PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK13777.1
Organism
Cannabis sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family C2H2
Protein Properties Length: 374aa    MW: 42994.7 Da    PI: 6.5076
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK13777.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.80.0007379101323
                ET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                C+   Cgk+F +   Lk+H   H
  PK13777.1  79 CSyeSCGKTFIDAGALKKHSHIH 101
                77779**************7766 PP
2zf-C2H216.52.4e-05106130123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                y+C+   Cgk F ++s LkrH   H
  PK13777.1 106 YVCHyeGCGKKFLDSSKLKRHFLIH 130
                9********************8877 PP
3zf-C2H221.75.3e-07136160123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                ++Cp   Cgk Fs   nL++H++tH
  PK13777.1 136 FVCPheGCGKAFSLDFNLRSHMKTH 160
                89**********************9 PP
4zf-C2H216.81.9e-05166190123
                EEET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                + Cp  dCgk++ + + Lk+Hi++H
  PK13777.1 166 HICPyqDCGKRYAHEYKLKNHISSH 190
                68**********************6 PP
5zf-C2H215.54.9e-05231256123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                y Cp   C+k + + + Lk H+r+ H
  PK13777.1 231 YACPyeGCDKAYIHEYKLKLHLRReH 256
                89**********************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.6E-1272103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.04277101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.01177106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576672.75E-880130No hitNo description
Gene3DG3DSA:3.30.160.602.3E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.921106135IPR007087Zinc finger, C2H2
SMARTSM003550.0024106130IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576671.91E-14117170No hitNo description
Gene3DG3DSA:3.30.160.603.5E-20127160IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003553.1E-4136160IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.695136165IPR007087Zinc finger, C2H2
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.4E-8161192IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.203166195IPR007087Zinc finger, C2H2
SMARTSM003550.011166190IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
SuperFamilySSF576671.19E-5226254No hitNo description
Gene3DG3DSA:3.30.160.602.6E-9226254IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.138231261IPR007087Zinc finger, C2H2
SMARTSM003550.0038231256IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280233256IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
METHFNHNLF ERRPILRSKT PAVKWFREWV PQDVVATGGK CFLYKWVTED TLKSLEEKAK  60
EPEVPEPEPE PTTEVLFLCS YESCGKTFID AGALKKHSHI HGERQYVCHY EGCGKKFLDS  120
SKLKRHFLIH TGERDFVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY QDCGKRYAHE  180
YKLKNHISSH HEKSGTVDVT KFTPTPPPEK PARTPKPSAG VYGSASSDRP YACPYEGCDK  240
AYIHEYKLKL HLRREHPGHT SDENVENPAI NTAHEIDEGS DQDAYGGNRM HNGKSQKQSR  300
PKPSVKLPPA KIAQRKGSTP PPARVNIVKK PWSVKDEVYE EDSEETEEDR DNIEDGWRYA  360
EQNEDDDEET EYED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-33791908119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010087411.10.0zinc finger transcription factor YY1
SwissprotQ2V3L31e-160YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A2P5EEF10.0A0A2P5EEF1_TREOI; TFIIH C1-like domain containing protein
STRINGXP_010087411.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-146C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]