PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK12669.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family ARF
Protein Properties Length: 525aa    MW: 58336.1 Da    PI: 6.6959
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK12669.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B371.31.2e-22113213198
                EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..E CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelv 93 
                f+k+lt sd++++g +++ +++a+++       +++    ++l+ +d++g++W +++i+r++++r++lt+GW+ Fv++++L +gD ++F   + +++el+
  PK12669.1 113 FCKTLTASDTSTHGGFSVLRRHADDClppldmsQQP--PWQELVATDLHGNEWHFRHIFRGQPRRHLLTTGWSVFVSSKKLVAGDAFIFL--RGENGELR 208
                99****************************964333..4459************************************************..449999** PP

                EEEE- CS
         B3  94 vkvfr 98 
                v+v+r
  PK12669.1 209 VGVRR 213
                ***97 PP

2Auxin_resp110.12.3e-36239321183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 a+ha+st++ F+v+Y+Pr+s+seF v+v+k+++a ++k+svGmRfkm+fe+e+++err+sGt+vgv d  ++ W +S+WrsLk
   PK12669.1 239 ASHAISTGTLFSVFYKPRTSRSEFLVSVNKYLEAHNQKLSVGMRFKMRFEGEEVPERRFSGTIVGVGDNTSSGWAHSEWRSLK 321
                 789******************************************************************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.44E-43102242IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.1E-40109228IPR015300DNA-binding pseudobarrel domain
CDDcd100174.06E-21111213No hitNo description
SMARTSM010191.0E-21113215IPR003340B3 DNA binding domain
PROSITE profilePS5086311.279113215IPR003340B3 DNA binding domain
PfamPF023621.8E-20113213IPR003340B3 DNA binding domain
PfamPF065072.1E-34239321IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009733Biological Processresponse to auxin
GO:0010150Biological Processleaf senescence
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0042802Molecular Functionidentical protein binding
Sequence ? help Back to Top
Protein Sequence    Length: 525 aa     Download sequence    Send to blast
XPVSSDELYK ELWHACAGPL VTLPREGQRV YYFPQGHMEQ LEASMHQGLE QQMPSFNLPS  60
KILCKVVNVQ LRAEVETDEV YAQITLLPEQ DQTELTSPDP PLPEPPRCTV HSFCKTLTAS  120
DTSTHGGFSV LRRHADDCLP PLDMSQQPPW QELVATDLHG NEWHFRHIFR GQPRRHLLTT  180
GWSVFVSSKK LVAGDAFIFL RGENGELRVG VRRLMRQPSN MPSSVISSHS MHLGVLATAS  240
HAISTGTLFS VFYKPRTSRS EFLVSVNKYL EAHNQKLSVG MRFKMRFEGE EVPERRFSGT  300
IVGVGDNTSS GWAHSEWRSL KVQWDEPSSI MRPERVSPWE LEPLVATPPP TTQPTQRNKR  360
ARPSVLPPPS SDLSALGTWK SLGDSPSAFS YCDQQRGQEL YSSPKFSSAS KSSSLGFSGN  420
NNLATMSSNT MYWSNRVDAV TDSFSIYKDA GERKQNSGSS CRLFGIQLVH NSNLEDTSPV  480
QVVAMAGSFG DALPVPSLDA ESEHSEPSNV NRADHPSVSY DAEKS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A0.0334414355Auxin response factor 1
4ldw_A0.0334414355Auxin response factor 1
4ldw_B0.0334414355Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16176952}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00097PBMTransfer from AT1G59750Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024023552.10.0auxin response factor 1
RefseqXP_024023553.10.0auxin response factor 1
SwissprotQ8L7G00.0ARFA_ARATH; Auxin response factor 1
TrEMBLA0A2P5D5I90.0A0A2P5D5I9_TREOI; Auxin response factor
STRINGXP_009355376.10.0(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF68022638
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G59750.40.0auxin response factor 1
Publications ? help Back to Top
  1. Montesinos JC,Pastor-Cantizano N,Robinson DG,Marcote MJ,Aniento F
    Arabidopsis p24δ5 and p24δ9 facilitate Coat Protein I-dependent transport of the K/HDEL receptor ERD2 from the Golgi to the endoplasmic reticulum.
    Plant J., 2014. 80(6): p. 1014-30
    [PMID:25312353]
  2. Marais C, et al.
    The Qb-SNARE Memb11 interacts specifically with Arf1 in the Golgi apparatus of Arabidopsis thaliana.
    J. Exp. Bot., 2015. 66(21): p. 6665-78
    [PMID:26208648]
  3. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  4. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]