PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID gw1.10.406.1
Common NameCOCSUDRAFT_7682
Organism
Coccomyxa subellipsoidea C-169
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Chlorophyta; Trebouxiophyceae; Trebouxiophyceae incertae sedis; Coccomyxaceae; Coccomyxa; Coccomyxa subellipsoidea
Family MYB
Protein Properties Length: 166aa    MW: 19424.1 Da    PI: 10.0802
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gw1.10.406.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding56.65.8e-181357348
                     SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                      WT+eEde l +av  +G ++Wk+Ia+++   Rt+ qc +rwqk+l
     gw1.10.406.1 13 GWTAEEDEVLRRAVSYYGAKNWKKIAEHFE-DRTDVQCLHRWQKVL 57
                     6*****************************.************986 PP
2Myb_DNA-binding66.35.6e-2163109148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+WT+eEd++++++v++lG ++W++Ia+ ++ gR +kqc++rw+++l
     gw1.10.406.1  63 KGPWTPEEDLKIIELVTRLGAKRWSLIAKDLP-GRIGKQCRERWHNHL 109
                      79******************************.*************97 PP
3Myb_DNA-binding59.76.4e-19115159147
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                      rg WT+eEd  lv+ ++++G+  W++Ia+ ++ gRt++ +k++w++ 
     gw1.10.406.1 115 RGDWTKEEDSMLVEKHAEYGNQ-WAKIAQFLP-GRTDNAIKNHWNST 159
                      899*****************99.*********.***********986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129417.864157IPR017930Myb domain
SMARTSM007178.5E-151059IPR001005SANT/Myb domain
SuperFamilySSF466893.19E-181267IPR009057Homeodomain-like
PfamPF002496.5E-161257IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.607.1E-241373IPR009057Homeodomain-like
CDDcd001678.17E-131457No hitNo description
PROSITE profilePS5129431.47558113IPR017930Myb domain
SuperFamilySSF466893.1E-3360156IPR009057Homeodomain-like
SMARTSM007173.0E-1762111IPR001005SANT/Myb domain
PfamPF002492.2E-1963109IPR001005SANT/Myb domain
CDDcd001677.33E-1465109No hitNo description
Gene3DG3DSA:1.10.10.602.5E-2974116IPR009057Homeodomain-like
SMARTSM007172.7E-18114162IPR001005SANT/Myb domain
PROSITE profilePS5129424.11114164IPR017930Myb domain
PfamPF002494.1E-17115158IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.8E-25117164IPR009057Homeodomain-like
CDDcd001671.11E-11118157No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032875Biological Processregulation of DNA endoreduplication
GO:0003677Molecular FunctionDNA binding
GO:0003713Molecular Functiontranscription coactivator activity
Sequence ? help Back to Top
Protein Sequence    Length: 166 aa     Download sequence    Send to blast
KTGAPTRRSA VGGWTAEEDE VLRRAVSYYG AKNWKKIAEH FEDRTDVQCL HRWQKVLNPE  60
LVKGPWTPEE DLKIIELVTR LGAKRWSLIA KDLPGRIGKQ CRERWHNHLD PTIKRGDWTK  120
EEDSMLVEKH AEYGNQWAKI AQFLPGRTDN AIKNHWNSTM RRKVES
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C4e-72121649159MYB PROTO-ONCOGENE PROTEIN
1h89_C4e-72121649159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250|UniProtKB:Q94FL9, ECO:0000269|PubMed:26069325}.
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269|PubMed:20018666}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00505DAPTransfer from AT5G11510Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269|PubMed:16463103}.
UniProtINDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17287251}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_005647035.11e-120Homeodomain-like protein, partial
SwissprotQ6R0324e-79MB3R5_ARATH; Transcription factor MYB3R-5
SwissprotQ94FL97e-77MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBLI0YVS21e-119I0YVS2_COCSC; Homeodomain-like protein (Fragment)
STRINGXP_005647035.11e-120(Coccomyxa subellipsoidea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
ChlorophytaeOGCP1516114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02320.22e-81myb domain protein 3r-5
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Blanc G, et al.
    The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation.
    Genome Biol., 2012. 13(5): p. R39
    [PMID:22630137]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Saito T, et al.
    Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana.
    Plant Signal Behav, 2015. 10(3): p. e990817
    [PMID:25806785]
  5. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  6. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]