PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK21687.3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family MYB_related
Protein Properties Length: 650aa    MW: 72303.8 Da    PI: 9.1952
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK21687.3genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding22.92e-07551600147
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT...TTS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmg...kgRtlkqcksrwqky 47 
                      r +++  E e lv+av++lG+g+W+ +  +     k+Rt  ++k++w ++
        PK21687.3 551 RRPFSVTEVEALVEAVEELGTGRWRDVKLRAFdnaKHRTYVDLKDKWKTL 600
                      678999********************9988889**************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF542362.02E-5353433IPR029071Ubiquitin-related domain
PROSITE profilePS5129415.496546605IPR017930Myb domain
SMARTSM007173.7E-7550603IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.606.2E-10551601IPR009057Homeodomain-like
SuperFamilySSF466895.38E-15552633IPR009057Homeodomain-like
CDDcd116603.73E-16552602No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 650 aa     Download sequence    Send to blast
MVLKKRLEYG FHGFQVPTIP RAPRSARRRG PNKKKTEDSQ ICAFELLASL AGKLLQESES  60
SSACSNASEG NHRSFDEDVI KHERHAEDTL LKEECFDQGS SEESAFASEI SSQNIGQKLL  120
SKRFLHSERD VVSERTSTRA DLVNVIPTFH NCPPKVETGT LSKANLCNSK DPMELQVEFP  180
TMVNLENDVK LPSLREHVSN ASFSKHRNDI KLVGRDDDEN CAGQNKSSTK VKAFRPSVRI  240
GDRKIRKLLT SKYWKVAPKL RDCESFRSDG GMKPLYNKRK SCYSRDRYQH NTFYKRRKLF  300
DRGSVVLSDG GFSSESVSNS PEKGKSGEKN GFNGMLHGAG VSSSVISRQG SFHSKDSHVK  360
LSIKSFKIPE LFIEVPETAT IGSLRRTVME TVTAILGGGL HVGVLLQGKK VKDDNKTLHQ  420
TGISCKDNLD GLGFTLEPNT MPASPSIYTD DPLPSLSCDE PETLRSLGAP LVDSVISDAL  480
FETTLPSTNT GALVESNLES VSCHNDSLTD NIMSDSRALV VVPAISMEAL AVVPANKKSK  540
RSSELAQRRT RRPFSVTEVE ALVEAVEELG TGRWRDVKLR AFDNAKHRTY VDLKDKWKTL  600
VHTARISPQQ RRGEPVPQDL LDRVLTAHAY WSQHQAKQQL KQQPETCLLL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2juh_A2e-575346411107Telomere binding protein TBP1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1277297KRKSCYSRDRYQHNTFYKRRK
Functional Description ? help Back to Top
Source Description
UniProtBinds specifically to the plant telomeric double-stranded DNA sequences 5'-TTTAGGG-3'. At least 2 repeats of telomeric sequences are required for binding. Induces DNA bending. {ECO:0000269|PubMed:11513850, ECO:0000269|PubMed:17272298}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salt stress. {ECO:0000269|PubMed:12909688}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024021528.10.0telomere repeat-binding protein 4 isoform X2
SwissprotQ9FFY91e-176TRP4_ARATH; Telomere repeat-binding protein 4
TrEMBLA0A2P5B7K10.0A0A2P5B7K1_PARAD; Octamer-binding transcription factor
STRINGXP_010096584.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF13562844
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G07540.14e-98TRF-like 2
Publications ? help Back to Top
  1. Zentgraf U,Hinderhofer K,Kolb D
    Specific association of a small protein with the telomeric DNA-protein complex during the onset of leaf senescence in Arabidopsis thaliana.
    Plant Mol. Biol., 2000. 42(3): p. 429-38
    [PMID:10798613]
  2. Hwang MG,Chung IK,Kang BG,Cho MH
    Sequence-specific binding property of Arabidopsis thaliana telomeric DNA binding protein 1 (AtTBP1).
    FEBS Lett., 2001. 503(1): p. 35-40
    [PMID:11513850]
  3. Hwang MG,Cho MH
    Arabidopsis thaliana telomeric DNA-binding protein 1 is required for telomere length homeostasis and its Myb-extension domain stabilizes plant telomeric DNA binding.
    Nucleic Acids Res., 2007. 35(4): p. 1333-42
    [PMID:17272298]
  4. Fulcher N,Riha K
    Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana.
    Front Genet, 2015. 6: p. 349
    [PMID:26779251]