PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | cra_locus_39137_iso_1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
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Family | bHLH | ||||||||
Protein Properties | Length: 353aa MW: 39035.7 Da PI: 6.0198 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 38.4 | 2.3e-12 | 145 | 196 | 1 | 55 |
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +r++h ++Er+RR+++N+ + Lr+l+P + + ++ + a+i A+e++++L+ cra_locus_39137_iso_1_len_1392_ver_3 145 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 196 79****************************...9*****************9995 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
CDD | cd00083 | 3.30E-13 | 143 | 200 | No hit | No description |
Gene3D | G3DSA:4.10.280.10 | 1.1E-13 | 143 | 199 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
PROSITE profile | PS50888 | 15.428 | 144 | 195 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SuperFamily | SSF47459 | 1.96E-16 | 144 | 208 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 1.0E-9 | 145 | 196 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 3.4E-9 | 150 | 201 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd04873 | 0.00303 | 279 | 343 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0010377 | Biological Process | guard cell fate commitment | ||||
GO:0045597 | Biological Process | positive regulation of cell differentiation | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 353 aa Download sequence Send to blast |
MEKEGNNYSP SNFTSSSVLD HHHYMMMKPQ IGSGEISTSS SVAAAAAAAD QENGIIDPVY 60 FLKFPVLNDK LQDENDQENH HQWGSEESKE ENNNGLVQLG FLGENIAVED DIKKKKVGGV 120 GENNNNKNKR KRARSVKTSE EVESQRMTHI AVERNRRKQM NEHLRVLRSL MPGSYVQRGD 180 QASIIGGAIE FVRELEQLLQ CLESQKRRRL YGDGGGGGSR QIAAAGDTSS SPLAIQQPPT 240 FMPPLPNELE TGGGLHEETA ESKSCLADIE VKVFGFDAMI KILSRRRPGQ LIKTIAALED 300 LQLNILHTNI TTIEQTVLYS FNVKVGGEAR YTAEDIANSV QQIFSFIHAN TTI |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 113 | 131 | KKKVGGVGENNNNKNKRKR |
2 | 145 | 156 | RMTHIAVERNRR |
3 | 205 | 209 | KRRRL |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_027165028.1 | 1e-139 | transcription factor FAMA isoform X2 | ||||
Swissprot | Q56YJ8 | 1e-130 | FAMA_ARATH; Transcription factor FAMA | ||||
TrEMBL | A0A068TT28 | 1e-137 | A0A068TT28_COFCA; Uncharacterized protein | ||||
STRING | XP_009795997.1 | 1e-135 | (Nicotiana sylvestris) |