PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10008817m
Common NameCARUB_v10008817mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family NAC
Protein Properties Length: 533aa    MW: 59667.6 Da    PI: 5.2311
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10008817mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM155.81.9e-48111361128
              NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkev 92 
                      l+pGfrFhPtdeelvv+yLk+k+++kkl++ e+i e+d+yk++P++Lp k  +k+++++w+fFs rd+k+  g+r++rat++gyWkatgkd+ +
  Carubv10008817m  11 LAPGFRFHPTDEELVVYYLKRKIRRKKLRV-EAIGETDVYKFDPEELPeKaLHKTRDRQWFFFSLRDRKH--GSRSSRATDRGYWKATGKDRVI 101
                      579***************************.89**************95335566888**********86..89******************** PP

              NAM  93 lskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                      ++ +++ vg kktLvf++grap+ge+t+Wvmhey++
  Carubv10008817m 102 KC-DSRPVGEKKTLVFHRGRAPNGERTNWVMHEYTM 136
                      **.999****************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.09E-547161IPR003441NAC domain
PROSITE profilePS5100552.74311161IPR003441NAC domain
PfamPF023653.2E-2613135IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010114Biological Processresponse to red light
GO:0010224Biological Processresponse to UV-B
GO:0031930Biological Processmitochondria-nucleus signaling pathway
GO:1900409Biological Processpositive regulation of cellular response to oxidative stress
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0016021Cellular Componentintegral component of membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 533 aa     Download sequence    Send to blast
MMDLTGENGG LAPGFRFHPT DEELVVYYLK RKIRRKKLRV EAIGETDVYK FDPEELPEKA  60
LHKTRDRQWF FFSLRDRKHG SRSSRATDRG YWKATGKDRV IKCDSRPVGE KKTLVFHRGR  120
APNGERTNWV MHEYTMHEEE LKRCGGGDVK DAYVLYKIYK KSGSGPKNGE QYGAPFIEEE  180
WVEEGDEVDE PVDVVHVPAN QVIVSDGVDS NLWSKGLNQS QLDDNDIEEL MRQVSDQPGP  240
TVQLNGVSGL DSHVESYNLV NLEKDMYLEI DDLLLPEPEP TSVEAMQKDW NQDSSGVLND  300
NDFVDADSYF CDLGARNLEP DPVSGHFENG FEQSLLMNTS LVTDQANNNQ FPQHTRKNQA  360
SNWPLRNSYT RKMNSGSSLM QEPNNDRLTA ARFVEVPGTG DPSKFTNPLP SGTSITKEDE  420
AAKDESSQFA SSLWAFLESV PANPAYASEN PFVKLNLVRM SNSGGLFRFA SKSNAVVMAS  480
DSAVNRKKSG GKTDKKNNKS KGFFCLSIIG ALCALFWVII GTMGLSGRSL LW*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A2e-431116720174NAC domain-containing protein 19
3swm_B2e-431116720174NAC domain-containing protein 19
3swm_C2e-431116720174NAC domain-containing protein 19
3swm_D2e-431116720174NAC domain-containing protein 19
3swp_A2e-431116720174NAC domain-containing protein 19
3swp_B2e-431116720174NAC domain-containing protein 19
3swp_C2e-431116720174NAC domain-containing protein 19
3swp_D2e-431116720174NAC domain-containing protein 19
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
13138KIRRKKLR
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction. Interacts directly with the mitochondrial dysfunction DNA consensus motif 5'-CTTGNNNNNCA[AC]G-3', a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance. {ECO:0000269|PubMed:24045019}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00176DAPTransfer from AT1G32870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10008817m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat, salt stress, abscisic acid (ABA) and methyl methanesulfonate (MMS) treatment. {ECO:0000269|PubMed:17158162}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006307217.10.0NAC domain-containing protein 13
SwissprotF4IED20.0NAC13_ARATH; NAC domain-containing protein 13
TrEMBLR0IN970.0R0IN97_9BRAS; Uncharacterized protein
STRINGXP_006307217.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM153171517
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32870.10.0NAC domain protein 13
Publications ? help Back to Top
  1. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  2. O'Shea C, et al.
    Structures and Short Linear Motif of Disordered Transcription Factor Regions Provide Clues to the Interactome of the Cellular Hub Protein Radical-induced Cell Death1.
    J. Biol. Chem., 2017. 292(2): p. 512-527
    [PMID:27881680]