PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_56471_iso_2

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

bZIP

Protein Properties

Length: 195aa MW: 22086.5 Da PI: 8.8598

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_56471_iso_2	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	37.5	5.2e-12	16	73	4	61
XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklks 61 ++ +r+ +NRe+ArrsR +K+++++eL ++ ++++eNk+L ++ ++++ + + cra_locus_56471_iso_2_len_715_ver_3 16 ERKRKRMLSNRESARRSRMKKQQRLDELITEENQMKEENKKLGHMIDGATQLYLNFAT 73 567899************************************9999998888776655 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	1.7E-11	5	59	No hit	No description
SMART	SM00338	1.8E-16	13	77	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.185	15	57	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	1.5E-8	17	64	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	2.31E-10	17	69	No hit	No description
CDD	cd14702	2.55E-19	18	68	No hit	No description
PROSITE pattern	PS00036	0	20	35	IPR004827	Basic-leucine zipper domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 195 aa Download sequence Send to blast
MASKQRPTSP GSDNDERKRK RMLSNRESAR RSRMKKQQRL DELITEENQM KEENKKLGHM 60 IDGATQLYLN FATENNVLRA QMAELTDRLR SLNSVLQIAS EVSGLVFDIQ DIPDTFPEPW 120 QLPCPIQPIP ASVDAFQHXA MMARILIVGA LPWFPMVGLN MLLLLMVLKG KPAPRHAAYA 180 TPIDGISLFM LSCCY

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA to the C-box-like motif (5'-TGCTGACGTCA-3'), ABRE elements, G-box-like motif (5'-CCACGTGGCC-3'), DOF (5'-AAAG-3'), I-box (5'-GATAA-3'), BS1 (5'-AGCGGG-3'), MY3 (5'-CGACG-3'), 5'-CAGTGCGC-3' and 5'-ACTCAT-3' sequence in target gene promoters (PubMed:15047879, PubMed:16810321, PubMed:19531597, PubMed:21278122, PubMed:25108460). DNA-binding and subsequent transcription activation is triggered by heterodimerization with other bZIP proteins (e.g. BZIP1, BZIP10 and BZIP25) (PubMed:16810321, PubMed:19531597, PubMed:21278122). Promotes POX1/PRODH1 expression in response to hypoosmolarity stress (PubMed:15047879, PubMed:16810321). Transcriptional activator of seed maturation (MAT) genes (e.g. AT2S2), including seed storage protein (SSP) and late embryogenesis abundant (LEA) genes (PubMed:19531597). Activated by low energy stress both by transcriptional and post-transcriptional mechanisms. Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark-induced starvation response, especially when heterodimerized with BZIP1, by triggering accumulation of sepcific proteins including ASN1 and POX1/PRODH1 (PubMed:21278122). {ECO:0000269\|PubMed:15047879, ECO:0000269\|PubMed:16810321, ECO:0000269\|PubMed:19531597, ECO:0000269\|PubMed:21278122, ECO:0000269\|PubMed:25108460}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By hypoosmolarity (PubMed:15047879, PubMed:16810321). Accumulates during dark-induced starvation (PubMed:21278122). {ECO:0000269\|PubMed:15047879, ECO:0000269\|PubMed:16810321, ECO:0000269\|PubMed:21278122}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011079554.1	4e-77	bZIP transcription factor 53
Swissprot	Q9LZP8	3e-49	BZP53_ARATH; bZIP transcription factor 53
TrEMBL	A0A2G9G0L6	2e-74	A0A2G9G0L6_9LAMI; Uncharacterized protein
STRING	Migut.D00084.1.p	2e-74	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2810	23	51

Publications ? help Back to Top
Restovic F,Espinoza-Corral R,Gómez I,Vicente-Carbajosa J,Jordana X An active Mitochondrial Complex II Present in Mature Seeds Contains an Embryo-Specific Iron-Sulfur Subunit Regulated by ABA and bZIP53 and Is Involved in Germination and Seedling Establishment. Front Plant Sci, 2017. 8: p. 277 [PMID:28293251] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Jain P, et al. A-ZIP53, a dominant negative reveals the molecular mechanism of heterodimerization between bZIP53, bZIP10 and bZIP25 involved in Arabidopsis seed maturation. Sci Rep, 2017. 7(1): p. 14343 [PMID:29084982] Pedrotti L, et al. Snf1-RELATED KINASE1-Controlled C/S1-bZIP Signaling Activates Alternative Mitochondrial Metabolic Pathways to Ensure Plant Survival in Extended Darkness. Plant Cell, 2018. 30(2): p. 495-509 [PMID:29348240]