PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_4255_iso_2

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

bZIP

Protein Properties

Length: 298aa MW: 32594.6 Da PI: 6.633

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_4255_iso_2	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	28.1	4.5e-09	88	135	4	51
XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkelee 51 k +r N+eA r++R++Kka+ + Le++v +L a N++L k+l+ cra_locus_4255_iso_2_len_2870_ver_3 88 KKSKKRPLGNKEAVRKYREKKKARAASLEDEVVKLRALNQQLMKRLQG 135 577889999**********************************99975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	1.2E-13	81	153	No hit	No description
SMART	SM00338	3.3E-10	85	152	IPR004827	Basic-leucine zipper domain
Pfam	PF07716	3.6E-12	86	135	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	8.99	87	134	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	1.81E-6	89	134	No hit	No description
CDD	cd14686	8.53E-12	91	144	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0071294	Biological Process	cellular response to zinc ion
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 298 aa Download sequence Send to blast
MDDGELEFSN HEIFSGSSFG DLPSSCSMGN FLDEILKDTH ACTHTHTCNP PGPDNSHTHT 60 CYHVHTKIVP APSEDKTPTD DTAESTEKKS KKRPLGNKEA VRKYREKKKA RAASLEDEVV 120 KLRALNQQLM KRLQGQAVLE AEIARLKCLL VDIRGRIEGE IGSFPYQRPS NKTGDVYQNL 180 VNPNSSGGVC GNPCNLQCND QLYCLHPGVD GKNVDNGPLS DQGYNDCEFE NIQCLGSQNP 240 GLKELPGCGM GSKIPSLSPN TANGGQHKGV THAGNAVIFL FYTQFFILPK SETLHLIN

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the response to zinc ion deficiency. Binds to the consensus sequence 5'-[AG]TGTCGACA[CT]-3' also called zinc deficiency response element (ZDRE). The ZDRE sequence is conserved in the plant kingdom and present in the promoters of genes that constitute the primary response to zinc deficiency, comprising additional ZIP metal transporter genes (PubMed:20479230, PubMed:26306426). Required for zinc accumulation in roots. Mediates the expression of the zinc transporter ZIP12 during growth in zinc-deficient conditions. ZIP12 transporter is involved in zinc uptake in roots (PubMed:26306426). {ECO:0000269\|PubMed:20479230, ECO:0000269\|PubMed:26306426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by zinc deficiency. {ECO:0000269\|PubMed:20479230}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027089253.1	1e-164	basic leucine zipper 23-like
Refseq	XP_027089254.1	1e-164	basic leucine zipper 23-like
Refseq	XP_027184698.1	1e-164	basic leucine zipper 23-like isoform X2
Swissprot	Q8GTS2	1e-100	BZP23_ARATH; Basic leucine zipper 23
TrEMBL	A0A068V3V1	1e-161	A0A068V3V1_COFCA; Uncharacterized protein
STRING	XP_009797256.1	1e-142	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2989	24	52

Publications ? help Back to Top
Azevedo H, et al. Transcriptomic profiling of Arabidopsis gene expression in response to varying micronutrient zinc supply. Genom Data, 2016. 7: p. 256-8 [PMID:26981422] Castro PH, et al. Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants. Sci Rep, 2017. 7(1): p. 3806 [PMID:28630437] Nazri AZ,Griffin JHC,Peaston KA,Alexander-Webber DGA,Williams LE F-group bZIPs in barley-a role in Zn deficiency. Plant Cell Environ., 2017. 40(11): p. 2754-2770 [PMID:28763829] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]