PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK10562.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

bHLH

Protein Properties

Length: 555aa MW: 60810.6 Da PI: 8.5497

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK10562.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	56.3	5.7e-18	265	314	2	55
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r +h++ E+rRR++iN++f++Lrel+P+ ++K +Ka+ L +++eYI++Lq PK10562.1 265 RSKHSATEQRRRSKINDRFQRLRELIPNI----DQKRDKASFLLEVIEYIQYLQ 314 889***********************6....69****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	1.4E-23	260	335	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	17.346	263	313	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.45E-19	263	340	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.8E-15	265	314	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	9.11E-16	265	318	No hit	No description
SMART	SM00353	1.8E-13	269	319	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:0009742	Biological Process	brassinosteroid mediated signaling pathway
GO:1902448	Biological Process	positive regulation of shade avoidance
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 555 aa Download sequence Send to blast
MELSQPRPYG TEGRKPTHDF LSLYNHSTAQ QDPRPASQGG YLKTHDFLQP LERVGKATCA 60 KEETSVEIST SEKPPPPAPP PVEHVLPGGI GTYSISHISY FNQIQSRVPK PEGMVYPAAQ 120 ASSTDKNDEN SNCSSFTGSG FTLWEEPAVK KGKTGKENMV VDKPGVVEPV ARVGQWASTE 180 RPSQSSSSNH RGSFSSLSSS QPSAQRNQSF MEMIKSAKGC SQDDEIEEED QYILKKEIST 240 GTAQRGELRV KVDGKSSDQK ANTPRSKHSA TEQRRRSKIN DRFQRLRELI PNIDQKRDKA 300 SFLLEVIEYI QYLQEKVHKH EGSFQGWANE PAKLMPWRNN HRLGEAFDHS QGLNGVSGPP 360 LVFASKFEKH ATAIPKAPGN AQHLVESDIS TTTVTNKGVT IPMSLQPNFF LPNGGASSHC 420 PPRLPSDLEN RSFQPQSQLC QTRSCTTVDG SIASDKLKEE ELTIEGGTIS ISTAYSQGLL 480 DTLTQALQHS GVDLSQASIS VQIELGKRAS SRTTASTSTT KDKEIPSSNQ GIKHSRVASV 540 NDSDQAQKKL KTSKN

Sequence ? help Back to Top

Protein Sequence Length: 555 aa Download sequence Send to blast

MELSQPRPYG TEGRKPTHDF LSLYNHSTAQ QDPRPASQGG YLKTHDFLQP LERVGKATCA  60
KEETSVEIST SEKPPPPAPP PVEHVLPGGI GTYSISHISY FNQIQSRVPK PEGMVYPAAQ  120
ASSTDKNDEN SNCSSFTGSG FTLWEEPAVK KGKTGKENMV VDKPGVVEPV ARVGQWASTE  180
RPSQSSSSNH RGSFSSLSSS QPSAQRNQSF MEMIKSAKGC SQDDEIEEED QYILKKEIST  240
GTAQRGELRV KVDGKSSDQK ANTPRSKHSA TEQRRRSKIN DRFQRLRELI PNIDQKRDKA  300
SFLLEVIEYI QYLQEKVHKH EGSFQGWANE PAKLMPWRNN HRLGEAFDHS QGLNGVSGPP  360
LVFASKFEKH ATAIPKAPGN AQHLVESDIS TTTVTNKGVT IPMSLQPNFF LPNGGASSHC  420
PPRLPSDLEN RSFQPQSQLC QTRSCTTVDG SIASDKLKEE ELTIEGGTIS ISTAYSQGLL  480
DTLTQALQHS GVDLSQASIS VQIELGKRAS SRTTASTSTT KDKEIPSSNQ GIKHSRVASV  540
NDSDQAQKKL KTSKN

Functional Description ? help Back to Top
Source	Description
UniProt	Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269\|PubMed:15680330}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00498	DAP	Transfer from AT5G08130	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by cold treatment. {ECO:0000269\|PubMed:12679534}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024024837.1	0.0	transcription factor BIM1 isoform X2
Swissprot	Q9LEZ3	1e-127	BIM1_ARATH; Transcription factor BIM1
TrEMBL	A0A2P5EBR7	0.0	A0A2P5EBR7_TREOI; Basic helix-loop-helix transcription factor
STRING	XP_010101635.1	0.0	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7252	31	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08130.4	1e-123	bHLH family protein

Publications ? help Back to Top
Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]