PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | cra_locus_3682_iso_2 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
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Family | MYB | ||||||||
Protein Properties | Length: 350aa MW: 40901.9 Da PI: 10.1349 | ||||||||
Description | MYB family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | Myb_DNA-binding | 42.6 | 1.4e-13 | 4 | 53 | 1 | 48 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT..TTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg..kgRtlkqcksrwqkyl 48 r+rW +eEd ll + +q+G++ W++++++m+ ++R +k c +rw +yl cra_locus_3682_iso_2_len_1901_ver_3 4 RQRWQAEEDALLRAYARQYGPREWHLVSERMNkpLNRDPKACLERWKNYL 53 89**********************************************97 PP | |||||||
2 | Myb_DNA-binding | 35.2 | 2.9e-11 | 59 | 103 | 1 | 47 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +g+ T+eE+ l +++ +++G++ Wk+Ia++++ gRt+k + +w + cra_locus_3682_iso_2_len_1901_ver_3 59 KGSLTEEEQRLVIHLQTKYGNK-WKRIAAEIP-GRTAKRLGKWWEVF 103 6788******************.*********.*****999999766 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
PROSITE profile | PS51294 | 22.68 | 1 | 57 | IPR017930 | Myb domain |
SMART | SM00717 | 7.5E-12 | 3 | 55 | IPR001005 | SANT/Myb domain |
SuperFamily | SSF46689 | 4.12E-20 | 4 | 98 | IPR009057 | Homeodomain-like |
CDD | cd00167 | 6.54E-7 | 6 | 53 | No hit | No description |
Gene3D | G3DSA:1.10.10.60 | 1.1E-18 | 6 | 60 | IPR009057 | Homeodomain-like |
Pfam | PF13921 | 6.6E-14 | 7 | 68 | No hit | No description |
PROSITE profile | PS51294 | 17.91 | 58 | 108 | IPR017930 | Myb domain |
SMART | SM00717 | 6.9E-9 | 58 | 106 | IPR001005 | SANT/Myb domain |
Gene3D | G3DSA:1.10.10.60 | 2.0E-14 | 61 | 102 | IPR009057 | Homeodomain-like |
CDD | cd00167 | 6.21E-6 | 63 | 104 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008356 | Biological Process | asymmetric cell division | ||||
GO:0009615 | Biological Process | response to virus | ||||
GO:0009651 | Biological Process | response to salt stress | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0009739 | Biological Process | response to gibberellin | ||||
GO:0009751 | Biological Process | response to salicylic acid | ||||
GO:0009753 | Biological Process | response to jasmonic acid | ||||
GO:0009944 | Biological Process | polarity specification of adaxial/abaxial axis | ||||
GO:0010338 | Biological Process | leaf formation | ||||
GO:0042742 | Biological Process | defense response to bacterium | ||||
GO:0045088 | Biological Process | regulation of innate immune response | ||||
GO:0045892 | Biological Process | negative regulation of transcription, DNA-templated | ||||
GO:0046686 | Biological Process | response to cadmium ion | ||||
GO:0050832 | Biological Process | defense response to fungus | ||||
GO:0000793 | Cellular Component | condensed chromosome | ||||
GO:0005730 | Cellular Component | nucleolus | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0042803 | Molecular Function | protein homodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 350 aa Download sequence Send to blast |
MKERQRWQAE EDALLRAYAR QYGPREWHLV SERMNKPLNR DPKACLERWK NYLKPGIKKG 60 SLTEEEQRLV IHLQTKYGNK WKRIAAEIPG RTAKRLGKWW EVFKEKQQRE QKENRRIIEP 120 TTELGKYNHI LETFAEKLVK QQQNFQGFLM ATPNGAFIRP DTTAPSQPTL LPPWLSNSPA 180 TSTVRAPSPS VTLSLSPSVV QSSPAAIPWM QPDRSSLPSR GINIPSRENP FIPELLECCK 240 ELEEKHGAWV AHKKEAAWRL RRVELQLESE KACKKREKME EIEAKVKALR EEQKATLERI 300 EAEYREQLAE LRRDADVKEQ KLADQWAAKH SRLVKFLEQM GFQPRMDEPN |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1gv2_A | 2e-14 | 7 | 92 | 7 | 89 | MYB PROTO-ONCOGENE PROTEIN |
1mse_C | 2e-14 | 7 | 92 | 7 | 89 | C-Myb DNA-Binding Domain |
1msf_C | 2e-14 | 7 | 92 | 7 | 89 | C-Myb DNA-Binding Domain |
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Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription factor required for normal cell differentiation. Positively regulates LATERAL ORGAN BOUNDARIES (LOB) within the shoot apex, and the class III HD-ZIP genes REV, PHB, and PHV. Interacts directly with ASYMMETRIC LEAVES 2 (LBD6/AS2) to repress the knox homeobox genes BP/KNAT1, KNAT2, and KNAT6 and the abaxial determinants ARF3/ETT, KAN2 and YAB5. May act in parallel with the RDR6-SGS3-AGO7 pathway, an endogenous RNA silencing pathway, to regulate the leaf morphogenesis (PubMed:11076771, PubMed:11140682, PubMed:11882937, PubMed:12750468, PubMed:16006579, PubMed:16699177, PubMed:17395603, PubMed:17559509, PubMed:23271976). Binds directly to KNAT1, KNAT2, and KNATM chromatin, regulating leaf development (PubMed:23271976). LBD6 is required for this binding (PubMed:23271976). Positive regulator of flowering that binds to the promoter of FT (PubMed:21950734). Regulates FT expression by forming a functional complex with CO (PubMed:21950734). Involved in leaf polarity establishment by functioning cooperatively with NUCL1 to repress abaxial genes ARF3, ARF4, KAN1, KAN2, YAB1 and YAB5, and the knox homeobox genes KNAT1, KNAT2, KNAT6, and STM to promote adaxial development in leaf primordia at shoot apical meristems at high temperatures (PubMed:27334696). {ECO:0000269|PubMed:11076771, ECO:0000269|PubMed:11140682, ECO:0000269|PubMed:11882937, ECO:0000269|PubMed:12750468, ECO:0000269|PubMed:16006579, ECO:0000269|PubMed:16699177, ECO:0000269|PubMed:17395603, ECO:0000269|PubMed:17559509, ECO:0000269|PubMed:23271976, ECO:0000269|PubMed:27334696}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Circadian-regulation with an afternoon peak in long days and with a broad night peak in short days (PubMed:21950734). Expression of AS1 in stem cells of the shoot apical meristem is prevented by SHOOT MERISTEMLESS (STM). Expression is activated by GTE6 during leaf morphogenesis (PubMed:16166385). {ECO:0000269|PubMed:16166385, ECO:0000269|PubMed:21950734}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_009602924.1 | 0.0 | PREDICTED: transcription factor AS1 | ||||
Refseq | XP_009602925.1 | 0.0 | PREDICTED: transcription factor AS1 | ||||
Refseq | XP_018626922.1 | 0.0 | PREDICTED: transcription factor AS1 | ||||
Swissprot | O80931 | 1e-150 | AS1_ARATH; Transcription factor AS1 | ||||
TrEMBL | V9LXP3 | 0.0 | V9LXP3_TOBAC; Asymmetric leaves 1 | ||||
STRING | XP_009602924.1 | 0.0 | (Nicotiana tomentosiformis) |