PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10022932m
Common NameCARUB_v10022932mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family E2F/DP
Protein Properties Length: 555aa    MW: 60787.2 Da    PI: 6.4653
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10022932mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP81.95.4e-26234299171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      r+++sL+llt+kf++l++++++g+++ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  Carubv10022932m 234 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 299
                      6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.7E-28230301IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.04E-16234297IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.2E-32234299IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.1E-22236299IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.54E-32312416No hitNo description
CDDcd146602.55E-49312416No hitNo description
PfamPF164219.8E-33315414IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 555 aa     Download sequence    Send to blast
FPPHLSQHKI PSFPRFLLSS SLFFFSFFVL LLPPPSLSIT KTLVFFNRRR SSLHRNLTNP  60
THVSLRSMSG LVRSSSGSSQ PPPPPPHHPP SSSAPVTSTP VVPPIRRHLA FASTKPPFHP  120
SDDYHRFTPS LTNNSDRSFI NGCGVVDREE DAVVVRSPSR KRKSTMDVVV APCNNGFTTS  180
SGFTSIPSSP CRTPSKAGRV NIKSKAKGNK SAPQTPISTN TGSPVTLTPS GSCRYDSSLG  240
LLTKKFVNLI KQAKDGMLDL NKAAETLEVQ KRRIYDITNV LEGIDLIEKP FKNRILWKGV  300
DASSPDDVDA DVSVLQAEIE NLSLQEQALD NQIRQSEERL RDLSENEKNQ KWLFVTEEDI  360
KSLPGFQNQT LIAVKAPHGT TLEVPDPDEA VDHPQRRYRI ILRSTMGPID VYLVSEFEGK  420
FEDTNGSVPA PPACLPIASS SGSTGHHDIE ALTVNNTGNA IEHQVSHDHA HPQPGDTSDL  480
NYLQEQVGGM LKITPSDIEN DESDYWLLSN AEISMTDIWK TDSGIDWDYG IADVGTPPPV  540
MGEIAPTAVD STPR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-23229300274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1158163SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10022932m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2425820.0AF242582.1 Arabidopsis thaliana E2F transcription factor-3 E2F3 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006293941.20.0transcription factor E2FA
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLR0HBL70.0R0HBL7_9BRAS; Uncharacterized protein (Fragment)
STRINGXP_006293941.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.30.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]