001561.83E-2513125No hitNo description
SuperFamilySSF466893.58E-18187246IPR009057Homeodomain-like
PROSITE profilePS5129412.254187246IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.7E-27189246IPR009057Homeodomain-like
TIGRFAMsTIGR015571.1E-23190244IPR006447Myb domain, plants
PfamPF002493.6E-7192242IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 644 aa     Download sequence    Send to blast
MSSDQFPAGL RVLVVDDDPT CLKILEKMLQ NCCYAVTKCN RAEIALSMLR ENKNGFDIVL  60
SDVHMPDMDG FKLLEQVGLE MDLPVIMMSA DDGKNVVMKG VIHGACDYLI KPVRIEALRN  120
LWQHVVRKRK TEWKDLEQSG SVDEGDREQN LSEGANYSSS AYEGSWNSSK RRRDAEEEPE  180
ERDDTSTLKK PRVVWSVELH QQFVAAVNQL GIDKAVPKKI LELMNVPGLT RENVASHLQV  240
YKLRLSGVSP HQSNLNNSFI NPQDPPFGSM GSFNGIDLQT LSVTGQLSPQ SLAALQATGL  300
RRPTAKSGIS MALDQNNIFS FENPKLRFVE DQTQHLNNSK PVNLFHGIPT KMEPKQLANI  360
QHPSVQPQGN INMQLNIKSE HGGTQLMHLS QQQTIGQTLG NSPASHLPRI SSTLRKPIIS  420
GSVMRGNGTA DNSHRPGYNL VSPTSVMVNY PMSQTTELSN NYSLQSNSSV STLNCKGMFQ  480
EEISSDLKVS GGLMSSYDVF SDLPLQKSHD WDSQNVSTLA FGTFHHGNFI QDSFDISSST  540
LIHHGFPSSQ TNGQNQNSSV VGKTVFSFSD STQPENPQNI FQNSLLDPVE VKSQRIPDAN  600
YQTDLLSEDF GQDELLGVFI KQQQQGDNGS VDFSGYQTEN ICV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A2e-20189249464ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6819240.0LN681924.1 Cucumis melo genomic scaffold, anchoredscaffold00047.
GenBankLN7132650.0LN713265.1 Cucumis melo genomic chromosome, chr_11.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004150083.10.0PREDICTED: two-component response regulator ARR2 isoform X1
SwissprotQ9ZWJ91e-169ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A0A0KF030.0A0A0A0KF03_CUCSA; Two-component response regulator
STRINGXP_004161384.10.0(Cucumis sativus)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-161response regulator 2
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  5. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  6. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  7. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  8. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  9. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  10. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  11. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  12. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]