PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_25027_iso_1

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

bHLH

Protein Properties

Length: 108aa MW: 12594.3 Da PI: 4.6146

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_25027_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	28	3.8e-09	45	84	10	54
HHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 10 rrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L cra_locus_25027_iso_1_len_415_ver_3 45 RHRRERISEKIRILQRLVPGG-----TKMDTASMLDEAIRYVKFL 84 89***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	13.351	35	84	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.9E-12	41	90	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	8.99E-9	44	89	No hit	No description
SuperFamily	SSF47459	3.01E-14	44	93	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.7E-13	45	94	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.4E-6	45	84	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 108 aa Download sequence Send to blast
MEEEEEDQHH DEEEEAEEEL GTMKEMMFKI AAMQPVDIDP XXXARHRRER ISEKIRILQR 60 LVPGGTKMDT ASMLDEAIRY VKFLKRQIRE LQANQPPSLA VNSTCPPX

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription regulator required for seed dispersal. Involved in the differentiation of all three cell types required for fruit dehiscence. Acts as the key regulator in a network including SHP and ALC that controls specification of the valve margin. Works with ALC, SHP, and FUL to allow differentiation of the lignified valve layer, the spring-loaded mechanism of fruit that promotes opening. Regulates the expression of the YJ80 marker. {ECO:0000269\|PubMed:15035986}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By FUL, which restrict its expression to the margins.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027077794.1	4e-46	transcription factor HEC3-like
Swissprot	O81313	2e-28	IND_ARATH; Transcription factor IND
TrEMBL	A0A2Z7AI31	8e-38	A0A2Z7AI31_9LAMI; Uncharacterized protein
STRING	cassava4.1_031791m	1e-37	(Manihot esculenta)
STRING	GRMZM2G354618_P01	1e-37	(Zea mays)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA752	23	101

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Pabón-Mora N,Wong GK,Ambrose BA Evolution of fruit development genes in flowering plants. Front Plant Sci, 2014. 5: p. 300 [PMID:25018763] Moubayidin L,Ostergaard L Dynamic control of auxin distribution imposes a bilateral-to-radial symmetry switch during gynoecium development. Curr. Biol., 2014. 24(22): p. 2743-8 [PMID:25455035] Jaradat MR,Ruegger M,Bowling A,Butler H,Cutler AJ A comprehensive transcriptome analysis of silique development and dehiscence in Arabidopsis and Brassica integrating genotypic, interspecies and developmental comparisons. GM Crops Food, 2014. 5(4): p. 302-20 [PMID:25523176] van Gelderen K,van Rongen M,Liu A,Otten A,Offringa R An INDEHISCENT-Controlled Auxin Response Specifies the Separation Layer in Early Arabidopsis Fruit. Mol Plant, 2016. 9(6): p. 857-69 [PMID:26995296] Balanzà V,Roig-Villanova I,Di Marzo M,Masiero S,Colombo L Seed abscission and fruit dehiscence required for seed dispersal rely on similar genetic networks. Development, 2016. 143(18): p. 3372-81 [PMID:27510967] Pfannebecker KC,Lange M,Rupp O,Becker A Seed Plant-Specific Gene Lineages Involved in Carpel Development. Mol. Biol. Evol., 2017. 34(4): p. 925-942 [PMID:28087776] He H, et al. CELLULASE6 and MANNANASE7 Affect Cell Differentiation and Silique Dehiscence. Plant Physiol., 2018. 176(3): p. 2186-2201 [PMID:29348141] Simonini S,Stephenson P,Østergaard L A molecular framework controlling style morphology in Brassicaceae. Development, 2018. [PMID:29440299] Li XR,Deb J,Kumar SV,Østergaard L Temperature Modulates Tissue-Specification Program to Control Fruit Dehiscence in Brassicaceae. Mol Plant, 2018. 11(4): p. 598-606 [PMID:29449088]