PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK12001.1
Organism
Cannabis sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family MIKC_MADS
Protein Properties Length: 190aa    MW: 21831.9 Da    PI: 10.2146
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK12001.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF953.4e-30959151
               S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
     SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
               krien   rqvtfskRrng+lKKA+ELSvLCdaeva+iifs++gklye++s
  PK12001.1  9 KRIENAASRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSPRGKLYEFAS 59
               79***********************************************86 PP
2K-box70.93.9e-2490182799
      K-box   7 ksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkle 99 
                 + ++ +a+ +++++  + k+i+ L+ ++ +llG++Les+s++eL+q+e+qLe+sl kiR++Kn+l++eqie+l++ ek+l e+n +Lr++++
  PK12001.1  90 DDHHDLQAAVSKEDSFSMAKKIDHLEVSKMKLLGDGLESCSFQELHQIENQLERSLAKIRARKNQLYREQIEKLKQEEKSLLEHNAKLRQQVQ 182
                44677777888899999*************************************************************************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006631.609161IPR002100Transcription factor, MADS-box
SMARTSM004328.3E-41160IPR002100Transcription factor, MADS-box
CDDcd002654.10E-41371No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
SuperFamilySSF554554.45E-32374IPR002100Transcription factor, MADS-box
PRINTSPR004046.4E-31323IPR002100Transcription factor, MADS-box
PfamPF003196.7E-271057IPR002100Transcription factor, MADS-box
PRINTSPR004046.4E-312338IPR002100Transcription factor, MADS-box
PRINTSPR004046.4E-313859IPR002100Transcription factor, MADS-box
PfamPF014863.0E-2396181IPR002487Transcription factor, K-box
PROSITE profilePS5129713.99497189IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 190 aa     Download sequence    Send to blast
MVRGKTQMKR IENAASRQVT FSKRRNGLLK KAFELSVLCD AEVALIIFSP RGKLYEFASS  60
SINKTIERYT QRRTKDGGSC LTSNKTISQD DHHDLQAAVS KEDSFSMAKK IDHLEVSKMK  120
LLGDGLESCS FQELHQIENQ LERSLAKIRA RKNQLYREQI EKLKQEEKSL LEHNAKLRQQ  180
VQCGMLQKVX
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A1e-20171171MEF2C
5f28_B1e-20171171MEF2C
5f28_C1e-20171171MEF2C
5f28_D1e-20171171MEF2C
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner. {ECO:0000269|PubMed:16778081}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Maintained at very low levels by the polycomb-group (PcG) proteins MSI1, CLF, and EMF2 via histone methylation (H3K27me3). Derepressed upon cold treatment (vernalization). {ECO:0000269|PubMed:16778081}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024029068.15e-96agamous-like MADS-box protein AGL14 isoform X1
RefseqXP_024029069.15e-96agamous-like MADS-box protein AGL14 isoform X2
SwissprotO827434e-70AGL19_ARATH; Agamous-like MADS-box protein AGL19
TrEMBLA0A2P5CSN31e-100A0A2P5CSN3_TREOI; MADS-box transcription factor
STRINGEOY245832e-80(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66630102
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G11880.14e-65AGAMOUS-like 14
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Suter L,Rüegg M,Zemp N,Hennig L,Widmer A
    Gene regulatory variation mediates flowering responses to vernalization along an altitudinal gradient in Arabidopsis.
    Plant Physiol., 2014. 166(4): p. 1928-42
    [PMID:25339407]