PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_80_iso_10

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

HSF

Protein Properties

Length: 333aa MW: 37100.3 Da PI: 7.4562

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_80_iso_10	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	120.4	1e-37	11	102	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXT CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskske 76 Fl+k+y++++d+ ++++isw+eng++fvv+++ efak++Lp+yFkh+nf+SFvRQLn+YgF+k+ ++ cra_locus_80_iso_10_len_1487_ver_3 11 FLTKTYQLVDDPITDDVISWNENGTAFVVWKTAEFAKDLLPNYFKHNNFSSFVRQLNTYGFRKIVPDK------- 78 9**************************************************************999....... PP TSEEEEESXXXXXXXXXXXXXXXXXX CS HSF_DNA-bind 77 kiweFkhksFkkgkkellekikrkks 102 weF++++Fk+g+k+ll++i+r+k+ cra_locus_80_iso_10_len_1487_ver_3 79 --WEFANENFKRGQKHLLTEIRRRKT 102 ..********************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	8.4E-39	3	95	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	1.1E-61	7	100	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	2.99E-34	8	100	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	8.6E-21	11	34	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	7.9E-33	11	100	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	8.6E-21	49	61	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	50	74	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	8.6E-21	62	74	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009408	Biological Process	response to heat
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 333 aa Download sequence Send to blast
MSQQRTVPAP FLTKTYQLVD DPITDDVISW NENGTAFVVW KTAEFAKDLL PNYFKHNNFS 60 SFVRQLNTYG FRKIVPDKWE FANENFKRGQ KHLLTEIRRR KTSLLPSSKT TSCSKSKAPA 120 PAPTNSGEDL GSSSTSSPDS KNPGSVDTVP CSYSAAQFAD LSDENEKLRK DNHILSLELA 180 QTKKQCQELI SFLTKHVKVV PHDQINRIMT TTSSSHHEHG TTSVAHDQVQ PQLTTATLPP 240 SDHHHHNDDD DHMNGRDQES LRLFGVLLKS DKKKRGRPYN DDIDIDIGVG AGAGAHQTKE 300 IKTTMDFDAA PSSSWTKLTI SCYGQSSKVC ATE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	8e-27	1	104	11	124	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019229441.1	1e-119	PREDICTED: heat shock factor protein HSF24
Swissprot	P22335	1e-104	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A314KLD5	1e-117	A0A314KLD5_NICAT; Heat shock factor protein hsf24
STRING	EOX91407	1e-114	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA9991	21	27

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]