PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10018365m
Common NameCARUB_v10018365mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family E2F/DP
Protein Properties Length: 400aa    MW: 45028.2 Da    PI: 8.8282
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10018365mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.21.4e-233297171
          E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                     rk+ksL+ll+++fl+l+++   +++ l+++a++L    v  +rRRiYDi+NVLe+++++++++kn+++wkg
  Carubv10018365m 32 RKQKSLGLLCTNFLALYNRDGIEMIGLDDAASKL---GV--ERRRIYDIVNVLESVGVLTRRAKNQYTWKG 97
                     79*****************999************...**..****************************98 PP
2E2F_TDP794.3e-25167247171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                      r+eksL+lltq+f+kl+ +se++i++l+e+ak L+ +      +++k+RR+YDi+NVL+++nliek     ++k++++w g
  Carubv10018365m 167 RREKSLGLLTQNFIKLFVCSEARIISLEEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMNLIEKtqtldSRKPAFKWLG 247
                      689**************************************999**********************999999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-262898IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.53E-163195IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.6E-283297IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.3E-203397IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.4E-22165248IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.2E-31167247IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.82E-14169248IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023195.5E-20169247IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 400 aa     Download sequence    Send to blast
MSDLPPERSK MVVYSPSSMS ETSSALHHSY SRKQKSLGLL CTNFLALYNR DGIEMIGLDD  60
AASKLGVERR RIYDIVNVLE SVGVLTRRAK NQYTWKGFAA IPGALKELQE EGVKDTFHRF  120
YVNENVKGSD DEDDDEESSQ PHSSSQTDSS KPGSLPQSSD LSKIDNRREK SLGLLTQNFI  180
KLFVCSEARI ISLEEAAKLL LGDAHNTSIM RTKVRRLYDI ANVLSSMNLI EKTQTLDSRK  240
PAFKWLGYNG EPTFTLSSDL MQIESRKRAF GTDLTNVNVK RSKSSSSSQE NATERRVKMK  300
KHSTPESSYN KSFDAHEARH GSRGYQFGPF APGSGTYSTA GLEDSSRRAF DVENLVSDYH  360
PSYQNQVLKD LFSHYMDAWK TWYTEVTQKN PLPNTSQHR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A8e-40312393228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10018365m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0745330.0AB074533.1 Arabidopsis thaliana mRNA for E2F-like repressor E2L3, complete cds.
GenBankBT0042580.0BT004258.1 Arabidopsis thaliana clone RAFL15-19-A14 (R20743) putative DP-E2F protein 1 (At3g48160) mRNA, complete cds.
GenBankBT0055240.0BT005524.1 Arabidopsis thaliana clone U20743 putative DP-E2F protein 1 (At3g48160) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006292160.10.0E2F transcription factor-like E2FE isoform X2
SwissprotQ8LSZ40.0E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLR0HMC90.0R0HMC9_9BRAS; Uncharacterized protein
STRINGXP_006292160.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63042743
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.20.0DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]