PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | cra_locus_4762_iso_1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
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Family | C2H2 | ||||||||
Protein Properties | Length: 369aa MW: 42583.3 Da PI: 6.6252 | ||||||||
Description | C2H2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | zf-C2H2 | 12.3 | 0.0005 | 78 | 100 | 3 | 23 |
ET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 3 Cp..dCgksFsrksnLkrHirtH 23 C+ Cgk+F + L++H H cra_locus_4762_iso_1_len_1665_ver_3 78 CSyeGCGKTFIDAGALRKHSHIH 100 77779**************7766 PP | |||||||
2 | zf-C2H2 | 15 | 6.9e-05 | 105 | 129 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 y C+ +Cgk F ++s LkrH H cra_locus_4762_iso_1_len_1665_ver_3 105 YICHyeNCGKKFLDSSKLKRHFLIH 129 89*******************8877 PP | |||||||
3 | zf-C2H2 | 21.7 | 5.3e-07 | 135 | 159 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 ++Cp Cgk Fs nL++H++tH cra_locus_4762_iso_1_len_1665_ver_3 135 FVCPheGCGKAFSLDFNLRSHMKTH 159 89**********************9 PP | |||||||
4 | zf-C2H2 | 17.6 | 1e-05 | 165 | 189 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 + Cp dCgk++ + + Lk+Hi++H cra_locus_4762_iso_1_len_1665_ver_3 165 HICPyaDCGKRYAHEYKLKNHISSH 189 68**********************6 PP | |||||||
5 | zf-C2H2 | 16.1 | 3.3e-05 | 227 | 252 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y+Cp C+k + + + L+ H+r+ H cra_locus_4762_iso_1_len_1665_ver_3 227 YTCPyeGCDKAYIHEYKLNLHLRReH 252 9**********************999 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:3.30.160.60 | 9.1E-14 | 71 | 102 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
PROSITE profile | PS50157 | 10.783 | 76 | 105 | IPR007087 | Zinc finger, C2H2 |
SMART | SM00355 | 0.0032 | 76 | 100 | IPR015880 | Zinc finger, C2H2-like |
PROSITE pattern | PS00028 | 0 | 78 | 100 | IPR007087 | Zinc finger, C2H2 |
SuperFamily | SSF57667 | 4.54E-8 | 79 | 129 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 7.8E-14 | 103 | 125 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 0.013 | 105 | 129 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 14.066 | 105 | 134 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 107 | 129 | IPR007087 | Zinc finger, C2H2 |
SuperFamily | SSF57667 | 1.39E-14 | 116 | 169 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 3.5E-20 | 126 | 159 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 3.1E-4 | 135 | 159 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 12.695 | 135 | 164 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 137 | 159 | IPR007087 | Zinc finger, C2H2 |
Gene3D | G3DSA:3.30.160.60 | 2.9E-8 | 160 | 191 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
PROSITE profile | PS50157 | 9.245 | 165 | 194 | IPR007087 | Zinc finger, C2H2 |
SMART | SM00355 | 0.0069 | 165 | 189 | IPR015880 | Zinc finger, C2H2-like |
PROSITE pattern | PS00028 | 0 | 167 | 190 | IPR007087 | Zinc finger, C2H2 |
SuperFamily | SSF57667 | 9.66E-6 | 221 | 250 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 9.4E-9 | 221 | 250 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
PROSITE profile | PS50157 | 10.097 | 227 | 257 | IPR007087 | Zinc finger, C2H2 |
SMART | SM00355 | 0.0019 | 227 | 252 | IPR015880 | Zinc finger, C2H2-like |
PROSITE pattern | PS00028 | 0 | 229 | 252 | IPR007087 | Zinc finger, C2H2 |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0045892 | Biological Process | negative regulation of transcription, DNA-templated | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0043565 | Molecular Function | sequence-specific DNA binding | ||||
GO:0046872 | Molecular Function | metal ion binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 369 aa Download sequence Send to blast |
METHMNHNLF ERRSITKSRA PAVKWFKEWV PQDVVATGGK CQLLRWVNEA TLKALREKKE 60 PELPEPEPEP TTEVLFLCSY EGCGKTFIDA GALRKHSHIH GERQYICHYE NCGKKFLDSS 120 KLKRHFLIHT GERDFVCPHE GCGKAFSLDF NLRSHMKTHS QENYHICPYA DCGKRYAHEY 180 KLKNHISSHH EKNVVEPTKY VPPAEKPVKT PKSSNATYAS ASSDRPYTCP YEGCDKAYIH 240 EYKLNLHLRR EHPGHSKEEN AKNVQFTADN DMDEASDHDP YPAKRSNDKK PSRSKPNLKL 300 PPAKVAQRKG STASQANMSV MKKQWPVKEE VYDEEDSEET EEERDNVGDG WRYAGNDDDD 360 DDEETEYED |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1ubd_C | 3e-35 | 78 | 248 | 4 | 117 | PROTEIN (YY1 ZINC FINGER DOMAIN) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_022897013.1 | 0.0 | zinc finger transcription factor YY1 | ||||
Swissprot | Q2V3L3 | 1e-148 | YY1_ARATH; Zinc finger transcription factor YY1 | ||||
TrEMBL | A0A068TML9 | 0.0 | A0A068TML9_COFCA; Uncharacterized protein | ||||
STRING | PGSC0003DMT400023459 | 0.0 | (Solanum tuberosum) |
Publications ? help Back to Top | |||
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