PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

evm.model.supercontig_87.103

Organism

Carica papaya

Taxonomic ID

3649

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

WRKY

Protein Properties

Length: 619aa MW: 66787.7 Da PI: 5.9166

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_87.103	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	97.3	1e-30	351	409	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+aed +++++tYeg+Hnh+ evm.model.supercontig_87.103 351 SDGCQWRKYGQKMAKGNPCPRAYYRCTMAaGCPVRKQVQRCAEDRTILITTYEGNHNHP 409 7*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.1E-33	335	411	IPR003657	WRKY domain
SuperFamily	SSF118290	8.89E-28	343	411	IPR003657	WRKY domain
PROSITE profile	PS50811	29.953	345	411	IPR003657	WRKY domain
SMART	SM00774	8.3E-37	350	410	IPR003657	WRKY domain
Pfam	PF03106	9.2E-27	352	409	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 619 aa Download sequence Send to blast
MAKGSGLSFD SDPSRFFLLK PTVLNSFPED NHDWKLINSH MDMDATPTTT SSSPPPTTIQ 60 FPVNLTCSHP RLPDHHTVIG EMDFFADKDT TLARDSNHSP TDTNHSISHN TDLDFNVNTG 120 LNLLTTNTSS DQSTVEDGTS TNMEDKRAKN ELAVLQAELE RMNAENQRLR DMLNQVTTNY 180 SSLQGHLVTL MQQQQQQQQQ QEDQKVEHND EHDQTIDGKG EEKRQNAAGL IVPRQFMDLG 240 LAAATDTDEL SLSSSDGSGS PVNHSEVGSK ELVIRKSTGN GEEGNIVLDQ DKKEFGRGIG 300 REDSPDQGRQ SWGGANKVPR FNSSKSVDQT EATMRKARVS VRARSEAPMI SDGCQWRKYG 360 QKMAKGNPCP RAYYRCTMAA GCPVRKQVQR CAEDRTILIT TYEGNHNHPL PPAAMAMAST 420 TSSAARMLLS GAMSSADGIM NSNFLARTLL PCSSSMATIS ASAPFPTVTL DLTQTPSTNP 480 LQFQRPPTQF PVPFPNPSQN LSNSPAAALL PQIFSQALYN QSKFSGLQMS QDIDHNSQLD 540 HHKSQSTAAQ QGIQQQPNSL ADTVTAATAA ITADPNFTAA LAAAITSIIG GSAAQPSSIS 600 GNNTSLAASS HSNGNINS*

Sequence ? help Back to Top

Protein Sequence Length: 619 aa Download sequence Send to blast

MAKGSGLSFD SDPSRFFLLK PTVLNSFPED NHDWKLINSH MDMDATPTTT SSSPPPTTIQ  60
FPVNLTCSHP RLPDHHTVIG EMDFFADKDT TLARDSNHSP TDTNHSISHN TDLDFNVNTG  120
LNLLTTNTSS DQSTVEDGTS TNMEDKRAKN ELAVLQAELE RMNAENQRLR DMLNQVTTNY  180
SSLQGHLVTL MQQQQQQQQQ QEDQKVEHND EHDQTIDGKG EEKRQNAAGL IVPRQFMDLG  240
LAAATDTDEL SLSSSDGSGS PVNHSEVGSK ELVIRKSTGN GEEGNIVLDQ DKKEFGRGIG  300
REDSPDQGRQ SWGGANKVPR FNSSKSVDQT EATMRKARVS VRARSEAPMI SDGCQWRKYG  360
QKMAKGNPCP RAYYRCTMAA GCPVRKQVQR CAEDRTILIT TYEGNHNHPL PPAAMAMAST  420
TSSAARMLLS GAMSSADGIM NSNFLARTLL PCSSSMATIS ASAPFPTVTL DLTQTPSTNP  480
LQFQRPPTQF PVPFPNPSQN LSNSPAAALL PQIFSQALYN QSKFSGLQMS QDIDHNSQLD  540
HHKSQSTAAQ QGIQQQPNSL ADTVTAATAA ITADPNFTAA LAAAITSIIG GSAAQPSSIS  600
GNNTSLAASS HSNGNINS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	2e-22	337	413	1	76	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_87.103

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021893820.1	0.0	probable WRKY transcription factor 31
Swissprot	Q9C519	1e-142	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A061DTF6	0.0	A0A061DTF6_THECC; WRKY family transcription factor
STRING	evm.model.supercontig_87.103	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1057	28	107
Representative plant	OGRP14	17	875

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-114	WRKY family protein

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_87.103

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]