PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK12852.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

C2H2

Protein Properties

Length: 1586aa MW: 175568 Da PI: 6.5244

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK12852.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.6	0.00087	1557	1583	1	23
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 y+C+ Cg sF+ s++ rH r+ H PK12852.1 1557 YQCKidGCGLSFRFVSDFSRHRRKtgH 1583 99*********************9777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00545	1.9E-13	15	55	IPR003349	JmjN domain
PROSITE profile	PS51183	13.398	16	57	IPR003349	JmjN domain
Pfam	PF02375	3.6E-14	17	50	IPR003349	JmjN domain
SMART	SM00558	5.3E-44	287	456	IPR003347	JmjC domain
SuperFamily	SSF51197	5.49E-27	288	453	No hit	No description
PROSITE profile	PS51184	33.942	290	456	IPR003347	JmjC domain
Pfam	PF02373	2.5E-36	320	439	IPR003347	JmjC domain
SMART	SM00355	44	1474	1496	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	0.62	1497	1521	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	11.78	1497	1526	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	5.01E-5	1497	1534	No hit	No description
Gene3D	G3DSA:3.30.160.60	3.6E-4	1498	1525	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	1499	1521	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	6.2E-10	1526	1551	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.946	1527	1556	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0018	1527	1551	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1529	1551	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.95E-10	1537	1579	No hit	No description
Gene3D	G3DSA:3.30.160.60	9.9E-11	1552	1580	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	9.577	1557	1586	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.16	1557	1583	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	1559	1583	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009741	Biological Process	response to brassinosteroid
GO:0009826	Biological Process	unidimensional cell growth
GO:0033169	Biological Process	histone H3-K9 demethylation
GO:0048577	Biological Process	negative regulation of short-day photoperiodism, flowering
GO:0048579	Biological Process	negative regulation of long-day photoperiodism, flowering
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 1586 aa Download sequence Send to blast
MGNVEIPKWL EGLPLAPEFH PTDTEFADPI AYISKIEKEA GAFGICKIIP PLPKPSKKYV 60 FNNLNKSLLK SPELGSHGNS VNNHSLSKTA SLDGSNGEEV RAVFTTRQQE LGQNVKKAKG 120 AVQNPPPSVH KQVWQSGEIY TLEQFETKSR AFAKSQLGMI KEVSPLVIEA MFWKAASEKP 180 MYVEYANDVP GSGFGEPEGQ FRYFHRRRRK RNSYHRSREG SNCKNNEVVT NGIVVSNTNA 240 DASHINGSDV CETPTSIPMN PLNGTSQSSK KKSQYSSCEK EGSAGWKLSN SPWNLQVISR 300 SPGSLTRFMP DDIPGVTSPM VYIGMLFSWF AWHVEDHELH SMNYLHTGSS KTWYAVPGDY 360 AFAFEEVVRS EAYGGDIDHL AALTLLGEKT TLVSPEVVVA SNIPCCRLIQ NPGEFVVTFP 420 RAYHVGFSHG FNCGEAANFG TPQWLKVAKE AAVRRAAMNY LPMLSHQQLL YLLTMSFMSR 480 VPRSLLPGVR SSRLKDRLKE GREFLVKKAF IEDILNENNT LSIVLQKDSR YRAVLWNPDI 540 LTYPSKETLA PTAGAIVSTS STATENTPLD YRKHDNEQNN LLDEMNLYME NLNDLYLGSD 600 DLSCDLQVDS GALACVACGI LGFPFMSVVQ PSEKASLELL HDNHLLFQEC PGGYLNCFSS 660 LDLDVSNNAS ITENVSTVSN PPSMDLPVPS VNKFDGGQNA YNKFLRPRSF CLEHAVEIID 720 ILQGIGGAEV LVICHSDYQK IKAHAAAIAE EIGSPFNYKE VPLDIASKDD LNLIDIAIDD 780 EHDECGKDWT SKLGINLQHC IKVRRNSSSK QVRHALTLGG LFSDKPSSQD FSPLKWQLRR 840 SRSKKIYVKP FDSAQVKKVV GETSSTIEKE KKLIQYSRRK FNRKPGGLTG AGKFCGQHAK 900 GGDLDELAKR ASETGNDVGN STSCKFSALI KISETHNENQ TSEATWNNSM KASCGSVENQ 960 VLKEMNLDSQ ACLVASSDAS KMQDESSVPT QKVSITDKLV EKLEACPFSH DTKESSGLLG 1020 DQLKVGQSNK TDGANVDSEG HSNVKAGKEG VLTDLNSDLS NMTNSHAIES QDDNLMGQIK 1080 NAVVENVSMT VEVCDSVSVD KEVTLVVHAT RIDDGEPVSC NSTVIIDNIG TSKEECFNCS 1140 GEICSVEDPS SNGKALKVES EEEIKTRINK YPLASVEETS KAWSETHSTK DFSETIPVLI 1200 EETSEFLSDP SSAAKLCCAV ASEQILKQKV GTSDGSSEEL ASSSVTQMEV HHRHCVSIEE 1260 HSDVLRESSV EDDLGTDVTS DNGFHKEASM KNGEQRSVSP VTQTVDQPTP ISVGESETPW 1320 NPSKEHPGDG LTLDDKKRKS ETTALPNSIS FQKCSRVRRE THTNEDLCNG SEVCSSQDDR 1380 ALDSESKDID TCSNPVKGRK RKKEIELLTE NQFSCNGFTR SPCEGLRPRT LKDATSCETD 1440 TLREVERKPA VKVKKTSNVR GPPKDKKENS RKPHKCDLES CRMSFDTKAE LMLHKRNRCP 1500 HEGCGKRFSS HKYAMIHHRV HDDQRPLKCP WEGCSMSFKW AWARTEHIRV HTGERPYQCK 1560 IDGCGLSFRF VSDFSRHRRK TGHYVN

Sequence ? help Back to Top

Protein Sequence Length: 1586 aa Download sequence Send to blast

MGNVEIPKWL EGLPLAPEFH PTDTEFADPI AYISKIEKEA GAFGICKIIP PLPKPSKKYV  60
FNNLNKSLLK SPELGSHGNS VNNHSLSKTA SLDGSNGEEV RAVFTTRQQE LGQNVKKAKG  120
AVQNPPPSVH KQVWQSGEIY TLEQFETKSR AFAKSQLGMI KEVSPLVIEA MFWKAASEKP  180
MYVEYANDVP GSGFGEPEGQ FRYFHRRRRK RNSYHRSREG SNCKNNEVVT NGIVVSNTNA  240
DASHINGSDV CETPTSIPMN PLNGTSQSSK KKSQYSSCEK EGSAGWKLSN SPWNLQVISR  300
SPGSLTRFMP DDIPGVTSPM VYIGMLFSWF AWHVEDHELH SMNYLHTGSS KTWYAVPGDY  360
AFAFEEVVRS EAYGGDIDHL AALTLLGEKT TLVSPEVVVA SNIPCCRLIQ NPGEFVVTFP  420
RAYHVGFSHG FNCGEAANFG TPQWLKVAKE AAVRRAAMNY LPMLSHQQLL YLLTMSFMSR  480
VPRSLLPGVR SSRLKDRLKE GREFLVKKAF IEDILNENNT LSIVLQKDSR YRAVLWNPDI  540
LTYPSKETLA PTAGAIVSTS STATENTPLD YRKHDNEQNN LLDEMNLYME NLNDLYLGSD  600
DLSCDLQVDS GALACVACGI LGFPFMSVVQ PSEKASLELL HDNHLLFQEC PGGYLNCFSS  660
LDLDVSNNAS ITENVSTVSN PPSMDLPVPS VNKFDGGQNA YNKFLRPRSF CLEHAVEIID  720
ILQGIGGAEV LVICHSDYQK IKAHAAAIAE EIGSPFNYKE VPLDIASKDD LNLIDIAIDD  780
EHDECGKDWT SKLGINLQHC IKVRRNSSSK QVRHALTLGG LFSDKPSSQD FSPLKWQLRR  840
SRSKKIYVKP FDSAQVKKVV GETSSTIEKE KKLIQYSRRK FNRKPGGLTG AGKFCGQHAK  900
GGDLDELAKR ASETGNDVGN STSCKFSALI KISETHNENQ TSEATWNNSM KASCGSVENQ  960
VLKEMNLDSQ ACLVASSDAS KMQDESSVPT QKVSITDKLV EKLEACPFSH DTKESSGLLG  1020
DQLKVGQSNK TDGANVDSEG HSNVKAGKEG VLTDLNSDLS NMTNSHAIES QDDNLMGQIK  1080
NAVVENVSMT VEVCDSVSVD KEVTLVVHAT RIDDGEPVSC NSTVIIDNIG TSKEECFNCS  1140
GEICSVEDPS SNGKALKVES EEEIKTRINK YPLASVEETS KAWSETHSTK DFSETIPVLI  1200
EETSEFLSDP SSAAKLCCAV ASEQILKQKV GTSDGSSEEL ASSSVTQMEV HHRHCVSIEE  1260
HSDVLRESSV EDDLGTDVTS DNGFHKEASM KNGEQRSVSP VTQTVDQPTP ISVGESETPW  1320
NPSKEHPGDG LTLDDKKRKS ETTALPNSIS FQKCSRVRRE THTNEDLCNG SEVCSSQDDR  1380
ALDSESKDID TCSNPVKGRK RKKEIELLTE NQFSCNGFTR SPCEGLRPRT LKDATSCETD  1440
TLREVERKPA VKVKKTSNVR GPPKDKKENS RKPHKCDLES CRMSFDTKAE LMLHKRNRCP  1500
HEGCGKRFSS HKYAMIHHRV HDDQRPLKCP WEGCSMSFKW AWARTEHIRV HTGERPYQCK  1560
IDGCGLSFRF VSDFSRHRRK TGHYVN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6ip0_A	9e-59	277	470	144	346	Transcription factor jumonji (Jmj) family protein
6ip4_A	9e-59	277	470	144	346	Arabidopsis JMJ13
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	1398	1402	RKRKK
2	1398	1403	RKRKKE

Functional Description ? help Back to Top
Source	Description
UniProt	Acts probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269\|PubMed:15377760, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19946624}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024031706.1	0.0	probable lysine-specific demethylase ELF6
Swissprot	Q6BDA0	0.0	ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBL	A0A2P5D421	0.0	A0A2P5D421_TREOI; TFIIH C1-like domain containing protein
STRING	XP_010112224.1	0.0	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8031	30	34

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G04240.1	0.0	C2H2 family protein

Publications ? help Back to Top
Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A. PLoS ONE, 2013. 8(7): p. e67987 [PMID:23976921] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Crevillén P, et al. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature, 2014. 515(7528): p. 587-90 [PMID:25219852] Yang H,Howard M,Dean C Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74 [PMID:27482092]