PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_12955_iso_3

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

bHLH

Protein Properties

Length: 586aa MW: 65513.3 Da PI: 6.2227

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_12955_iso_3	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	57.7	2.1e-18	262	311	2	55
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r +h++ E+rRR++iN++f++Lre++P++ ++K +Ka+ L +++eYI+ Lq cra_locus_12955_iso_3_len_2516_ver_3 262 RSKHSATEQRRRSKINDRFQKLREIIPHS----DQKRDKASFLLEVIEYIQFLQ 311 889***********************9....9*****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	3.2E-22	260	319	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.02E-17	260	320	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	16.907	260	310	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.3E-16	262	311	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.87E-15	262	315	No hit	No description
SMART	SM00353	2.1E-13	266	316	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:0009742	Biological Process	brassinosteroid mediated signaling pathway
GO:1902448	Biological Process	positive regulation of shade avoidance
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 586 aa Download sequence Send to blast
MELPQPRPFG TEGRKTTHDF LSLYSPAQQD PRPQGGFLKT HDFLQPLQQV GKDVTKEEDK 60 IEIKDVERPP PAAPPPPAVE HILPGGIGTY SITYFNQRIT KPEGNLFMMA QASSTNRTDE 120 NNSNSSSYTG SGFTLWDESA VKKGKTGKEN NVVDRPVPRE SVVNMGGGPW TTSSERPSQS 180 SSNQKNNNTT FSSPSTSQPS PATRNQSFMN MITSAKTLQE EDDDEEEEEE FIVKKEPTSH 240 PKGNLSVKLD VKSNDQKPCT PRSKHSATEQ RRRSKINDRF QKLREIIPHS DQKRDKASFL 300 LEVIEYIQFL QDKVHKFEGY PGWNQEPSKL MPWRNPRTPE DFINQTQPTN ISSGPASSML 360 AAKFEESKTG ASPVLPINGQ HLVESDISTA FREKVQQPEI TNKATSLPLP LRTSIFPFGG 420 VSNTSFPTSS RPPSDTEKPT SQAPQSPFWP SPGAFTSDNA VPDKVKDREI TIESGTINIS 480 SSTPKGELTS KDNDDKFCFH ELTSLELYEM VNLFVISNSL PTAEQVIEFS DTXXXXXXXX 540 XXXXXXXXXG YRXSNKQSSD AKICCNKHRR GFWASNEEAE NKQKLV

Sequence ? help Back to Top

Protein Sequence Length: 586 aa Download sequence Send to blast

MELPQPRPFG TEGRKTTHDF LSLYSPAQQD PRPQGGFLKT HDFLQPLQQV GKDVTKEEDK  60
IEIKDVERPP PAAPPPPAVE HILPGGIGTY SITYFNQRIT KPEGNLFMMA QASSTNRTDE  120
NNSNSSSYTG SGFTLWDESA VKKGKTGKEN NVVDRPVPRE SVVNMGGGPW TTSSERPSQS  180
SSNQKNNNTT FSSPSTSQPS PATRNQSFMN MITSAKTLQE EDDDEEEEEE FIVKKEPTSH  240
PKGNLSVKLD VKSNDQKPCT PRSKHSATEQ RRRSKINDRF QKLREIIPHS DQKRDKASFL  300
LEVIEYIQFL QDKVHKFEGY PGWNQEPSKL MPWRNPRTPE DFINQTQPTN ISSGPASSML  360
AAKFEESKTG ASPVLPINGQ HLVESDISTA FREKVQQPEI TNKATSLPLP LRTSIFPFGG  420
VSNTSFPTSS RPPSDTEKPT SQAPQSPFWP SPGAFTSDNA VPDKVKDREI TIESGTINIS  480
SSTPKGELTS KDNDDKFCFH ELTSLELYEM VNLFVISNSL PTAEQVIEFS DTXXXXXXXX  540
XXXXXXXXXG YRXSNKQSSD AKICCNKHRR GFWASNEEAE NKQKLV

Functional Description ? help Back to Top
Source	Description
UniProt	Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269\|PubMed:15680330}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00498	DAP	Transfer from AT5G08130	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by cold treatment. {ECO:0000269\|PubMed:12679534}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027123148.1	0.0	transcription factor BIM1-like isoform X1
Refseq	XP_027123149.1	0.0	transcription factor BIM1-like isoform X1
Swissprot	Q9LEZ3	1e-85	BIM1_ARATH; Transcription factor BIM1
TrEMBL	A0A068TT57	0.0	A0A068TT57_COFCA; Uncharacterized protein
STRING	Solyc03g114720.2.1	1e-169	(Solanum lycopersicum)

Publications ? help Back to Top
Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]