PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10009432m
Common NameCARUB_v10009432mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family E2F/DP
Protein Properties Length: 384aa    MW: 43664 Da    PI: 6.6856
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10009432mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.11.3e-27155220171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      r+++sL+llt+kf+kl++++e+g+++ln +a+ L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  Carubv10009432m 155 RYDSSLGLLTKKFVKLIQEAEDGTLDLNYCADVL---EV--QKRRIYDITNVLEGIGLIEKTTKNHIRWKG 220
                      6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.6E-29151222IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.0E-34155220IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.52E-18155218IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.5E-25157220IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.07E-40231337No hitNo description
SuperFamilySSF1440742.88E-29231336No hitNo description
PfamPF164211.6E-25236334IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 384 aa     Download sequence    Send to blast
MAATSNSGED PTLSYLHHHR SPFRFELLQS ISSSDPRYSS LNPSSTNRPF LVSESLPNTQ  60
QSPLIPSHWD DSYSHITHKV QKSIKNHRIQ LGSMANMSGE SIDIAKVIVK QETPQDVVKR  120
VYNKSKGTKQ SKAGKRMANG EAQNGGLIVA SNNCRYDSSL GLLTKKFVKL IQEAEDGTLD  180
LNYCADVLEV QKRRIYDITN VLEGIGLIEK TTKNHIRWKG ADNLGQKDLG DQINRLKSEV  240
ESMRFEESRL DDLIRERQEA LRSLEEDEYC RRYMFMTEED ITSLPRFQNQ TLLAIKAPTA  300
SYIEVPDPDE MHFPQRQYRM VIRSRMGPID VYLLSKYKGD SGETSDKLGH ESDQKAPSRL  360
KADYWFESDA EVSLTDLWSN FSS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A7e-25155221774PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10009432m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2425810.0AF242581.1 Arabidopsis thaliana E2F transcription factor-2 E2F2 mRNA, complete cds.
GenBankAJ4178340.0AJ417834.1 Arabidopsis thaliana mRNA for transcription factor E2Fc (e2Fc gene).
GenBankAY0456360.0AY045636.1 Arabidopsis thaliana At1g47870/T2E6_2 mRNA, complete cds.
GenBankAY0582310.0AY058231.1 Arabidopsis thaliana At1g47870/T2E6_2 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023645560.10.0transcription factor E2FC isoform X1
SwissprotQ9FV700.0E2FC_ARATH; Transcription factor E2FC
TrEMBLR0I6M60.0R0I6M6_9BRAS; Uncharacterized protein
STRINGXP_006305066.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.10.0E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]