PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_11604_iso_5
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family TCP
Protein Properties Length: 637aa    MW: 70697.4 Da    PI: 6.7212
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_11604_iso_5genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP125.36.4e-392343722133
                                   TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt..ssssa.. 70 
                                           +g+kdrhsk++T++g+RdRRvRlsa++a++f+d+qd+LG+d++sk+++WL+++ak+ai+el+++     ++  
  cra_locus_11604_iso_5_len_2556_ver_3 234 TGRKDRHSKVCTAKGPRDRRVRLSAHTAIQFYDVQDRLGYDRPSKAVDWLIKKAKAAIDELAELpaW--TPta 304
                                           79**************************************************************652..4422 PP

                                   TCP  71 .....seceaesssssasnsssgkaaksaakskksqksaasalnlakesrakarararertrekmrik 133
                                                s++e+e+ ++++++++++++++++++++ + +++  + ++++ s++k  ++   +++e++++ 
  cra_locus_11604_iso_5_len_2556_ver_3 305 gtlvnSNFEQEQAQKQDAQNQQNAHQSQQQQQQLNVQHTDLMGSVSAGSSSKRAMTMLRNENEQQSMH 372
                                           43432444555555555555555666666667777777777777777555555555444444433333 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036346.7E-34234351IPR005333Transcription factor, TCP
PROSITE profilePS5136934.295236294IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009793Biological Processembryo development ending in seed dormancy
GO:0009965Biological Processleaf morphogenesis
GO:0030154Biological Processcell differentiation
GO:0045962Biological Processpositive regulation of development, heterochronic
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 637 aa     Download sequence    Send to blast
MELGRLNGRA FWERQISELW QKEHNKKEEE SSSEETRTSA AAEEEAPLRR KSLLPNQKLE  60
EQEKHSLKGL SLDPHRHQHH RFPNQIPFSR NVEEEQALEE EEEQEQQTGI FAAAPHHQHR  120
PQPHQSQELF QQLYARLETS AAEAAGGVGV PPLPQQPQPP KKRSYFPSSS TNPQNQESEH  180
ARLGEKMGES FHHQHQLQQQ PQQQLRQSSS SRLGLRHTGG EIVEVQGGHI VRSTGRKDRH  240
SKVCTAKGPR DRRVRLSAHT AIQFYDVQDR LGYDRPSKAV DWLIKKAKAA IDELAELPAW  300
TPTAGTLVNS NFEQEQAQKQ DAQNQQNAHQ SQQQQQQLNV QHTDLMGSVS AGSSSKRAMT  360
MLRNENEQQS MHHNSGNSSS SFLPPSLDSD SIADTIKSFF PMGASAEASS AMQFQSFPPP  420
DLLSRTSSQN QDLRLSLQSF QDPILLHHHQ GQQAQHHTTN NHTEQAQAQV QAHALFAGAT  480
QMGFDASSWG EHQQQSAEIG RFQRLASSWH AAGGDGQPSG GAVTGGYLFN SQPAPQPLLQ  540
QLFGQNQFFS QRGPLQSSNT PSVRAWMDPS AITIASADHI QNQHHAAVLP IYPSGIGFAS  600
GVGGFPGFHV PARIQGEEEE HDGLSDKPSS ASSDSRH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5zkt_A7e-20241294154Putative transcription factor PCF6
5zkt_B7e-20241294154Putative transcription factor PCF6
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164) (PubMed:12931144, PubMed:17307931). Required during early steps of embryogenesis (PubMed:15634699). Participates in ovule develpment (PubMed:25378179). Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter (PubMed:18816164). {ECO:0000269|PubMed:12931144, ECO:0000269|PubMed:15634699, ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:18816164, ECO:0000269|PubMed:25378179}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00009PBMTransfer from 929286Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the miRNA miR-JAW/miR319 (PubMed:12931144, PubMed:18816164). {ECO:0000269|PubMed:12931144, ECO:0000269|PubMed:18816164}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011082737.10.0transcription factor TCP4-like
RefseqXP_011082738.10.0transcription factor TCP4-like
SwissprotQ8LPR51e-101TCP4_ARATH; Transcription factor TCP4
TrEMBLA0A1S4A7101e-178A0A1S4A710_TOBAC; transcription factor TCP4-like
TrEMBLA0A1U7WZ071e-178A0A1U7WZ07_NICSY; transcription factor TCP4
STRINGXP_009785152.11e-179(Nicotiana sylvestris)
Publications ? help Back to Top
  1. Schommer C, et al.
    Control of jasmonate biosynthesis and senescence by miR319 targets.
    PLoS Biol., 2008. 6(9): p. e230
    [PMID:18816164]
  2. Ju Y, et al.
    Arabidopsis JINGUBANG Is a Negative Regulator of Pollen Germination That Prevents Pollination in Moist Environments.
    Plant Cell, 2016. 28(9): p. 2131-2146
    [PMID:27468890]
  3. Challa KR,Aggarwal P,Nath U
    Activation of YUCCA5 by the Transcription Factor TCP4 Integrates Developmental and Environmental Signals to Promote Hypocotyl Elongation in Arabidopsis.
    Plant Cell, 2016. 28(9): p. 2117-2130
    [PMID:27597774]
  4. Alvarez JP,Furumizu C,Efroni I,Eshed Y,Bowman JL
    Active suppression of a leaf meristem orchestrates determinate leaf growth.
    Elife, 2017.
    [PMID:27710768]
  5. Li J, et al.
    RABBIT EARS regulates the transcription of TCP4 during petal development in Arabidopsis.
    J. Exp. Bot., 2016. 67(22): p. 6473-6480
    [PMID:27838638]
  6. Sun X, et al.
    Activation of secondary cell wall biosynthesis by miR319-targeted TCP4 transcription factor.
    Plant Biotechnol. J., 2017. 15(10): p. 1284-1294
    [PMID:28233945]
  7. Kubota A, et al.
    TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis.
    PLoS Genet., 2017. 13(6): p. e1006856
    [PMID:28628608]
  8. Koyama T,Sato F,Ohme-Takagi M
    Roles of miR319 and TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2017. 175(2): p. 874-885
    [PMID:28842549]
  9. Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C
    Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2018. 176(2): p. 1694-1708
    [PMID:29133375]
  10. Vadde BVL,Challa KR,Nath U
    The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana.
    Plant J., 2018. 93(2): p. 259-269
    [PMID:29165850]
  11. Challa KR,Rath M,Nath U
    The CIN-TCP transcription factors promote commitment to differentiation in Arabidopsis leaf pavement cells via both auxin-dependent and independent pathways.
    PLoS Genet., 2019. 15(2): p. e1007988
    [PMID:30742619]