PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_4594_iso_2
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family bHLH
Protein Properties Length: 585aa    MW: 64868 Da    PI: 6.8458
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_4594_iso_2genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.69.6e-13419465455
                                          HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                                  HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                                          +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  cra_locus_4594_iso_2_len_2637_ver_3 419 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITELQ 465
                                          799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142159.4E-5534222IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.85415464IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.96E-14418469No hitNo description
SuperFamilySSF474593.14E-18418478IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.3E-10419465IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.2E-18419478IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.2E-16421470IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 585 aa     Download sequence    Send to blast
MVAAVLGTKA FDFLFSNTVS ADGSLMVMGN DENLQNKLSD LVEHPNAANF SWNYAIFWQI  60
SRSKSGELVL GWGDGCCREP RDGEESEFTQ ILSLRLEDET QQRMRKRVLQ KLHTCFGGTE  120
EDSYAFGLDR VTDTEMFFLA SMYFSFPRGE GGPGKCFGSG KPFWLSDSLK SSTDYCVRSF  180
LAKSAGMRTI VLIPTDVGVV ELGSVRCIPE SFEVMQSVRS SFSLYSSLIR AKQVAPVTVA  240
ADVDGNAAYM NLGIGQRPDS VHKIFGQDLN SIHAQSREKL VVRKPDERKW DAYPNGNRIT  300
TFPNTCNGLN NTAWPQFNHV KPGNPVELYS PQTQPNNLQG FVNGASRVNN FQHQKPAQMQ  360
IDFTGATSRP VVSRPVSAES EHSDIEASCR EESAVLAADE KRPRKRGRKP ANGREEPLNH  420
VEAERQRREK LNQRFYALRA VVPNISKMDK ASLLGDAIAY ITELQKKLRD LESEKEKVGS  480
TSRDALAFEK NASSGVENQV PEIDIEAARD EVIVKVTCPL DAHPVSGVIQ AFKETQVNVL  540
DSKLATGNET VFHTFVVKSQ GSDKLTKEKL IAAMSRDREA TSQSS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-29413475264Transcription factor MYC2
5gnj_B2e-29413475264Transcription factor MYC2
5gnj_E2e-29413475264Transcription factor MYC2
5gnj_F2e-29413475264Transcription factor MYC2
5gnj_G2e-29413475264Transcription factor MYC2
5gnj_I2e-29413475264Transcription factor MYC2
5gnj_M2e-29413475264Transcription factor MYC2
5gnj_N2e-29413475264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1400408KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027160117.10.0transcription factor bHLH13 isoform X1
RefseqXP_027160118.10.0transcription factor bHLH13 isoform X2
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A2U9IXW70.0A0A2U9IXW7_CATRO; Jasmonate-associated MYC2-like 2
STRINGXP_009781532.10.0(Nicotiana sylvestris)
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]